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Method for Repurposing FDA-approved Therapeutics & Composition for Treating Mesothelioma
The amount of time and money that goes into getting a drug from initial discovery to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/8/2025   |   Inventor(s): Chris Plaisier, Sierra Wilferd, Choung Hoang
Keywords(s): Cancer, Drug, Drug Discovery
Category(s): Pharmaceuticals, Cancer, Cancer Therapeutics, Artificial Intelligence/Machine Learning, Computing & Information Technology, Life Science (All LS Techs)
Modified Simmons Catheter
​ ​ Neurointerventions with improved success Invention Summary: The global neurovascular catheter market size was valued at USD 2.88 billion in 2020 and is expected to expand at a compound annual growth rate of 6.7% from 2021 to 2028. Neurointerventionalists, interventional radiologists, cardiologists, and vascular surgeons often can have...
Published: 1/8/2025   |   Inventor(s): Amit Singla
Keywords(s): Neurological disorder & neuropathic pain
Category(s): Technology Classifications > Diagnostics, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Medical Devices
Antibacterial Coagulating Gel Spray
Blood loss and infections are a major cause of concern and death for traumatic injuries and wounds. It is estimated that blood loss accounts for more than 35% of all prehospital deaths in trauma patients. Thus, it is imperative that bleeding is stopped quickly and at the point of care. While there are many products to staunch bleeding, including gauze...
Published: 1/8/2025   |   Inventor(s): Emily Byrne, Grace Billingsley, Tran Nguyen, Alfonso Gomez-De Leon, Oscar Voeller, Sarah Stabenfeldt, Jessica Weaver
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Biomaterials, Life Science (All LS Techs), Medical Devices
Selective Modulators of Ah-R to Treat Cancer
Synergistic compositions and method of using modulators of Ah-R activity and synergistic compounds to treat cancer Background Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor. When activated by the binding of a wide range of both endogenous and exogenous small molecules, AhR signaling influences cellular outcomes in different...
Published: 1/8/2025   |   Inventor(s): Siva Kolluri, Bach Nguyen, Daniel Elson
Keywords(s):  
Category(s): Therapeutics
Pharmaceutical manufacturing of the future: a continuous 3D printing approach for personalized medicine
Background Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharma­ceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 1/8/2025   |   Inventor(s): Mohammed Maniruzzaman, Vineet Kulkarni, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Laser apparatus for micro-volume tissue excision
This technology uses a laser to remove tiny pieces of tissue for analysis. The laser is shaped into a ring and can be combined with cooling techniques to minimize damage. Background The traditional histopathology workflow, while considered the gold standard for tissue diagnosis, suffers from several limitations. These include the invasiveness of biopsies,...
Published: 1/8/2025   |   Inventor(s): Thomas Milner, James Tunnell, Jason King, Nitesh Katta
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Medical technology
Highly sensitive pressure sensor for diverse applications
A flexible, highly sensitive pressure sensor combines resistive and capacitive elements using a porous carbon nanotube–Eco flex material. It accurately detects a wide range of pressures, is easy to fabricate, and suits diverse applications like medical monitoring and environmental sensing. Background Pressure sensing technology plays a crucial...
Published: 1/8/2025   |   Inventor(s): Nanshu Lu, Kyoung-Ho Ha
Keywords(s):  
Category(s): Life sciences > Medical technology
Autonomous Brain Machine Interface
An advanced system that enables patients to better control prosthetic devices. Background: Many pathologies lead to loss of the ability to use one or more limbs. Historically, the lost or damaged limb is replaced with a prosthetic device. In recent years prosthetic technology has been developed to enable the control of these devices via a neural signal...
Published: 1/7/2025   |   Inventor(s): Joseph Francis, Venkata S. Aditya Tarigoppula, Brandi Marsh
Keywords(s):  
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Computers
Intramedullary Temporomandibular Joint (TMJ) Implant
A novel TMJ implant that reduces stress and strain on the patient. Background: The temporomandibular joint (TMJ) is involved in functions such as chewing, swallowing, and speaking. Degenerative disorders of the TMJ are typically treated with anti-inflammatory drugs. However, once the TMJ has been compromised, surgical treatment is commonly performed....
Published: 1/7/2025   |   Inventor(s): Martin Pendola
Keywords(s):  
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Medical Devices
Cancer treatment through hTERT inhibition
Title: Cancer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025   |   Inventor(s): Laurence Hurley, Vijay Gokhale, HyunJin Kang, Kui Wu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology
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