Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - s
16990
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Method
s
To Generate Constrained Fluorinated Macrocycles (UCLA Case No. 2023-139)
UCLA re
s
earchers from the Department of Chemistry and Biochemistry have developed a novel method to generate fluorinated polycycles, which may be used for downstream drug discovery and development. BACKGROUND: A significant amount of research in the field of organic chemistry centers around generating increasingly complex molecules that cyclize, forming...
Published: 5/30/2025
|
Inventor(s):
Patrick Harran
Keywords(s):
Drug Di
s
covery
Category(s):
Chemical >
S
ynthesis
,
Chemical > Cataly
s
ts
Modified Hyaluronic Acid Hydrogel
s
Containing Hyaluronidase for the Time‐Controlled and Targeted Release of anti-CTLA-4 and other Therapeutic Antibodies (UCLA Case No. 2016-526)
UCLA re
s
earchers from the Department of Medicine have developed a novel therapeutic platform for the administration of low-dose Cytotoxic T-lymphocyte Associated Protein 4 (CTLA-4) antibody for cancer immunotherapy that synergizes with conventional PD-1 therapy while sparing systemic autoimmune toxicity. BACKGROUND: Immune checkpoint inhibitor (CPI)...
Published: 5/30/2025
|
Inventor(s):
Michael Roth
,
Airi Harui
Keywords(s):
Cancer Immunotherapy
,
Immunotherapy
Category(s):
Platform
s
> Drug Delivery
,
Therapeutic
s
> Immunology And Immunotherapy
,
Therapeutic
s
> Oncology
A de
s
ign to manufacture polyamide reverse osmosis membrane using molecular layer-by-layer deposition
Thin-film compo
s
ite polyamide membranes, are the basis for modern commercial reverse osmosis (RO) membranes. These membranes are created through interfacial polymerization (IP) involving a trifunctional acid chloride (e.g., trimesoyl chloride, TMC, dissolved in an organic solvent) and a difunctional amine (e.g., m-phenylenediamine, MPD, dissolved in...
Published: 5/30/2025
|
Inventor(s):
S
amarpan Deb Majumder
,
Xitong Liu
Keywords(s):
Category(s):
Technology Cla
s
sifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
,
Technology Cla
s
sifications > Industrial or Consumer Tech > Industrial Manufacturing
Robot-Aided
S
ystem And Method For Diagnosis Of Autism Spectrum Disorder
S
ensory abnormalities are reported to be central to autistic experience. The symptoms include hyposensitivity, hypersensitivity, multichannel receptivity, processing difficulties and sensory overload. Given the intensive and cumbersome nature of current methods of diagnosis, there is a need of behavior-based approach to identify the children at risk...
Published: 5/30/2025
|
Inventor(s):
Chung Hyuk Park
,
Hifza Javed
Keywords(s):
Category(s):
Technology Cla
s
sifications > Diagnostics
,
Technology Cla
s
sifications > Medical Devices > Therapeutic Devices
Tampa Neuromapping Depth Electrode
Advantage
s
Combines recording and stimulation in a single device Reduces brain penetration and surgery time Lowers risk of hemorrhage, infection, and brain shift Enables precise brain mapping and real-time stimulation Summary Deep Brain Stimulation (DBS) helps patients with movement disorders like Parkinson’s disease by sending electrical...
Published: 5/30/2025
|
Inventor(s):
Oliver Flouty
,
Yarema Bezchlibnyk
,
Vi
s
hal Bharmauria
,
Nour
S
haheen
,
Brian Dalm
,
Can
S
arica
,
Matthew Howard
,
Hiroto Kawa
s
aki
,
Mario Zanaty
,
Alex Green
,
Andre
s
Lozano
Keywords(s):
Category(s):
Technology Cla
s
sifications > Medical > Neuroscience
Engineering A
s
ymmetrically Glycosylated IgG Antibodies
Application A novel method to develop a
s
ymmetrically glycosylated therapeutic monoclonal IgG antibodies for preventing and treating diseases like cancer, infectious diseases, and autoimmune disorders. Key Benefits Different IgG antibody glycoforms can be produced, each with its unique effector functions and biological and therapeutic effects. Potential...
Published: 5/30/2025
|
Inventor(s):
Eric J.
S
undberg
,
Jonathan Du
,
Tala Azzam
Keywords(s):
Antibodie
s
,
Immunology and Inflammation Treatment
s
,
Microbiology and Infectiou
s
Disease Treatments
,
Oncology Treatment
s
Category(s):
TechPub Algolia > Therapeutic
s
Companion Diagno
s
tic for Immunomodulatory Repair Treatments
Thi
s
technology is a diagnostic tool designed to help match patients to specific drugs or therapies to treat chronic ischemic heart failure. The platform focuses on immune cells called macrophages, which play a crucial role in the body's response to injury and disease. By promoting a specific type of macrophage known to aid healing, this system...
Published: 5/30/2025
|
Inventor(s):
S
teven Goldman
,
Daniel Ben
s
on
,
Adrian Grijalva
,
Jordan Fink
,
Jordan Lanca
s
ter
,
Jennifer Koevary
,
S
imar Singh
Keywords(s):
Category(s):
Technology Cla
s
sifications > Life Sciences > Diagnostics
,
Technology Cla
s
sifications > Research Tools > Screening assays
,
Technology Cla
s
sifications > Healthcare Portfolios > Heart and Vascular
RNA Binding Motif 3 (RBM3) Overexpre
s
sing Transgenic Mouse
Advantage
s
• RBM3 upregulation reverses multiple tau phosphorylations post-TBI • Novel RBM3 Overexpressing Transgenic Mouse Model allows researchers to study the effects of RBM3 activation on tissue function, brain function, and brain injury Summary Traumatic brain injury (TBI) not only causes immediate neuronal damage but also...
Published: 5/30/2025
|
Inventor(s):
Travi
s
Jackson
Keywords(s):
Animal Model
s
,
Neuro
s
cience
Category(s):
Technology Cla
s
sifications > Research Tools/Copyright > Animal Models
,
Technology Cla
s
sifications > Medical > Neuroscience
,
Technology Cla
s
sifications > Medical > Biotechnology
Method for Co-Localizing Two Protein
s
on the Inside of the Cell Membrane in Yeast
Advantage
s
Localization of protein interactions at the cell membrane offers a more physiologically relevant model Improved screening by minimizing off-target interactions Broadly applicable and accessible tools Summary Protein-protein interactions involving membrane proteins are notoriously difficult to study under physiologically relevant conditions....
Published: 5/30/2025
|
Inventor(s):
Lawrence
S
tern
,
Michael Nel
s
on
Keywords(s):
Drug Di
s
covery
Category(s):
Technology Cla
s
sifications > Medical > Cell & Tissue Engineering
,
Technology Cla
s
sifications > Medical > Medical Diagnostics
,
Technology Cla
s
sifications > Medical > Biomaterials
Tran
s
genic Foxc2-tdTomato Overexpressing Mouse Model for Study and Screening of Lymphatic Valve Development
Advantage
s
Tissue specific Foxc2 expression with integrated tdTomato fluorescent reporter enables precise spatiotemporal visualization Enables monitoring of lymphatic valve development 1:1 co-expression of Foxc2 and tdTomato, overcoming expression variability characteristic associated with of IRES-based or viral delivery systems Single-vector...
Published: 5/30/2025
|
Inventor(s):
Jo
s
hua Scallan
Keywords(s):
Animal Model
s
Category(s):
Technology Cla
s
sifications > Research Tools/Copyright > Animal Models
1
2
3
4
5
6
7
8
9
10
...