Search Results - point-of-need

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At-home diagnostic system for managing heart failure
Background In the past year, we have seen widespread adoption of at-home and drive-through diagnosis. Dispersion of the first line of healthcare is creating a massive opportunity to lower healthcare costs and improve disease management for millions of patients. With more than 5 million patients in the United States and 11 million physician visits each...
Published: 11/1/2023   |   Inventor(s): Richard Crooks, Ian Richards, Josephine Cunningham, Molly Kogan, Yi-Ju Tsai, Long Luo
Keywords(s): Diagnostics, Point-of-care, Point-of-need
Category(s): Life sciences > Diagnostic, Life sciences > Research tools > Tool/assay/screening platform
Bacterial reagents: stable, low-cost, readily available reagents with no purification requirements
Problem Most molecular biology techniques commonly used in research, biotechnology, healthcare, and education rely heavily on purified functional protein reagents. However, purification of these protein reagents requires substantial investment of time, expertise, equipment, and infrastructure. As a result, this significantly limits the availability...
Published: 11/1/2023   |   Inventor(s): Andrew Ellington, Sanchita Bhadra, Arti Pothukuchy, Michelle Byrom, Raghav Shroff, Jared Ellefson, Jimmy Gollihar
Keywords(s): Diagnostics, Isothermal amplification, Nucleic acid amplification, Point-of-need
Category(s): Life sciences > Research tools > Reagent, Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Therapeutics > Synthetic biology
Br512: an improved DNA polymerase for isothermal amplification assays
Unmet need Loop-mediated isothermal amplification (LAMP) is a technique that allows for nucleic acid amplification without the need for a thermocycler. This technology enables testing for infections practically anywhere. Testing shortages have exacerbated the COVID-19 pandemic, and there is a high demand for tests that can provide rapid results outside...
Published: 11/1/2023   |   Inventor(s): Andrew Ellington, Andre Maranhao, Sanchita Bhadra
Keywords(s): COVID-19, Diagnostics, Engineered enzyme, Isothermal amplification, LAMP, Nucleic acid amplification, Point-of-care, Point-of-need, Polymerase
Category(s): Life sciences > Research tools > Reagent