Search Results - nucleic+acid+amplification

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Bacterial reagents: stable, low-cost, readily available reagents with no purification requirements
Problem Most molecular biology techniques commonly used in research, biotechnology, healthcare, and education rely heavily on purified functional protein reagents. However, purification of these protein reagents requires substantial investment of time, expertise, equipment, and infrastructure. As a result, this significantly limits the availability...
Published: 11/1/2023   |   Inventor(s): Andrew Ellington, Sanchita Bhadra, Arti Pothukuchy, Michelle Byrom, Raghav Shroff, Jared Ellefson, Jimmy Gollihar
Keywords(s): Diagnostics, Isothermal amplification, Nucleic acid amplification, Point-of-need
Category(s): Life sciences > Research tools > Reagent, Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Therapeutics > Synthetic biology
Br512: an improved DNA polymerase for isothermal amplification assays
Unmet need Loop-mediated isothermal amplification (LAMP) is a technique that allows for nucleic acid amplification without the need for a thermocycler. This technology enables testing for infections practically anywhere. Testing shortages have exacerbated the COVID-19 pandemic, and there is a high demand for tests that can provide rapid results outside...
Published: 11/1/2023   |   Inventor(s): Andrew Ellington, Andre Maranhao, Sanchita Bhadra
Keywords(s): COVID-19, Diagnostics, Engineered enzyme, Isothermal amplification, LAMP, Nucleic acid amplification, Point-of-care, Point-of-need, Polymerase
Category(s): Life sciences > Research tools > Reagent
Device to Detect Viruses and Bacteria in Aerosols and Bodily Fluids for Point-of-Care Use
Primes Nucleic Acids for In-field Pathogen Analysis Without Lab EquipmentThis device enables preparation of collected RNA and DNA samples for enrichment, amplification, and analysis, allowing point-of-care detection of infectious microorganisms. International travel and dense city populations increase the ability of infectious diseases, such as Zika...
Published: 6/27/2021   |   Inventor(s): Chang-Yu Wu, Hugh Fan, John Lednicky, Xiao Jiang, Trevor Tilly
Keywords(s): Nucleic Acid Amplification, point of care, Sample preparation, Valve Actuation
Category(s): Technology Classifications > Engineering > Instrumentation-Sensors-Photonics, Technology Classifications > Environmental > Air, Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Others > Security