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Novel Immunotherapy for Cancer Treatment: Chimeric Antigen Receptors Targeting CD70 Antigen
Abstract: Scientists at the NCI's Surgery Branch have developed anti-CD70 chimeric antigen receptors (CARs) to treat cancers. CD70 is an antigen that is expressed on a variety of human cancers such as renal cell carcinoma, glioblastoma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia. The anti-CD70 CARs are hybrid proteins consisting of a receptor...
Published: 4/8/2024   |   Inventor(s): Qiong Wang, Zhiya Yu, James Yang
Keywords(s): CARS, CD70, chimeric antigen receptor, T-cell reprogramming
Category(s): TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing