Search Results - qianying+he

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DNAzyme-seq: a single-cell metal ion and transcriptome profiling platform
Background Metal ions such as zinc, copper, and calcium play indispensable roles in nearly every facet of cellular physiology, from enzymatic catalysis to signal trans­duction. However, conventional single-cell transcriptomics has largely over­looked the contribution of metal cofactors to gene expression, metabolism, and disease progression....
Published: 12/4/2025   |   Inventor(s): Yi Lu, Mandira Banik, Valeria Garcia, Ishika Rashed
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology > Genomics/genetics
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 12/5/2025   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
Design of Task-Specific Optical Systems Using Broadband Diffractive Neural Networks (Case No. 2020-174)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a diffractive neural network that can process an all-optical, 3D printed neural network for deep learning applications. Background: Deep learning, a method of machine learning that mimics the human brain’s connectivity through a series of “neural...
Published: 10/17/2025   |   Inventor(s): Aydogan Ozcan, Yi Luo, Deniz Mengu, Yair Rivenson
Keywords(s):  
Category(s): Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Image Processing
Task-Oriented Edge Metaverse for Smart Cities and Critical Systems
This invention introduces a task-oriented “Microverse” architecture that creates temporary, edge-based digital twins for 5G/IoT network slices. By combining real-time data fusion, per-task blockchain security, and immersive VR/AR interfaces, it delivers sub-second situational awareness and secure collaboration for smart cities, infrastructure,...
Published: 11/12/2025   |   Inventor(s): Yu Chen, Qian Qu
Keywords(s): Technologies
Category(s): Campus > Binghamton University
Cascadable All-Optical Nand Gates Using Diffractive Networks (Case No. 2022-107)
Summary UCLA researchers have developed cascadable, all-optical NAND gates built from passive diffractive neural networks, enabling logic operations (e.g. NAND, AND, OR, half-adder) via light propagation and diffraction rather than electronics, potentially lowering latency and power consumption. Background Traditional optical logic gates often rely...
Published: 9/11/2025   |   Inventor(s): Aydogan Ozcan, Yi Luo
Keywords(s):  
Category(s): Electrical, Electrical > Signal Processing, Electrical > Electronics & Semiconductors
Switchable Magnetic Device Holder
The Problem: The prolific use of mobile devices has driven demand for secure, convenient mounting solutions across various environments. Traditional docking stations often rely on adhesive pads and mechanical clamps can be bulky, not universally compatible, and difficult to operate with one hand. Suction based holders are prone to stability issues....
Published: 8/4/2025   |   Inventor(s): Greg Berkeley, Ian Shen
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Lifestyle & Leisure
Biocompatible photoenzymatic system for selective C–H fluorination
Background C–H fluorination plays a central role in pharmaceutical and agrochemical synthesis, as the introduction of fluorine often enhances a molecule's metabolic stability, potency, and bioavailability. Over 20% of approved drugs contain fluorinated functional groups, underscoring the demand for efficient and selective fluorination methods....
Published: 11/25/2025   |   Inventor(s): Yi Lu, Yu Zhou
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
Multi-List Strategy for Spectrum Interference Management
THE CHALLENGE Spectrum managers operating in shared-spectrum environments (e.g., the CBRS band) face a critical challenge: protecting high-priority incumbents such as Navy radar while maintaining reliable service for commercial users. Static move lists—the prevailing industry approach—repeatedly shut down the same base stations during...
Published: 11/17/2025   |   Inventor(s): Naru Jai, Yubo Wu, Yi Shi, Yiwei Thomas Hou
Keywords(s):  
Category(s): Technology Classifications > Communication
DNA-based sensors for live-cell mapping of metabolite- and metal ion-protein interactions
Background Understanding how metabolites and metal ions interact with proteins inside living cells is essential for decoding cellular signaling, metabolic regulation, and disease mechanisms. These small molecules function as cofactors, second messengers, and allosteric regulators, orchestrating critical pathways that govern cell behavior. However,...
Published: 11/25/2025   |   Inventor(s): Yi Lu, Mandira Banik
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Immunology > Genomics/genetics
Artificial nitrogenase enzymes for ambient-condition, decentralized ammonia production
Background Ammonia synthesis is foundational to global agriculture and chemical manufacturing, providing the primary source of fixed nitrogen for fertilizers, polymers, and pharmaceuticals. Traditional ammonia production through the Haber-Bosch process, however, operates under extreme conditions—temperatures exceeding 400°C and pressures...
Published: 11/25/2025   |   Inventor(s): Yi Lu, Hirbod Heidari, Markus Ribbe, Yilin Hu, Chi Chung Lee, Evan Mirts
Keywords(s):  
Category(s): Life sciences > Therapeutics > Synthetic biology, Life sciences > Metabolic engineering
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