Search Results - qianying+he

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Virus-like particles have been engineered for drug delivery, gene editing applications, mRNA delivery and overcoming barriers in mouse lungs. Background: Recent biomedical research has shown increased interest in the use of virus-like particles as a drug delivery vehicle. Current viral vectors have been shown to cause adverse immunological responses,...

Published: 5/28/2025 | Inventor(s): Sriram Neelamegham, Qi Yang

Keywords(s): Featured, Technologies

Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Drug Delivery, Technology Classifications > Healthcare, Technology Classifications > Gene Therapy, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays

Batch Processing for Imaris Stitcher (Case No. 2025-089)

Summary: Researchers in UCLA’s Department of Neurobiology have developed a novel software tool that enhances the capabilities of Imaris Stitcher. The tool enables batch processing and automated execution of multiple image stitching jobs, significantly improving workflow efficiency and reducing hands-on time. This results in readily available,...

Published: 5/13/2025 | Inventor(s): Ian Bowman, Mitchell Rudd, Hong Wei Dong

Keywords(s): 3D tissue imaging, 3D ultrasound imaging, Artifical Intelligence (Machine Learning, Data Mining), Artificial Intelligence, artificial intelligence algorithms, artificial intelligence augmentation, artificial intelligence/machine learning models, artificial-intelligent materials, bioimaging, Cell Counting/Imaging, cell imaging, cell mapping, computational imaging, Data Acquisition, Data Aggregator, Data Analytics, Data Recovery, Data Structure, Fluorescence Microscope, histopathology images, Image Analysis, image restoration, image signal processing, Imaging, Magnetic Resonance Imaging, Medical artificial intelligence (AI), Medical Imaging, Microscope, Microscopy, Microscopy And Imaging, Molecular Imaging, multi-contrast imaging, Neuroimaging, non-invasive imaging, pathology image analysis, Phase-Contrast Imaging, three dimensional imaging, volumetric image

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing

Functional Hierarchical Porous Organic Polymers for Water Purification

Advantages: High absorption capacity Fast and controllable kinetics Facile regeneration and recyclability Stable under a wide range of conditions High density of chelating sites Summary: Water and energy purification are important factors in minimizing the harsh impact of technology on the environment. Coal-powered fuel stations and waste...

Published: 3/4/2025 | Inventor(s): Shengqian Ma, Qi Sun, Briana Aguila

Keywords(s):

Category(s): Technology Classifications > Energy & Environment

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 5/30/2025 | Inventor(s): Yong Zeng, He Yan

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

Precision cellular imaging for advanced biological analysis

A novel DNA-based imaging technique enabling visualization of 3D cellular components with super-resolution. Background Super-resolution microscopy has revolutionized biological research by providing finer details beyond the diffraction limit of conventional microscopy. A particular challenge in this field is the visualization of small and dynamic...

Published: 3/4/2025 | Inventor(s): Yi Lu, Quanbing Mou

Keywords(s):

Category(s): Life sciences > Imaging, Life sciences > Research tools > Tool/assay/screening platform

DNAzyme sensor for selective manganese ion detection in biological systems

A selective DNAzyme-based fluorescent sensor detects manganese ions in cells by lighting up when Mn²⁺ binds, allowing precise monitoring of manganese levels for biological research and potential therapies. Background Manganese (Mn²⁺) is an essential trace element integral to numerous biological processes, acting as a vital cofactor for enzymes...

Published: 5/19/2025 | Inventor(s): Yi Lu, Zhenglin Yang, Huanhuan Fan

Keywords(s):

Category(s): Life sciences > Biomaterials

DNAzyme fluorescent sensors for bioselective imaging of Fe²⁺ and Fe³⁺ ions

Developed DNAzyme-based fluorescent sensors that specifically detect and image Fe2⁺ and Fe3⁺ ions in living cells, enabling the study of iron dynamics in biological processes and diseases like Alzheimer’s. Background Iron ions, specifically Fe2⁺ and Fe3⁺, are essential for numerous biological processes, including oxygen transport, DNA synthesis,...

Published: 5/19/2025 | Inventor(s): Yi Lu, Seyed-Fakhreddin Torabi, Yuting Wu, Ryan Lake, Zhenglin Yang, Whitney Lewis, Jacqueline Van Stappen, Xiangli Shao

Keywords(s):

Category(s): Life sciences > Biomaterials

DNA aptamer technology for Coenzyme A detection and cellular imaging

Researchers developed a DNA aptamer that specifically targets Coenzyme A, enabling easy and accurate detection in cells. This technology is more specific and simpler than current methods, supporting diagnostics, research, and treatments for diseases involving CoA imbalance. Background The field of biochemical research and medical diagnostics increasingly...

Published: 5/30/2025 | Inventor(s): Yi Lu, Whitney Besetzny, Yuan Ma

Keywords(s):

Category(s): Life sciences > Therapeutics > Drug screening, Life sciences > Research tools > Tool/assay/screening platform

Fluorogenic bioconjugation of cyclopropanol-containing fluorophores for biological applications

Reference #: 1742 The University of South Carolina is offering licensing opportunities for Fluorogenic bioconjugation of cyclopropanol-containing fluorophores for biological applications. Background: Fluorophores have been used in various applications of cellular microbiology, most notably with the reporting functions associated with various biological...

Published: 1/13/2025 | Inventor(s): Qian Wang, Shan Hu

Keywords(s):

Category(s): Chemistry and Biochemistry

HIGH OUTPUT, FLEXIBLE PIEZOELECTRIC DEVICES

Princeton Docket # 10-2585 Researchers at Princeton have developed a new design for highly flexible, high output piezoelectric assemblies. Princeton is seeking an industrial partner to commercialize this technology. Current and past devices have relied on low output piezoelectric compounds and mechanical...

Published: 4/10/2025 | Inventor(s): Michael McAlpine, Yi Qi

Keywords(s):

Category(s): Mechanical/Electrical Engineering

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