Search Results - ludmila+szabova

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Metastatic ovarian cancer mouse models and cell lines for preclinical studies
Abstract: The high mortality rate from ovarian cancers can be attributed to late-stage diagnosis and lack of effective treatment. Despite enormous effort to develop better targeted therapies, platinum-based chemotherapy still remains the standard of care for ovarian cancer patients, and resistance occurs at a high rate. One of the rate limiting factors...
Published: 4/8/2024   |   Inventor(s): Simone Difilippantonio, Terry Van Dyke, Ludmila Szabova, Chaoying Yin, Yurong Song
Keywords(s): GDA, GEM Derived Allograft Mouse Model, Genetically Engineered Mouse (GEM) Model, OVARIAN CANCER, SEOC, Serous Epithelial Ovarian Cancer
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials
Murine metastatic pancreatic adenocarcinoma cell lines
Abstract: Researchers at the National Cancer Institute (NCI) have developed orthotopic allograft models for pancreatic cancer that utilize low passage primary pancreatic adenocarcinoma cells or tumor fragments implanted into the cancer-free pancreata of recipient syngeneic immunocompetent mice. Tumor development in these models is more synchronized,...
Published: 4/8/2024   |   Inventor(s): Serguei Kozlov, Ludmila Szabova, Melanie Gordon, Myhaymin Kamal, Jerome Schlomer, Theresa Guerin, Theresa O'Sullivan, Terry Van Dyke
Keywords(s): ADENOCARCINOMA, CANCER, GEM-Derived Allograft, Inflammation, Kozlov, Mouse Models, Pancreatic
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
­Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023   |   Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA
Keywords(s): Drug Discovery, Immunology
Category(s): Technology Classifications > Medical > Biotechnology
Medical Imaging Software that Improves Image Quality Without Exposing Patient to Longer X-Rays
Algorithm Enables Precise Verification of Mobile Internal Organs and Tumors Using Image ReconstructionThis software reconstructs high quality Four-Dimensional Cone-Beam Computer Tomography (4D-CBCT) images using limited imaging projections and a standard free breathing CBCT scan. Roughly two–thirds of all cancer patients receive radiotherapy to...
Published: 6/27/2021   |   Inventor(s): Yunmei Chen, Bo Lu, Chunjoo Park, Hao Zhang
Keywords(s): 4DCBCT, compressed sensing, iterative image reconstruction, cmpressed sen, online-IGRT
Category(s): Technology Classifications > Engineering > Computer Science, Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Medical Devices > Others
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology