Search Results - medical+diagnostics%2fsensors

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Reagent Molding Process for Point of Care Microfluidic Applications
Invention Description Lyophilization is a critical process for stabilizing reagents in point-of-care (POC) diagnostics, effectively eliminating the need for cold chain storage and preventing liquid evaporation. While this technology is essential for developing robust field-deployable devices, current industry standards are limited to producing reagents...
Published: 1/26/2026   |   Inventor(s): Jennifer Blain Christen, Vi Nguyen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care
Integrated Microfluid Cartridge for POC Biofluid Diagnostics
Invention Description Rapid and reliable nucleic acid assays are critical for diagnosing infectious diseases at the point of need, yet most systems rely on complex, expensive instrumentation and trained personnel. These requirements limit access to timely diagnostics in low-resource, remote, or decentralized settings. Many platforms typically require...
Published: 1/6/2026   |   Inventor(s): Vi Nguyen, Clifford Anderson, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Coronavirus, COVID-19, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Point of Care, SARS-CoV-2
Ultra-Sensitive Wireless Capacitive Nanocomposite-Based Pressure Sensors
Invention Description Wireless capacitive pressure sensors have been widely studied for health monitoring applications including continues monitoring of blood flow in patients suffering from high blood pressure, tracking of bladder pressure in patients with urine incontinence, and monitoring intracranial pressure in patients experiencing traumatic...
Published: 12/12/2025   |   Inventor(s): Layla Khalifehzadeh, Hamed Arami, Seyedamin Hashemi, Saman Ebrahimibasabi, Mostafa Sajjadi
Keywords(s):  
Category(s): Wearable, Medical Diagnostics/Sensors, Medical Devices, Physical Science, Advanced Materials/Nanotechnology
Unified Model of Alzheimer’s Disease Pathobiology
Invention Description Understanding of the pathobiology of Alzheimer’s disease (AD) has long been fragmented, with much research centered around biological mechanisms including amyloid β or tau proteins, inflammation, cell death pathways, glia, mitochondria and more. While these all deal with real facets in the biology of AD, they are limited...
Published: 1/6/2026   |   Inventor(s): Carol Huseby, Elaine Delvaux, Paul Coleman
Keywords(s):  
Category(s): Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors, Neurodegenerative Disease Technologies, Pharmaceuticals
Microfluidic Device Design for Point-of-Care Devices
Implementing liquid-based assays, such as PCR and LAMP, is difficult in POC microfluidic devices, due to bubble formation. To mitigate this, auxiliary metering systems or actuators are required to regulate consistent flow rates. This can make the microfluidic device more complicated to operate, increases cost, and limits rapid prototyping, ultimately...
Published: 9/29/2025   |   Inventor(s): Vi Nguyen, Jennifer Blain Christen
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Manufacturing/Construction/Mechanical, Medical Diagnostics/Sensors, Genomic Assays/Reagents/Tools
POC-Pure: Rapid, Cost-Effective Nucleic Acid Extraction for Point-of-Care Salivary Diagnostics on a Microfluidic Chip
Point-of-care (POC) testing techniques are essential in molecular diagnostics, particularly in resource-limited settings. The first step in molecular diagnostics is sample preparation which may include extraction of nucleic acids (NAs). Simple and efficient NA extraction is crucial for downstream applications such as pathogen detection, genetic analysis,...
Published: 9/18/2025   |   Inventor(s): Siril Arockiam, Karen Anderson
Keywords(s):  
Category(s): Life Science (All LS Techs), Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Medical Diagnostics/Sensors
Antibody based reagents that specifically recognize toxic oligomeric forms of beta-amyloid
Neurodegenerative diseases such as Alzheimer’s are affecting an increasing number, with annual new diagnoses approaching one-half million; and total cost, $150 billion. Early diagnosis and treatment are important for optimal outcomes, yet there is currently no test to detect such diseases in their early, asymptomatic stages. Active immuniza-tion...
Published: 8/27/2025   |   Inventor(s): Michael Sierks, Srinath Kasturirangan
Keywords(s): Bio-Technology, Therapeutics
Category(s): Life Science (All LS Techs), Diagnostic Assays/Devices, Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors
Targets and Methods of Diagnosing, Monitoring & Treating Frontotemporal Dementia
Diverse pathologies, especially related to early protein misfolding and aggregation, are observed in different neurodegenerative diseases. Some protein variants result in different proteinopathies that vary from patient to patient, highlighting a need for personalized diagnostic tests to enable accurate diagnoses. Frontotemporal dementia (FTD) refers...
Published: 8/27/2025   |   Inventor(s): Stephanie Williams, Michael Sierks
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Medical Diagnostics/Sensors, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Neurodegenerative Disease Technologies
Massively Parallel Method to Quantify Protein Folding & Stability
Protein misfolding plays a role in degenerative diseases, cancer evolution, synthetic biology, bioproducts, and more. Despite its importance in all of these fields, researchers often struggle to understand even the basic mechanisms of protein misfolding. For example, there is no tool to determine how much misfolding is happening inside of any given...
Published: 8/19/2025   |   Inventor(s): Yuichi Eguchi, Kerry Geiler-Samerotte
Keywords(s):  
Category(s): Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Medical Diagnostics/Sensors
Rapid Culture-Free Large-Volume Scattering Imaging for UTI Pathogen Detection and Antibiotic Susceptibility Testing
Antibiotic resistance is a significant public health threat, in part due to the misuse and overuse of broad-spectrum antibiotics. Most antimicrobial susceptibility testing (AST) techniques are slow and culture-based, taking days to produce results, which delays treatment and can put patients at risk. Dipstick-type tests and manual microscopy are faster,...
Published: 8/5/2025   |   Inventor(s): Shaopeng Wang, Brandyn Braswell, Jiapei Jiang
Keywords(s):  
Category(s): Diagnostic Assays/Devices, Artificial Intelligence/Machine Learning, Life Science (All LS Techs), Medical Diagnostics/Sensors, Medical Imaging
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