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First in class Small Molecule Agonists of the mammalian Relaxin family receptor 1 (RXFP1) and use in treatment of cancer, fibrotic, and vascular disorders (HHS Ref No. E-145-2024-0-US-02)
It is well documented in literature that activation of RXFP1 by relaxin induces: 1) up-regulation of the endothelin system which leads to vasodilation; 2) extracellular matrix remodeling through regulation of collagen deposition, cell invasiveness, proliferation, and overall tissue homeostasis; 3) a moderation of inflammation by reducing levels of inflammatory...
Published: 5/30/2025   |   Inventor(s): Juan Marugan, Mark Henderson, Kenneth Wilson, Wenwei Huang, Wenjuan Ye, Noel Southall, Jiankang Jiang, Khalida Shamim, Bing Li, Alexander Agoulnik, Abhijeet Kapoor, Joshua Hutcheson, Ana Cabrera, Irina Agoulnik
Keywords(s):  
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Pulmonology, TherapeuticArea > Dermatology, TherapeuticArea > Reproductive Health, TherapeuticArea > Geriatrics
Nanocage Sensors
The molecular nanocage concept can verify the purity and authenticity of agricultural products and could detect environmental contaminants Background: Increasing globalization and competition has created large economic incentives to commit food fraud by adding adulterants, fillers, or other inauthentic ingredients to agricultural products. Consequently,...
Published: 5/21/2025   |   Inventor(s): Jianing Li, Severin Schneebeli, Mona Sharafi
Keywords(s):  
Category(s): Technology Classifications > Agriculture, Technology Classifications > Biomedical
PAC1R Inhibitors for Treatment of Pain and Stress Related Disorders
PACAP signaling has been identified in multiple intersecting stress and pain associated pathologies Background: The healthcare and loss of productivity costs of pain and stress related disorders now exceed those of cardiovascular disease, cancer and diabetes. More than 65 million adults are affected by anxiety disorders in the United States and Europe...
Published: 5/21/2025   |   Inventor(s): Victor May, Matthias Brewer, Jianing Li
Keywords(s):  
Category(s): Technology Classifications > Biomedical
Enhancing Sequence Generation with Rollout Algorithms
Background Generative pre-trained transformers (GPT) have grown in recent years in a number of natural language processing applications, largely due to the powerful openly available software and easy-to-use natural language interfaces. Transformers can provide a flexible and powerful model that generalizes the earlier forms of neural networks by using...
Published: 5/20/2025   |   Inventor(s): Dimitri Bertsekas, Yuchao Li
Keywords(s):  
Category(s): Physical Science, Wireless & Networking, Artificial Intelligence/Machine Learning
Diagnosis of hypertrophic cardiomyopathy and left ventricular hypertrophy using frequency domain analysis of ECG signals
Background Cardiac conditions involving abnormal thickening of the heart muscle, such as hypertrophic cardiomyopathy (HCM) and left ventricular hypertrophy (LVH), present significant diagnostic challenges due to their overlapping symptoms and similar manifestations in standard ECG readings. Existing diagnostic methods—including echocardiograms,...
Published: 5/19/2025   |   Inventor(s): Dongmei Chen, Edward Kim, Wei Li
Keywords(s):  
Category(s): Computer > Algorithms and software methods > Healthcare, Computer > Algorithms and software methods
SonicSurf Manipulator
THE CHALLENGE Developing advanced contactless manipulation technologies lies in creating a solution that is not only technically effective but also scalable, affordable, and easy to integrate into real-world biomedical and chemical workflows. Current methods—like optical tweezers, magnetic actuators, and traditional acoustic systems—are...
Published: 5/13/2025   |   Inventor(s): Zhenhua Tian, Teng Li, Jiali Li, Luyu Bo
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Engineering
SonicSurf Manipulator
THE CHALLENGE Developing advanced contactless manipulation technologies lies in creating a solution that is not only technically effective but also scalable, affordable, and easy to integrate into real-world biomedical and chemical workflows. Current methods—like optical tweezers, magnetic actuators, and traditional acoustic systems—are...
Published: 5/13/2025   |   Inventor(s): Zhenhua Tian, Teng Li, Jiali Li, Luyu Bo
Keywords(s):  
Category(s): Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Engineering
Advanced Mobile Navigation and Mapping App
­Improves mobile mapping and navigation apps by visualizing distant landmarks that typically fall outside the device display area. Background: Existing mobile map or navigation apps generally provide directions through distance and turn-by-turn instructions – for example, “after 1 mile, turn right on to Lakeview street.” Directions...
Published: 5/13/2025   |   Inventor(s): Rui Li, Jiayan Zhao
Keywords(s): augmented reality, autonomous vehicle, spatial cognition, Technologies, visualization, wayfinding and navigation
Category(s): Campus > University at Albany, Technology Classifications > Electronics, Technology Classifications > Instrumentation, Technology Classifications > Wireless Technologies
Albany Rural Cemetery Explorer and Grave Finder (Apps)
Provides an online tool for exploring the Albany Rural Cemetery, allowing visitors to find graves, view themed tours virtually or on mobile phones in the cemetery with composed biographies of individual graves, and enjoy the cemetery’s natural beauty. Background: Albany Rural Cemetery (ARC), located in Menands, New York, is one of the oldest...
Published: 5/13/2025   |   Inventor(s): Rui Li, Kurt Swartz, Jackson LaSarso, James Billings
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Education and Training, Technology Classifications > Information Technology, Technology Classifications > Social Sciences
Modifying Angiogenic Sprouting Using Pulsed Electromagnetic Fields (PEMF)
­ A novel method for the treatment of chronic wounds based on amplitude-modulated pulsed electromagnetic fields (PEMFs). Background: Chronic wounds adversely impact the quality of life and health of patients and their families, due to pain, anxiety, loss of function, loss of mobility, depression, shame, and social isolation. Wound healing requires...
Published: 5/13/2025   |   Inventor(s): Linghong Li, Wayne Patton
Keywords(s): angiogenic sprouting, autophagy-lysosomal pathway, cytoplasmic granulation, electromagnetic field, ion cyclotron resonance, sprouting, Technologies
Category(s): Campus > SUNY Potsdam, Technology Classifications > Healthcare, Technology Classifications > Medical Devices
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