Search Results - luciano+di+croce

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Various antitumoral targets identified from an unbiased multiomics screen on H3K27M mutated Diffuse Midline Glioma patient-derived material. We are finalizing target validation and developing high throughput small molecule screening assays to develop novel compounds that can be used to treat this devastating childhood cancer. Technology: Diffuse...

Published: 10/28/2024 | Inventor(s): Luciano Di Croce, Maria Espejo Diaz

Keywords(s): Epigenetics, Oncology, Paediatric Disease

Category(s): Drug Targets & Mechanisms, Therapeutics (Biologics & Compounds)

y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability

Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...

Published: 9/25/2023 | Inventor(s): Jianfeng Cai, Shibo JIANG, Lu LU, Songyi XUE, Xinling WANG, Lei WANG, Wei XU, Shuai XIA

Keywords(s): Drug Discovery, Immunology

Category(s): Technology Classifications > Medical > Biotechnology

Nature-inspired Functionally-graded UHMWPE + Kevlar Composites Achieve Extraordinarily High Strength

Nature-inspired polymers are achieved using unique processing to yield functional gradient composites with embedded Kevlar fibers exhibiting extraordinarily high strength lightweight UHMWPE materials. Background: Demand for new energy absorption materials and implantable polymeric biomaterials has increased significantly in recent years. The...

Published: 10/17/2024 | Inventor(s): Shenqiang Ren, Lu An

Keywords(s): Technologies

Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Technology Classifications > Engineering

New use of vanoxerine dihydrochloride as an anti-cancer drug for the treatment of liver cancer

Published: 1/26/2022 | Inventor(s): Kwong Sak LEUNG, Xi Nan Shi, Fu Kung Hsiang, Hongjian Li, Man Hon Wong, Chia Mi Marie Lin, Xu Liu, Di Lu

Keywords(s): Anti-cancer Drug, Docking Screening, Fluspirilene, Hepatocellular Carcinoma

Category(s): Biotechnology, Therapeutics

Network-Coded Multiple Access

[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...

Published: 1/29/2024 | Inventor(s): Soung Chang Liew, Lu LU, Lizhao You

Keywords(s): Network Coding, Wireless Local Area Network

Category(s): Information and Communications Technology