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Search Results - ling+zhang
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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025
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Inventor(s):
Li Li
,
Shichao Wu
,
Jiawei Zhao
Keywords(s):
Category(s):
Technology Category > Research tools
,
Technology Category > Animal models
,
Technology Category > Biology
,
Technology Category > Diagnostic
Ultrafast Thin-Film Vapor Deposition Technique
Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...
Published: 11/18/2025
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Inventor(s):
Feng Yan
,
Lin Li
Keywords(s):
Category(s):
Semiconductors, Materials & Processes
,
Microelectronics
,
Physical Science
,
Semiconductor Devices
,
Manufacturing/Construction/Mechanical
Cancer Therapeutic Based on T Cell Receptors Designed to Regiospecifically Release Interleukin-12
Abstract: Adoptive immunotherapy is a promising new approach to cancer treatment that engineers an individual''s innate and adaptive immune system to fight against specific diseases, including cancer with fewer side-effects and more specific anti-tumor activity in individual patients. T cell receptors (TCRs) and Chimeric Antigen Receptors (CARs) are...
Published: 4/22/2025
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Inventor(s):
Richard Morgan
,
Nicholas Restifo
,
Steven Rosenberg
,
Ling Zhang
Keywords(s):
CARS
,
chimeric antigen receptor
,
human interleukin 12
,
IL-12
,
T Cell Receptor
,
TCRs
Category(s):
Collaboration Sought > Collaboration
,
Application > Therapeutics
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
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Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Medical Imaging
,
Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors
Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...
Published: 1/9/2026
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Inventor(s):
Michael Keidar
,
Li Lin
,
Vikas Soni
,
Xiaoliang Yao
,
Dayun Yan
,
Jonathan Sherman
Keywords(s):
Category(s):
Technology Classifications > Medical Devices
,
Technology Classifications > Medical Devices > Surgical
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Cold atmospheric plasma-stimulated media for treating cancers
For successful cancer therapy, the most important aspect is selective eradication of cancer cells without damaging healthy cells. Cancer cells and normal cells have different thresholds for tolerance of reactive oxygen species (ROS) and reactive nitrogen species (RNS) before cell death (apoptosis) is induced. Previously, GW researchers invented a cold...
Published: 1/9/2026
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Inventor(s):
Michael Keidar
,
Zhitong Chen
,
Xiaoqian Cheng
,
Li Lin
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Cells
,
Technology Classifications > Therapeutics
Methods for the Manufacture of Thermal Interfaces, and Articles Comprising The Same
INV-20009 Background Circuit designs for electronic devices such as televisions, radios, computers, medical instruments, business machines, and communications equipment have become increasingly smaller and thinner over time. The increasing power of such electronic components has resulted in increased heat generation during use. Moreover, smaller...
Published: 1/7/2026
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Inventor(s):
Randall Erb
,
Anvesh Gurijala
,
Li Zhang
,
Anvesh Gurijala
,
Qiaochu Han
Keywords(s):
Category(s):
Technology Classifications > 2. Physical Science > Electronics/Semiconductors
,
Not in use > -Materials
,
Not in use > -Magnetics
Multilayer Batch Microfabricated Magnetic Shielding
UCLA Case No. 2018-014 SUMMARYUCLA researchers in the Department of Electrical Engineering have developed a novel batch microfabrication technique for microscale shielding layers, simultaneously pushing the limits of minimum size, maximum shielding factor, flexibility, and cost.BACKGROUNDCompact electromagnetic shielding paves the way for a new generation...
Published: 7/17/2025
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Inventor(s):
Robert Candler
,
Jimmy Chen-Yen Wu
,
Ling Li
,
Jere Harrison
Keywords(s):
Electronics & Semiconductors
Category(s):
Electrical > Electronics & Semiconductors
,
Materials > Fabrication Technologies
Novel Coronatine-Based Herbicide Treatment Platform with Increased Pathogen Resistance for Crop Plants
Executive SummaryDespite best efforts and current technology to enhance agricultural productivity, it’s estimated that insect pests and disease reduce the value of several major world crops, including rice, wheat, and corn by 20-37% annually. Considering more and more pests are becoming resistant to common agrochemical treatments, a crop plant...
Published: 8/20/2022
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Inventor(s):
Sheng-Yang He
,
Li Zhang
,
Jian Yao
,
Rahul Banerjee
,
John Withers
Keywords(s):
Category(s):
Agriculture
,
Biotechnology
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