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Search Results - jian-ting+zhang
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PTH1R PROTAC
Project ID: TECH-2025-20 Background Every 16 mins a man will die of Prostate cancer. Bone metastasis is the predominant cause of morbidity and mortality in prostate cancer, with > 80 % of lethal cases exhibiting skeletal involvement. Parathyroid hormone-related protein (PTHrP), secreted by tumor cells, binds and activates PTH1R on osteoblasts and...
Published: 6/25/2025
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Inventor(s):
Xiaohong Li
,
Shang Su
,
Tim (Qingbin) Cui
,
Jian-Ting Zhang
Keywords(s):
Category(s):
Oncology
Survivin Inhibitors for Targeted Cancer Treatment
Project ID: TECH-2024-07 Background Prostate cancer is one of the most common cancers and the second-most lethal cancer among men in the United States. While the response to standard androgen deprivation therapy (ADT) is often dramatic, most prostate cancer patients develop resistance to ADT, leading to castration-resistant prostate cancer (CRPC)....
Published: 2/13/2025
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Inventor(s):
Jian-Ting Zhang
,
Jasmine (JingYuan) Liu
,
Tim (Qingbin) Cui
Keywords(s):
Category(s):
Oncology
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
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Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
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Technology Classifications > Imaging & Optics > Medical Imaging
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Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
Bi-Functional RGD Peptide and a Co-Signaling Mechanism to Promote Therapeutic Angiogenesis
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases Technology: While previous studies have focused on the identification of biological ligands to improve the functions of endothelial cells, MUSC and Clemson University researchers have combined modern bioinformatics and a newly established peptide functionalized...
Published: 3/23/2023
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Inventor(s):
Chung-Jen (James) Chou
,
Ying Mei
,
Jia Jia
Keywords(s):
Category(s):
BioPharma
Cold Sterilization of Tissue Engineering Scaffolds with Compressed Carbon Dioxide
Reference #: 00774The University of South Carolina is offering licensing opportunities for this technologyInvention Description:A process for sterilizing tissue engineering materials by using compressed carbon dioxide into which selected additives have been incorporated. This method is effective for sterilizing complex structures, without causing adverse...
Published: 6/4/2018
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Inventor(s):
Michael Matthews
,
Jian Zhang
,
Aidaris Jimenez
Keywords(s):
Category(s):
Biomedical and Life Sciences
Methods and Compositions for Inactivating Allergens and Allergen-Producing Organisms
Reference #: 00690The University of South Carolina is offering licensing opportunities for this technologyPotential Applications:This technology has the potential to be used on a full-scale industrial level for purposes such as home carpet cleaning.Advantages and Benefits:With the combination of killing and removing dust mites and dust mite feces, indoor...
Published: 2/2/2018
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Inventor(s):
Michael Matthews
,
Jian Zhang
Keywords(s):
Category(s):
Chemistry and Biochemistry