Search Results - jon+dobson

8 Results Sort By:
Support Medium for 3D Printing Silicone Structures with Fine Features
Ultra-Low Interfacial Tension Material Enables High-Precision Silicone 3D Printing This 3D printing support material allows for liquid ink-printed silicone structures to have features as small as 8 microns. Silicone is a highly useful material due to its high thermal stability and resistance to weathering, ozone, moisture, and UV radiation. However,...
Published: 8/21/2024   |   Inventor(s): Thomas Angelini, Senthilkumar Duraivel, Jon Dobson, Brent Sumerlin
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Engineering > Mechanical
3D Bio-Printed Functional Liver Tissue Model
Predicts Liver Toxicity during the Drug Development Process This 3D bio-printed liver tissue model, which exhibits the functions of a human liver, tests for and predicts the liver toxicity of new drug therapies. Current approaches used in testing the potential liver toxicity in a compound during the drug development process are animal models and in...
Published: 11/13/2023   |   Inventor(s): Thomas Angelini, Glyn Palmer, Jon Dobson, Peter McFetridge, Clayton Mathews, Brent Sumerlin, Steven Chisolm, Vignesh Subramaniam, Carolina Abrahan, Andreas Baudy, Brett Higgins
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Diagnostics
Perfusion Bioreactor for 3D Cell Culture and Cell Printing
Bioreactor Delivers Nutrients and Removes Cellular Waste Using Capillary Forces This bioreactor enables the 3D printing and maintenance of living cells via the perfusion of nutrients driven by capillary forces through a standard well plate. 3D cell culture technology has grown rapidly in the past several years with many advantages over 2D cell culture,...
Published: 9/7/2022   |   Inventor(s): Thomas Angelini, Jon Dobson, Malisa Sarntinoranont, Cameron Morley, Obiora Azie, Peter McFetridge
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Research Tools > Diagnostics
Diagnostic Tool for Early Detection of Brain Disease Risks and Cancer
Detects Small Amounts of Iron in the Brain Facilitating Early Detection and Treatment of Neurodegenerative DiseasesThis diagnostic software/hardware tool detects unusual iron deposits in the living human brain and other tissue. These deposits may indicate risk for neurodegenerative diseases, such as Alzheimer's or Parkinson's, before symptoms occur....
Published: 6/27/2021   |   Inventor(s): Keith White, Yunmei Chen, Mark Davidson, Jon Dobson
Keywords(s): Early Detection of Alheimers, Neuro Degenerative Dissease Diagnosis
Category(s): Technology Classifications > Research Tools > Diagnostics
Magnetic Particle Conjugates for Remote Control of Tissue Formation
Controls Cell Activation Processes for Stem Cell Differentiation, Apoptosis or Tissue Matrix ProductionThese targeting agents use nucleic acid aptamers conjugated with magnetic nanoparticles to target cell surface receptors that make it possible to remotely control cell signaling for stem cell differentiation, apoptosis or tissue matrix production....
Published: 6/27/2021   |   Inventor(s): Jon Dobson, Josephine Allen, Adam Monsalve
Keywords(s): Aptamer, Cell Activation, magnetic materials, Nanotechnology, Tissue Engineering
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Others
Magnetic Remote Targeting System for Controlling the Activity of Growth Factors
Provides Control of the Distribution and Activity of Growth Factors Used in Tissue Regeneration These magnetic nanoparticles conjugated with transforming growth factor beta (TGF-ß) and its latent complex accurately target delivery to specific locations and remotely activate or deactivate the growth factor, greatly augmenting the potential of TGF-ß...
Published: 6/27/2021   |   Inventor(s): Jon Dobson, Adam Monsalve
Keywords(s): Biomedical Engineering, Growth factors, magnetic, Nanoparticles, regenerative medicine, Tissue Engineering
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Magnetically-triggered Drug Delivery System for Growth Factors and Biomacromolecules
Allows Externally-Controlled Delivery of Large Macromolecules for Dynamic, Spatial and Temporal Release Of BiologicsThis drug delivery system addresses the previously unmet need of a controlled drug-release platform for large biomolecules, such as growth factors and proteins. Controlled drug-release technology is one of the most rapidly growing technologies...
Published: 6/27/2021   |   Inventor(s): Jon Dobson, Peter McFetridge, Olivia Lanier
Keywords(s): biologic, Growth factor, Microparticle
Category(s): Technology Classifications > Human Health Care > Drug Delivery
Magnetic Nanoparticles and Microneedle Tip That Collect Biomarkers for Safe, Early-Stage Arthritis Diagnosis and Monitoring
Allows for Early Intervention, Which Can Delay Osteoarthritis ProgressionThese magnetic nanoparticles and specialized magnetic microneedle tips safely collect biomarkers that indicate early-stage osteoarthritis in knees, hips and other joints. Osteoarthritis affects 12.1 percent of American adults - nearly 27 million people, costing the nation an estimated...
Published: 6/27/2021   |   Inventor(s): David Arnold, Jon Dobson, Elena Yarmola, Zachary Kaufman, Kyle Allen
Keywords(s): inflammatory mediators, Interferon gamma, interleukin-1, interleukin-6, Magnetic Nanoparticle, prostaglandin E, tumor necrosis factor
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Medical Devices