Search Results - thomas+angelini

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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Ultrafast Thin-Film Vapor Deposition Technique
Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...
Published: 11/18/2025   |   Inventor(s): Feng Yan, Lin Li
Keywords(s):  
Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical
Support Medium for 3D Printing Silicone Structures with Fine Features
Ultra-Low Interfacial Tension Material Enables High-Precision Silicone 3D Printing This 3D printing support material allows for liquid ink-printed silicone structures to have features as small as 8 microns. Silicone is a highly useful material due to its high thermal stability and resistance to weathering, ozone, moisture, and UV radiation. However,...
Published: 1/20/2026   |   Inventor(s): Thomas Angelini, Senthilkumar Duraivel, Jon Dobson, Brent Sumerlin
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Engineering > Mechanical
3D-Printed Extracellular Vesicles (EVs) for DNA/RNA Sequencing
Enables Single Vesicle DNA/RNA Sequencing to Differentiate Sub-Populations of Extracellular Vesicles (EVs) These 3D-printed extracellular vesicle (EV) droplets enable DNA and RNA sequencing to differentiate extracellular vesicle subpopulations. Extracellular vesicles are nanosized vesicles containing a variety of cargo, including mRNA, proteins, and...
Published: 1/20/2026   |   Inventor(s): Thomas Schmittgen, Thomas Angelini, Andrew Brock, Jinmai Jiang, Senthilkumar Duraivel
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Others, Technology Classifications > Human Health Care, Technology Classifications > Human Health Care > Diagnostics
Coherent Generation Of High-Dimensional Structured Light Using A Hyperdimensional Spin-Orbit Microlaser
The current invention describes next-generation high-capacity noise-resilient communication and computing technology. The invention describes a method to coherently generate high-dimensional structured light, including spin-orbit states, in an integrated and scalable way. Problem: On-chip information technologies are mostly limited to two-level systems...
Published: 1/13/2026   |   Inventor(s): Liang Feng, Zhifeng Zhang, Haoqi Zhao, Li Ge
Keywords(s): Augmented Reality (AR) & Virtual Reality (VR), Microlasers, Optics & Photonics 
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Materials, Technology Classifications > Imaging
3D Bio-Printed Functional Liver Tissue Model
Predicts Liver Toxicity during the Drug Development Process This 3D bio-printed liver tissue model, which exhibits the functions of a human liver, tests for and predicts the liver toxicity of new drug therapies. Current approaches used in testing the potential liver toxicity in a compound during the drug development process are animal models and in...
Published: 1/20/2026   |   Inventor(s): Thomas Angelini, Glyn Palmer, Jon Dobson, Peter McFetridge, Clayton Mathews, Brent Sumerlin, Steven Chisolm, Vignesh Subramaniam, Carolina Abrahan, Andreas Baudy, Brett Higgins
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Diagnostics
Charge-Neutral Microgels for 3D Cell Culture and Printing
Improves permeability, allowing for easier perfusion than previous compositions These charge-neutral microgels allow for 3D cell culture and printing. Bioprinting, or placement of biological samples into 3D support media, models cellular morphology, heterogeneity, and genetic profiles in a more accurate and reproducible fashion than traditional 2D...
Published: 1/20/2026   |   Inventor(s): Thomas Angelini, Brent Sumerlin, Christopher O'Bryan, Georg Scheutz
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Diagnostics
Perfusion Bioreactor for 3D Cell Culture and Cell Printing
Bioreactor Delivers Nutrients and Removes Cellular Waste Using Capillary Forces This bioreactor enables the 3D printing and maintenance of living cells via the perfusion of nutrients driven by capillary forces through a standard well plate. 3D cell culture technology has grown rapidly in the past several years with many advantages over 2D cell culture,...
Published: 1/20/2026   |   Inventor(s): Thomas Angelini, Jon Dobson, Malisa Sarntinoranont, Cameron Morley, Obiora Azie, Peter McFetridge
Keywords(s):  
Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Research Tools > Diagnostics
Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors
Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...
Published: 1/9/2026   |   Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
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