Search Results - john+(andy)+berglund

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Use of Quercetin and Related Flavonoids for the Treatment of Myotonic Dystrophy Types 1 and 2
A novel flavonoids-based therapeutic strategy for the treatment of myotonic dystrophy and potentially repeat expansion disorders. Background: Myotonic dystrophy (DM) is the most common form of adult muscular dystrophy. It is a multisystemic disorder affecting nearly all organs including muscles, brain, heart, eyes, and the GI tract, among others....
Published: 10/24/2025   |   Inventor(s): John Berglund, Subodh Mishra, Kaalak Reddy, John Cleary
Keywords(s): drug discovery, drug efficacy, myotonic dystrophy, RNA, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
Autoregulated MBNL Gene Therapy for Myotonic Dystrophy
Next-Generation Gene Therapy Vectors with Tunable, Tissue-Specific, and Auto-Regulated Expression for Superior Safety and Efficacy This technology introduces recombinant adeno-associated virus (rAAV) vectors engineered to enable precise, regulated expression of therapeutic genes. Recombinant viruses can deliver therapeutic gene expression constructs...
Published: 1/20/2026   |   Inventor(s): Eric Wang, John (Andy) Berglund, Elizabeth Delgado, Jana Jenquin, Derek Muscato, Ona McConnell, Leanne Adams, Maria Valero Quiros
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics, Technology Classifications > Research Tools > Therapeutics
Nature-inspired Functionally-graded UHMWPE + Kevlar Composites Achieve Extraordinarily High Strength
Nature-inspired polymers are achieved using unique processing to yield functional gradient composites with embedded Kevlar fibers exhibiting extraordinarily high strength lightweight UHMWPE materials. Background: Demand for new energy absorption materials and implantable polymeric biomaterials has increased significantly in recent years. The...
Published: 11/18/2025   |   Inventor(s): Shenqiang Ren, Lu An
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology, Technology Classifications > Engineering
Synthetic Proteins for Muscular Dystrophy Treatment
Displace or Replace Mutant MBNL Proteins that Cause Repeat Expansion DiseasesThis synthetic muscleblind-like (MBNL) protein can displace or replace the mutations that cause repeat expansion diseases, such as myotonic muscular dystrophy and spinocerebellar ataxia. Repeat expansion mutations cause more than 20 types of neurological diseases, including...
Published: 1/20/2026   |   Inventor(s): Melissa Hale, John (Andy) Berglund
Keywords(s): Myotonic Dystrophy, Protein, synthetic gene
Category(s): Technology Classifications > Human Health Care > Therapeutics
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024   |   Inventor(s): Soung Chang Liew, Lu LU, Lizhao You
Keywords(s): Network Coding, Wireless Local Area Network
Category(s): Information and Communications Technology