Search Results - jingwei+zhao

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This invention relates to designs of a low-cost scattering-based light sheet microscope that provides microscopic images of human tissue in vivo. The key idea is to use an incoherent line light source with a rectangular aperture to generate light sheet illumination and detect the scattered light from the illuminated tissue plane to generate images....

Published: 4/2/2024 | Inventor(s): Dongkyun Kang, Jingwei Zhao, Eric Yang

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry

Identification and Use of Heterocyclic Alcohol Compounds for the Treatment of SULT1A1-expressing Cancers

This technology includes the identification and use of heterocyclic alcohol compounds, including RITA and N-BIC, for the treatment of SULT1A1-expression cancers. A high-throughput screen (qHTS) was performed using >1,000 caner cell lines identified a compound called YC-1 (also called Lificiguat) that is effective across cancer cell types that express...

Published: 10/28/2024 | Inventor(s): Min Shen, Ke Kong, Toble Lee, Samarjit Patnaik, Olivia Lee, Jonathan Shrimp, Mindy Davis, Juan Marugan, Wei Zhao, Matthew Hall

Keywords(s): Agents, Alcohol, anti-cancer, Class, compounds, HETEROCYCLIC, SULT1A1-dependent, VCXXXX, WKXXXX, XCXXXX, XEXXXX

Category(s): Application > Research Materials, Application > Therapeutics, Application > Diagnostics, TherapeuticArea > Oncology

A Nanoparticle Delivery System for Treatment of Glomerular Diseases

Competitive Advantages Site-specific precise treatment for glomerular diseases High local therapeutic efficiency Minimized systemic side effects Summary Glomerulonephritis is a group of inflammatory diseases that damage the filters of the kidney, glomeruli. Glomerulonephritis requires aggressive immunosuppressive therapy, but unfortunately most...

Published: 1/22/2024 | Inventor(s): Ruisheng Liu, Samuel Wickline, Jin Wei, Hua Pan, Jie Zhang

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Category(s): Technology Classifications > Medical, Technology Classifications > Medical > Pharmaceuticals

DNA Nanocaged Enzymes

Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...

Published: 2/23/2023 | Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao

Keywords(s): Bioanalysis, Catalysis, Enzymes

Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors

Methods and Apparatus for High-Resolution Tissue Microscopy

This technology is a new type of microscope that allows for rapid diagnosis of skin lesions on a person’s body without the need for invasive procedures. This technology further advances noninvasive skin microscopy techniques, providing a solution that increases diagnostic accuracy and reduces time to diagnose. It can be used on its own or in...

Published: 6/6/2024 | Inventor(s): Dongkyun Kang, Jingwei Zhao, Clara Curiel

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics > Medical Imaging

Controlled Vapor-phase ion-gating (VPIG) and ion capping of Nanomaterials

INV-17050 Background The investigation of charged particles is a fundamental aspect of several disciplines including physics, astronomy, atmospheric science, and geophysics, and, in addition to ion gauge based pressure metrology, forms a critical component of numerous advanced applications such as mass spectroscopy, plasma acceleration, oncology,...

Published: 9/10/2024 | Inventor(s): Swastik Kar, Ji Hao, Daniel Rubin, Yung Joon Jung

Keywords(s): Carbon nanotubes, nanoparticles

Category(s): -Materials, -Nanotechnology, Technology Classifications > 2. Physical Science > Electronics/Semiconductors

Vapour-phase gating induced single-ion detection in graphene and single-wall carbon nanotube networks

INV-17012 Background Miniaturized devices having ultrasensitive ion detection capability are useful as ion detectors in diverse applications, including detection of radioactive material or other sources of radiation, electron/ion beam calibration, monitoring of pressure or vacuum, and detection of energetic particles from outer space. Carbon nanotubes...

Published: 9/10/2024 | Inventor(s): Swastik Kar, Ji Hao, Yung Joon Jung

Keywords(s):

Category(s): -Materials, -Sensors tech

Hybrid Plasmonic Platform for Directing and Controlling Nanostructure Growth

Low-Heat, Bottom-Up Approach Can Produce Metal, Polymer or Bio-Molecule Structures for Catalysis, Biosensors, Electronic Devices and MoreThis surface plasmon mediated chemical solution deposition method uses surface plasmon resonance to deposit nanoparticles in the liquid phase at room temperature to direct and control nanostructure growth. Plasmonic...

Published: 6/27/2021 | Inventor(s): Wei Wei, Jingjing Qiu

Keywords(s): Catalysts, nanoparticle synthesis, Plasmonic, Thin Films

Category(s): Technology Classifications > Engineering > Chemical, Technology Classifications > Engineering > Materials