Search Results - jeff+houkal

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Endoscope for Analyte Consumption Rate Determination with Single Cell Resolution for In Vivo Applications
Determination of consumption/secretion rates of single-cell resolution has great potential for delivering detailed insights into early onset and development of various disease states as well as drug and stimulus response. Due the lack of sensitivity of current technologies, this information is difficult to obtain. Single cell measurements in vivo are...
Published: 2/23/2023   |   Inventor(s): Deirdre Meldrum, Laimonas Kelbauskas, Jeff Houkal, Roger Johnson, Yanqing Tian, Cody Youngbull
Keywords(s): Bio-Technology, Drug Screening, Medical Devices and Imaging, Therapeutics
Category(s): Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Imaging
Single-cell QUantitative In Situ RT-PCR (SQUIRT-PCR)
Quantitative real-time PCR (qRT-PCR) is a well-established method for amplifying DNA using fluorescent probes. Traditionally this is a step-wise process where an aliquot of the DNA to be amplified is deposited in a chamber and amplified/measured in the chamber. Current systems require significant time for sample preparation including tissue disaggregation,...
Published: 2/23/2023   |   Inventor(s): Deirdre Meldrum, Shih-Hui (Joseph) Chao, Thai Tran, Laimonas Kelbauskas, Jeff Houkal, Andrew Hatch, Weimin Gao, David Richardson
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs)
Aliquot Tray
The design patents cover an ornamental design of an aliquot tray housing PCR tubes and caps set out in a regular spacing within the confines of a microwell plate. Each PCR tube can be removed on an individual bases without affecting neighboring tubes.The design ensures improved throughput, control and flexibility in reagent handling and storage.For...
Published: 2/23/2023   |   Inventor(s): Jeff Houkal, Jordan Yaron
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Genomic Assays/Reagents/Tools
Aliquot Tray
The design patents cover an ornamental design of an aliquot tray housing PCR tubes and caps set out in a regular spacing within the confines of a microwell plate. Each PCR tube can be removed on an individual bases without affecting neighboring tubes.The design ensures improved throughput, control and flexibility in reagent handling and storage. For...
Published: 2/23/2023   |   Inventor(s): Jeff Houkal, Jordan Yaron
Keywords(s): Array Techs - Micro, Nano, Gen,Proteomic, Bioanalytical/Sample Reagents, Bioassay, Diagnostics, Liquid Handling and Dispensing, Medical Devices and Imaging, Polymerase Chain Reaction (PCR)
Category(s): Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Genomic Assays/Reagents/Tools, Proteomic Assays/Reagents/Tools
Quantitative, Multi-Target, Nucleic Acid Analysis Device
Loop-mediated isothermal amplification (LAMP) has great potential for sensitive and selective nucleic acid analysis in resource-limited settings. Amplifications can be easily observed via optical means such as colorimetry which combines robust performance and simple instrumentation. To date, microfluidic approaches based on colorimetric detection have...
Published: 2/23/2023   |   Inventor(s): Rhett Martineau, Jeff Houkal, Shih-Hui (Joseph) Chao, Weimin Gao, Shufang Ci, Deirdre Meldrum
Keywords(s): Agriculture and Animal Science, Bio-Technology, Educational, Environmental, Medical Devices and Imaging
Category(s): Bioanalytical Assays, Chemistries & Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs)