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Search Results - disrupt
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Title
ID
Descending
Ascending
Monoclonal Antibody Against Human Alpha-5 Integrin that Does Not
Disrupt
Adhesive Function
This technology includes a rat monoclonal antibody termed mAb11 was generated against the human alpha-5 integrin subunit and can provide immunological characterizations without
disrupt
ing integrin adhesive function. It permits characterization of its localization even if the receptor is bound to its fibronectin ligand. The antibody is commercially available...
Published: 12/26/2024
|
Inventor(s):
Steven Akiyama
,
Susan Yamada
,
Kenneth Yamada
Keywords(s):
Against
,
Alpha-5
,
ANTIBODY
,
DISRUPT
,
DOES
,
FUNCTION
,
Human
,
INTEGRIN
,
monoclonal
,
That
,
WIXXXX
,
XAXXXX
Category(s):
Application > Research Materials
,
ResearchProducts > Antibodies
,
TherapeuticArea > Immunology
Generation of mutant mouse alleles that functionally
disrupt
production of BDNF from its ndividual promoters
This technology relates to a mouse model that improves an existing method of
disrupt
ing the production of the BDNF protein in specific parts of the brain. A current avenue of research seeks to examine how gene expression may effect long-lasting changes in the nervous system. Previous work has resulted in a mouse line in which the production of BDNF...
Published: 10/28/2024
|
Inventor(s):
Keri Martinowich
Keywords(s):
ALLELES
,
AXXXXX
,
BDNF
,
DISRUPT
,
FUNCTIONALLY
,
Generation
,
Indiividual
,
Mouse
,
MUTANT
,
NC4XXX
,
NCXXXX
,
production
,
PROMOTERS
,
That
,
VEXXXX
,
WIXXXX
,
XEXXXX
Category(s):
TherapeuticArea > Neurology
,
Application > Research Materials
,
Application > Therapeutics