Search Results - erica+wilson-rapolla

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Cutting Needle Holder (Case No. 2024-120)

Intro Sentence: Researchers from the UCLA Jules Stein Eye Institute have developed a novel multi-use surgical instrument for improved oculoplastic surgical outcomes. Background: Oculoplastic surgeries are very common in the United States, with approximately 325,000 blepharoplasties alone performed annually. Suturing during this procedure requires...

Published: 10/4/2024 | Inventor(s): Taras Gout, Erin Napier, Robert Goldberg, Maria Quintero, Ethan Osias, Erica Wilson-Rapolla

Keywords(s): biomedical implantation, Invasiveness Of Surgical Procedures, Medical Device, Medical Devices and Materials, Ophthalmology, Preclinical surgical innovation, Surgical Instrument, surgical mesh, surgical oncology, Surgical Suture , surgical tool, Surgical Tools, wearable medical device, wearable medical devices

Category(s): Medical Devices, Medical Devices > Surgical Tools

HLA-Inception: MHC-Peptide Binding Prediction

Major histocompatibility complex class I (MHC-I) molecules are principal components of immune recognition. Peptide binding to MHC-I molecules is necessary for antigen presentation and T cell recognition. Understanding and predicting MHC-I binding has great utility in T cell therapies, vaccine development and treatment of complex human diseases. Unfortunately,...

Published: 10/10/2024 | Inventor(s): Eric Wilson, Abhishek Singharoy, Karen Anderson, John Cava

Keywords(s):

Category(s): Applied Technologies, Computing & Information Technology, Cancer, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools

Prediction Algorithm for MHC-bound Peptides & SARS-CoV-2 Peptides for Vaccines

T cell immunity is a fundamental component of the immune response to infections, cancer, and autoimmunity and is strongly impacted by polymorphisms in major histocompatibility complex (MHC) protein sequences. In particular, allelic MHC-I protein variants have been shown to influence patient outcomes to various viral infections, including SARS-CoV. While...

Published: 3/10/2023 | Inventor(s): Karen Anderson, Abhishek Singharoy, Eric Wilson

Keywords(s):

Category(s): Computing & Information Technology, Coronavirus, COVID-19, Life Science (All LS Techs), Pharmaceuticals, Vaccines/Antimicrobials, SARS-CoV-2, Proteomic Assays/Reagents/Tools, Intelligence & Security