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Search Results - enzyme%2fprotein
10
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Whole-Animal Genetic Model to Mimic Aspects of the Patient Phenotype of Classic Galactosemia
Application An animal model for studying the underlying causes of galactosemia and screening for novel drugs to treat the condition. Key Benefits The first animal model for elucidating the underlying causes of galactosemia in infants. Animals with galactosemia causing genetic knockout exhibit similar disease phenotypes and complications...
Published: 7/30/2024
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Inventor(s):
Judith Fridovich-Keil
Keywords(s):
Animal Model
,
Enzyme/Protein
,
Genetic Disorders
,
Metabolic Diseases
,
Rare/Orphan Diseases
Category(s):
TechPub Algolia > Research Tools
Strategy to Identify miRNAs for Disease Diagnosis
Application Method to measure precursor and mature miRNA specifically. Key Benefits Unique primers can specifically identify miRNAs and precursor miRNAs by standard qRT-PCR without the requirement for an additional detection probe. Allows for amplification and quantification of both mature miRNA and precursor miRNAs. Potential technology to evaluate...
Published: 9/26/2024
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Inventor(s):
Wenming Li
Keywords(s):
Enzyme/Protein
,
Neuroscience/Pain
,
Oncology
Category(s):
TechPub Algolia > Research Tools
TaqMan Array Cards for Pneumococcal Detection and Serotyping
ApplicationDiagnostic for identifying Streptococcus pneumonia serotypes.Key BenefitsAllows for rapid detection and serotype identification of Streptococcus pneumonia infections.Market SummaryStreptococcus pneumonia (Spn) is a gram-positive bacteria and significant human pathogen responsible for most pneumonia cases. Typically, Spn resides asymptomatically...
Published: 7/30/2024
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Inventor(s):
Jorge Vidal Graniel
,
Fuminori Sakai
,
Lesley McGee
,
Velusamy Srinivasan
Keywords(s):
Enzyme/Protein
,
Microbiology/Infectious Diseases
Category(s):
TechPub Algolia > Diagnostics
Therapeutic Target for Hepatic Fibrosis
ApplicationPeriostin as a therapeutic target for liver disease.Key BenefitsNew therapeutic target for preventing fibrosis from entering cirrhosis stage.Therapeutic target may be used for identifying new therapy for fibrosis.Market SummaryCirrhosis is a condition in which the liver is unable to function normally due to chronic, or long lasting, injury....
Published: 11/20/2024
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Inventor(s):
Frank Anania
,
Pradeep Kumar
Keywords(s):
Enzyme/Protein
,
Hepatology
,
Immunology/Inflammation
,
Target
Category(s):
TechPub Algolia > Therapeutics
,
TechPub Algolia > Drug Discovery
Targeting Peptide Improves Accurate Myocarditis Imaging and Diagnosis
ApplicationTargeting peptide molecule for image-based diagnosis of myocarditis.Key BenefitsEnables noninvasive diagnosis of myocarditis.Targets and binds to biomarker of myocarditis.Market SummaryMyocarditis is an inflammation of the heart muscle (myocardium). Myocarditis can affect your heart muscle and your heart's electrical system, reducing the...
Published: 7/30/2024
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Inventor(s):
Michael E. Davis
,
Mario Martinez
Keywords(s):
Biomarker
,
Cardiovascular
,
Enzyme/Protein
,
Imaging
,
Target
Category(s):
TechPub Algolia > Diagnostics
Bioluminescent Ion Indicator Proteins
ApplicationFusion protein for non-invasive assessment of chloride fluctuations in neuronal processes.Key BenefitsEnables a non-invasive method of imaging chloride in animals.Offers high signal-to-noise ratio compared to fluorescent light.Market SummaryNeuronal chloride (Cl-) is involved in many normal neurophysiological activities, including synaptic...
Published: 11/20/2024
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Inventor(s):
Robert E. Gross
,
Ken Berglund
,
Jack Tung
Keywords(s):
Biomarker
,
Enzyme/Protein
,
Imaging
,
Neuroscience/Pain
Category(s):
TechPub Algolia > Research Tools
Compound and Method to Explore and Prepare O-Glycans from Living Cells
ApplicationChemical compound and method that enables detection of O-glycans with higher sensitivity than conventional approaches.Key BenefitsHigher accuracy and sensitivity than current β-elimination method.Smaller sample quantities required compared to traditional mass spectrometry.Method promotes the discovery of novel glycans and study of cellular...
Published: 9/26/2024
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Inventor(s):
Tongzhong Ju
,
Richard Cummings
,
Matthew Kudelka
Keywords(s):
Biomarker
,
Enzyme/Protein
Category(s):
TechPub Algolia > Diagnostics
,
TechPub Algolia > Research Tools
High Temperature Bacterial Expression Vector for Protein/Peptide Manufacturing
Application Plasmid for the expression and production of non-native proteins in Geobacillus stearothermophilus at high temperatures. Key Benefits Allows for improved manufacturing of peptides & proteins at higher temperatures than generally possible. High incubation temperature prevents contamination with other bacterial species. Market...
Published: 11/20/2024
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Inventor(s):
Ichiro Matsumura
,
Kristen Blanchard
Keywords(s):
Enzyme/Protein
Category(s):
TechPub Algolia > Research Tools
,
TechPub Algolia > Drug Discovery
Innovative Method for Bulk Production of Sphingolipids
ApplicationOptically pure D-erythro-Sphingosine that can be produced with high yield.Key Benefits Method efficiently produces D-erythro-Sphingosine and derivatives in bulk and with high optical purity. D-erythro-Sphingosine can be converted to many other sphingolipids for use in the production of therapeutics and cosmetics. Technical Summary Sphingolipids...
Published: 12/4/2024
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Inventor(s):
Hao Yang
,
Lanny Liebeskind
Keywords(s):
Enzyme/Protein
,
Microbiology/Infectious Diseases
,
Oncology
Category(s):
TechPub Algolia > Therapeutics
,
TechPub Algolia > Drug Discovery
,
TechPub Algolia > Research Tools
Cytotoxicity-Based Genetic Selection for Targeted Drug Screening
Applications Screening method for drug discovery and investigating protein-protein interactions. Technical Summary Drug discovery is typically dependant on screening methods that involve negative selection, or the death of cell cultures when exposed to a specific drug. This invention, a cytoxicity-based genetic selection method (TOXSEL), introduces...
Published: 10/17/2024
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Inventor(s):
Raymond (Ray) Dingledine
,
John Collier
,
Haian Fu
Keywords(s):
Enzyme/Protein
Category(s):
TechPub Algolia > Drug Discovery