Search Results - diagnostic+markers+%3e+immunology

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An Acoustic Device for Large Area Single Cell Trapping and Selective Release (Case No. 2025-047)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an acoustic microfluidic platform that offers a cost-effective and practical approach for handling individual cells at the microscale. Background: Single-cell manipulation is essential for understanding cellular behavior, disease progression, and therapeutic...
Published: 1/13/2026   |   Inventor(s): Pei-Yu Chiou, Xiang Zhang
Keywords(s): acoustic microfluidics, acoustic potential wells, acoustics, cell proliferation, cell viability, Diagnostic Platform Technologies (E.G. Microfluidics), diagnostic platforms, Digital Microfluidics, disposable microfluidic platforms, high throughput, high throughput assays, high throughput testing, High-Content Screening, high-throughput cell handling, low-cost fabrication, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared laser, photolithography-free fabrication, research instrumentation, scalable platform, single cell analysis, single cell analysis and testing, Single cell data, single-cell handling, single-cell manipulation, single-cell resolution, single-cell trapping
Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Mechanical, Mechanical > Instrumentation, Platforms, Platforms > Diagnostic Platform Technologies
Unique Tests to Assess the Expansion and Function of Natural Killer Cells in Health and Disease (UCLA Case No. 2019-635)
UCLA researchers in the School of Dentistry have developed a unique set of tests to determine the expansion and function of natural killer cells in healthy subjects and cancer patients. BACKGROUND: Natural killer (NK) cells have the remarkable ability to target cancer stem cells (CSCs) and undifferentiated tumors. However, downregulation of NK receptors...
Published: 10/23/2025   |   Inventor(s): Anahid Jewett
Keywords(s):  
Category(s): Diagnostic Markers > Immunology, Therapeutics > Immunology And Immunotherapy, Life Science Research Tools > Cell Lines
Use of Blood, Bronchoalveolar Lavage Fluid (BALF) or Urine Cytokines Combined With Donor-Derived Cell-Free DNA (dd-cfDNA) as a Biomarker of Allograft (UCLA Case No. 2025-316)
UCLA researchers in the Department of Pulmonology have identified a novel non-invasive combinatorial biomarker for prediction, early detection, and monitoring of acute and chronic allograft injury. BACKGROUND: Post-surgery treatment and rejection surveillance for solid organ transplantation remains challenging, primarily due to a limited ability to...
Published: 10/3/2025   |   Inventor(s): Yusaku Shino
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Platforms > Diagnostic Platform Technologies
Antiviral Compounds Inhibiting Zika Virus (ZIKV), and Methods and Zika Treatment Thereof (UCLA Case No. 2025-241)
UCLA researchers from the Molecular and Medical Pharmacology Department and CNSI have identified antiviral compounds that effectively inhibit Zika virus infection and cytopathic effects, potentially leading to improved therapeutics and treatment outcomes. BACKGROUND: Zika virus (ZIKV), a flavivirus now endemic to several regions globally, can cause...
Published: 10/3/2025   |   Inventor(s): Vaithilingaraja Arumugaswami, Robert Damoiseaux
Keywords(s):  
Category(s): Life Science Research Tools > Screening Libraries, Diagnostic Markers > Immunology, Diagnostic Markers > Targets And Assays, Therapeutics > Infectious Diseases, Therapeutics > CNS and Neurology, Therapeutics > Immunology And Immunotherapy, Platforms > Diagnostic Platform Technologies
Hemodynamics Driven Magnetoelastic Vascular Graft (Case No. 2025-124)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel magnetoelastic vascular graft to provide real-time, wireless, and continuous stenosis monitoring. TITLE: Hemodynamics Driven Magnetoelastic Vascular Graft Background: Vascular grafts are commonly used to restore blood flow in patients with blocked or damaged blood...
Published: 11/6/2025   |   Inventor(s): Jun Chen, Song Li, Guorui Chen
Keywords(s): cardiovascular monitoring, Diagnostic Platform Technologies (E.G. Microfluidics), hemodynamic monitoring, Hemodynamics, magnetoelastic sensor, Medical diagnostics, Vascular therapy
Category(s): Diagnostic Markers > Immunology, Life Science Research Tools > Screening Libraries, Medical Devices > Monitoring And Recording Systems, Therapeutics > Autoimmune, Therapeutics > Immunology And Immunotherapy, Therapeutics > Transplant, Therapeutics > Hematology, Therapeutics > Cardiovascular
Saliva Anti-SSA/Ro IgA1 Differentiates Sjögren’s from Non-Sjögren’s Syndrome Patients (UCLA Case No. 2023-292)
UCLA researchers in the Department of Dentistry have developed a novel methodology to accurately differentiate patients with Sjögren’s Disease from non-Sjögren’s Disease patients by monitoring saliva IgA1 forms, enabling more accurate tracking of disease progression. BACKGROUND: The presence and detection of autoantibodies within...
Published: 7/17/2025   |   Inventor(s): David Wong
Keywords(s):  
Category(s): Therapeutics > Autoimmune, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Therapeutics > Ophthalmology
Interferon Activation Score Is a Biomarker for Immunotherapy in Malignant Glioma Patients (UCLA Case No. 2024-043)
UCLA researchers from the Department of Neurosurgery have characterized immune responses in malignant glioma patients receiving immunotherapy to develop a robust biomarker that will allow prediction of clinical outcomes following treatment. BACKGROUND: Malignant gliomas are the most common primary brain tumors in adults. No cures exist and most gliomas...
Published: 7/31/2025   |   Inventor(s): Robert Prins
Keywords(s): adjuvant therapy, Biomarker, Chemotherapy, Clinical Trial, dendritic cell vaccination, Glioblastoma, Glioma, immune response, Immunotherapy, interferon, malignant glioma
Category(s): Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Oncology, Therapeutics > CNS and Neurology
Control of Periprosthetic Joint Infections (Case No. 2021-334)
Summary: UCLA researchers in the Department of Orthopaedic Surgery have developed a non-invasive method to disrupt biofilms on orthopaedic implants and decrease the overall rate of infections. Background: Prosthetic joint infection (PJI) remains a serious complication in hip and knee arthroplasty, with skyrocketing revision rates across all orthopaedic...
Published: 2/14/2025   |   Inventor(s): Fabrizio Billi, Beth Lazazzera
Keywords(s): Biofilm, Cell Growth, electromagnetic, Infection, Nanoparticle, Orthopaedics, Orthopedics and Prosthetics (O & P), Osteo, Prosthetics
Category(s): Medical Devices > Prosthetics, Chemical > Coatings, Adhesives & Inks, Diagnostic Markers > Immunology, Materials > Membranes, Medical Devices > Coatings, Therapeutics > Orthopaedics
Affinity and Functional Based Screening of T Cell Receptor Repertoire Using Nanovials (Case No. 2024-042)
Summary: Researchers in the Department of Bioengineering at UCLA have developed a hydrogel platform that measures single T cell secretions, aiding in the definition of T cell receptor repertoires for functional immunotherapy applications. Background: T cell immunotherapies, namely T cell receptor (TCR) therapies, have emerged as promising candidates...
Published: 4/14/2025   |   Inventor(s): Dino Di Carlo, Owen Witte, Doyeon Koo, Zhiyuan Mao
Keywords(s): Cancer Immunotherapy, CAR-T cell therapy, Flow Cytometry, hydrogel, Immunooncology, Immunotherapy, Peptide, single cell analysis, T Cell, T cell based therapy
Category(s): Diagnostic Markers > Immunology, Life Science Research Tools > Screening Libraries, Therapeutics > Immunology And Immunotherapy
A Method and System for Pre-processing Medical Images (Case No. 2024-177)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a novel pre-processing computer algorithm for automated medical imaging. Background: The integration of machine learning and artificial intelligence into medical imaging applications offers significant potential to automate the diagnosis of various...
Published: 2/14/2025   |   Inventor(s): Bahram Jalali, Callen MacPhee, Yiming Zhou, Koichiro Kishima
Keywords(s): 3D ultrasound imaging, Artificial Intelligence, bioimaging, Computer Vision, histopathology images, Machine Learning, Medical Imaging, MRI, X-Ray
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Immunology, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Software & Algorithms > Image Processing
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