Search Results - chung-wei+lin

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Improved Methods For Cryopreservation Of Cells, Tissues, And Organs
Summary: The National Eye Institute seeks research co-development partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...
Published: 9/9/2024   |   Inventor(s): Jingxing Ou, Kiyoharu Miyagishima, Guanghui Jin, Wei Li, Lihao Ge
Keywords(s):  
Category(s): Application, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Eye / Ear / Nose / Throat
Biomimetic high-strength bone implant polymer material
Problem Bone defects are a global issue affecting millions, caused by factors such as trauma, aging, disease, surgical resections, and congenital abnormalities. There are natural and synthetic options for bone grafts or replacement. A natural bone graft may come from the patient or a donor and is surgically inserted and provides a surface for the remaining...
Published: 4/12/2024   |   Inventor(s): Wei Li, Hanyu Zhu, Vincent Wang
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Therapeutics > Synthetic biology
Knitted strain sensor for pharyngeal rehabilitation
Problem Dysphagia, or swallowing dysfunction, affects 9.5 million people in the United States. Dysphagia poses significant risks including malnutrition, dehydration, aspiration pneumonia, and death. Dysphagia is associated with diseases including stroke, muscular dystrophy, and throat cancer. The impact of dysphagia extends beyond physical discomfort,...
Published: 2/15/2024   |   Inventor(s): Jonathan Chen, James Sulzer, Corinne Jones, David Zhang, Drake Rowland, Wei Li
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Diagnostic
Nutraceuticals for Preventing Leaky Gut
​ ​ Image Legend: Control intestinal organoids and organoids conditioned to have a leak, or more permeable barrier, were treated with nutraceuticals which clearly prevented increased permeability in the “leaky” organoids. Similar findings were observed in cell culture and in vivo Invention Summary: More than 22 million Americans...
Published: 10/21/2024   |   Inventor(s): Ronaldo Ferraris, Nan Gao, Wei Li
Keywords(s):  
Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics
Strategies to Protect Mammalian Neural Tissue Against Cold and Potentially Other Metabolic Stresses and Physical Damages
Abstract: Researchers at the National Eye Institute (NEI) have discovered an invention describing a composition and method(s) of using such composition for preserving viability of cells, tissues, or organs at a low temperature (around 4ºC). Current cold storage solutions or methods for cells, tissues, and organs are suboptimal due to irreversible...
Published: 4/8/2024   |   Inventor(s): Jingxing Ou, Wei Li, Kiyoharu Miyagishima
Keywords(s): Cold Storage, Cold-sensitive, Hypothermia, lysosome, Mitochondria, National Eye Institute, NEI, neural injury, Ou, Protein Degradation, TRANSPLANTATION
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Cardiology, Application > Research Materials, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, TherapeuticArea > Nephrology
Establishment of Induced Pluripotent Stem Cells (iPSC) from the Thirteen-lined Ground Squirrel
Abstract: The limited choice in cell types available for in vitro studies has become an obstacle in hibernation research. Researchers at the National Eye Institute for the first time have successfully established iPSC line(s) from a mammalian hibernator, which can be potentially used to generate various cell types and tissue models for in-depth mechanistic...
Published: 4/8/2024   |   Inventor(s): Jingxing Ou, Barbara Mallon, Wei Li
Keywords(s): cellular stress, coldness, hibernation, Induced Pluripotent Stem Cell (iPSC), Li, neural injury, Squirrel
Category(s): Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Neurology
Self-neutralizing air-breathing thruster and method of neutralization
An ion-engine is the cutting edge for atmospheric air-breathing engines. The technology depends on ionizing and neutralizing atmospheric air particles which create thrust. This unique possibility makes it an ideal choice for very-low-orbit satellites. Very- low-orbit satellite capabilities have benefits such as higher resolution for images, weight...
Published: 7/30/2024   |   Inventor(s): Michael Keidar, Anmol Taploo, Li Lin
Keywords(s):  
Category(s): Technology Classifications > Computers Electronics & Software, Technology Classifications > Computers Electronics & Software > Aviation, Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment, Technology Classifications > Industrial or Consumer Tech > Industrial Manufacturing
Cooperative Driving of Connected Autonomous Vehicles Using Responsibility-Sensitive Safety Rules
­Background Connected Autonomous Vehicles (CAVs) are expected to enable reliable and efficient transportation systems. Most cooperative driving approaches for CAVs and motion planning algorithms for multi-agent systems are not completely safe because they implicitly assume that all vehicles/agents will execute the expected plan within a small margin...
Published: 2/23/2023   |   Inventor(s): Mohammad Khayatian, Mohammadreza Mehrabian, Harshith Allamsetti, Kai-Wei Liu, Po-Yu Huang, Chung-Wei Lin, Aviral Shrivastava
Keywords(s):  
Category(s): Wireless & Networking, Physical Science, Computing & Information Technology, Intelligence & Security
Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors
Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...
Published: 7/30/2024   |   Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman
Keywords(s):  
Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
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