Search Results - jingxing+ou

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Improved Methods For Cryopreservation Of Cells, Tissues, And Organs
Summary: The National Eye Institute seeks research co-development partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...
Published: 9/9/2024   |   Inventor(s): Jingxing Ou, Kiyoharu Miyagishima, Guanghui Jin, Wei Li, Lihao Ge
Keywords(s):  
Category(s): Application, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Eye / Ear / Nose / Throat
Strategies to Protect Mammalian Neural Tissue Against Cold and Potentially Other Metabolic Stresses and Physical Damages
Abstract: Researchers at the National Eye Institute (NEI) have discovered an invention describing a composition and method(s) of using such composition for preserving viability of cells, tissues, or organs at a low temperature (around 4ºC). Current cold storage solutions or methods for cells, tissues, and organs are suboptimal due to irreversible...
Published: 4/8/2024   |   Inventor(s): Jingxing Ou, Wei Li, Kiyoharu Miyagishima
Keywords(s): Cold Storage, Cold-sensitive, Hypothermia, lysosome, Mitochondria, National Eye Institute, NEI, neural injury, Ou, Protein Degradation, TRANSPLANTATION
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Cardiology, Application > Research Materials, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, TherapeuticArea > Nephrology
Establishment of Induced Pluripotent Stem Cells (iPSC) from the Thirteen-lined Ground Squirrel
Abstract: The limited choice in cell types available for in vitro studies has become an obstacle in hibernation research. Researchers at the National Eye Institute for the first time have successfully established iPSC line(s) from a mammalian hibernator, which can be potentially used to generate various cell types and tissue models for in-depth mechanistic...
Published: 4/8/2024   |   Inventor(s): Jingxing Ou, Barbara Mallon, Wei Li
Keywords(s): cellular stress, coldness, hibernation, Induced Pluripotent Stem Cell (iPSC), Li, neural injury, Squirrel
Category(s): Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Neurology
Topical Application of Hydrogel for the Treatment of Acute Spinal Cord Injury
This hydrogel can be used for the non-invasive treatment of acute spinal cord injuries by applying topically to the injury site. According to the Centers for Disease Control and Prevention, about 450,000 people in the United States are currently living with a spinal cord injury and 12,000 new cases develop each year. The cost of rehabilitation and on-going...
Published: 2/14/2023   |   Inventor(s): Xing Jin, Vibhor Krishna, Xuejun Wen, Ning Zhang
Keywords(s): Biomaterials - Neurology, Drugs/Pharma - Drug Delivery, Molecular Therapies, Regenerative Medicine, Tissue Engineering
Category(s): Biomedical Sciences