Search Results - chuan+he

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Novel Lipid Lowering, Anti-Atherosclerosis and Anti-Obesity Effects of Netrin-1 (UCLA Case No. 2019-728)
UCLA researchers in the Department of Anesthesiology have developed a novel and extremely robust lipid lowering, anti-atherosclerotic, and anti-obesity treatment with Netrin-1.BACKGROUND:Hyperlipidemia, an elevation of different forms of lipids in the bloodstream, is the most important risk factor for coronary heart disease, while causing many other...
Published: 3/26/2026   |   Updated: 3/26/2026   |   Inventor(s): Hua Cai
Keywords(s): Cardiovascular, Hematology, Therapeutics & Vaccines
Category(s): Therapeutics > Cardiovascular, Therapeutics > Hematology
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 3/23/2026   |   Updated: 3/23/2026   |   Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Updated: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Exploiting Vulnerabilities and Security Threats in Retrieval-Augmented Generative Models: The LIAR Attack Framework
Invention Description Retrieval-Augmented Generative (RAG) models boost generative AI’s accuracy by connecting large language models (LLMs) with the most current, external, knowledge sources. RAG models are widely used in fact-checking, information retrieval, and AI-driven search engines. Despite their utility, adversarial threats can exploit...
Published: 2/26/2026   |   Updated: 1/30/2026   |   Inventor(s): Zhen Tan, Chengshuai Zhao, Raha Moraffah, Huan Liu
Keywords(s): Artificial Intelligence, Data Mining, Large Language Models, Machine Learning, Natural Language Processing
Category(s): Artificial Intelligence/Machine Learning, Cybersecurity, Computing & Information Technology, Intelligence & Security, Physical Science
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 3/20/2026   |   Updated: 10/24/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
CBLs as a biomarker of and target to treat systemic lupus erythematosus (SLE)
SLE DIAGNOSTIC TOOL CBL protein levels used as a molecular diagnostic marker to diagnose and assess severity of Systemic Lupus Erythematosus (SLE) Systemic Lupus Erythematosus patient (photo: NCRD) UNMET NEED Systemic Lupus Erythematosus (SLE) is an autoimmune disease, especially prevalent in women, and without curative treatment. In addition,...
Published: 2/26/2026   |   Updated: 9/9/2025   |   Inventor(s): Hua Gu
Keywords(s): Innovation
Category(s): Applications > Soins et santé > Diagnostic, English Applications > Health and care > Diagnostic-ENG, Secteurs > Sciences de la vie, Sectors > Life sciences, Objectifs de Développement Durable > ODD 03 : Bonne santé et bien-être, Sustainable Development Goals > Goal 03: Good Health and Well-Being
Exploiting Class Probabilities for Black-Box Sentence-Level Attacks
Background Text classification models have become increasingly prevalent in cybersecurity applications, but remain susceptible to adversarial examples (e.g., carefully crafted sentences with human-unrecognizable changes to the inputs, that are misclassified). Adversarial attacks provide profound insights into the classifiers’ vulnerabilities,...
Published: 2/26/2026   |   Updated: 8/21/2025   |   Inventor(s): Raha Moraffah, Huan Liu
Keywords(s): Machine Learning, Natural Language Processing, Red teaming, Security
Category(s): Physical Science, Applied Technologies, Artificial Intelligence/Machine Learning, Cybersecurity
Chip-based Nano-optoelectrodes for Optical Voltage Sensing
THE CHALLENGE The challenge in developing reliable, scalable optical voltage sensors lies at the intersection of technical complexity and commercial viability. Current solutions—ranging from fluorescent dyes to random plasmonic nanostructures—face critical limitations: they either require invasive labeling, suffer from photobleaching,...
Published: 10/22/2025   |   Updated: 7/3/2025   |   Inventor(s): Yuming Zhao, Chuan Xiao, Wei Zhou
Keywords(s):  
Category(s): Technology Classifications > Electronics
Adversarial Text Purification: Large Language Model Approach for Defense
Background Adversarial purification is a defense mechanism for safe-guarding classifiers against adversarial attacks without knowing the type of attacks or training of the classifier. These techniques analyze and eliminate adversarial perturbations from the attacked inputs, and help to restore purified samples that retain similarity to the attacked...
Published: 2/26/2026   |   Updated: 6/27/2025   |   Inventor(s): Raha Moraffah, Shubh Khandelwal, Amrita Bhattacharjee, Huan Liu
Keywords(s): Artificial Intelligence, Defense Applications, Machine Learning, Natural Language Processing, Security, Text Mining
Category(s): Physical Science, Artificial Intelligence/Machine Learning, Applied Technologies, Cybersecurity
Methods and Systems for Detecting Disinformation Generated by Large Language Models
Background The rapid dissemination of news is an important factor for the global population to stay up to date with current events, or to make well-informed decisions in dynamic sectors like the stock market. Journalists typically include large amounts of quantitative information using data visualization to help enhance accessibility and comprehension...
Published: 2/26/2026   |   Updated: 6/17/2025   |   Inventor(s): Bohan Jiang, Zhen Tan, Ayushi Nirmal, Huan Liu
Keywords(s): Data Mining, Disinformation, Large Language Model, Machine Learning
Category(s): Cybersecurity, Physical Science, Artificial Intelligence/Machine Learning
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