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RNA-aptamer-mediated Bacteriophage Purification

A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...

Published: 4/1/2025 | Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen

Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

Production of Cyclic Macrocycle Library for Rapid High Throughput Evaluations in Aqueous Medium

Produces cyclic peptide libraries quickly, cheaply, and without the need of purification. Background: Cyclic peptides are a class of molecules with important biological activities that could provide substantial medical benefit. Cyclic peptides are often used to develop therapeutic agents and biochemical tools. Unfortunately, the most common method...

Published: 4/1/2025 | Inventor(s): Qiang Zhang, Huan Chen

Keywords(s): Technologies

Category(s): Campus > University at Albany, Technology Classifications, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Materials and Chemicals, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 3/4/2025 | Inventor(s): Yong Zeng, He Yan

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

Anti-Thrombin Nanoparticles and Therapeutics to Treat Necrotizing Enterocolitis

Advantages: Bivalirudin-tagged nanoparticles bind and neutralize nascent thrombin in clots, minimizing systemic anticoagulant effects Anti-thrombin nanoparticle confines its anticoagulant activity to sites of clot formation, limiting excessive systemic coagulation inhibition Dual therapeutic and diagnostic potential allows clinicians to treat NEC...

Published: 2/5/2025 | Inventor(s): Akhil Maheshwari, Samuel Wickline, Koppenruncholan Namachivayam, Hua Pan

Keywords(s): Gastrointestinal / Digestive Health, Pharmaceuticals

Category(s): Technology Classifications > Medical > Pharmaceuticals

Chip-integrated Nanolaminate Nano-optoelectrode Arrays for Interfacial Electrochemical Reaction Monitoring

THE CHALLENGE: In the field of electrochemistry, understanding the dynamics of interfacial reactions is crucial for advancements in areas such as electrocatalysis, biosensing, and energy conversion. Real-time monitoring of these reactions allows scientists to gain insights into mechanisms that drive these processes. Accurate and detailed analysis of...

Published: 4/2/2025 | Inventor(s): Yuming Zhao, Chuan Xiao, Wei Zhou

Keywords(s):

Category(s): Technology Classifications > Chemicals/Materials

Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations

The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...