Search Results - cancer%2foncology

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New Lipiodol Formulation for Treating Hepatocellular Carcinoma with Transarterial Chemoimmunoembolization
NU 2021-148 INVENTORS Dong Hyun Kim* Heegon Kim SHORT DESCRIPTION A new Lipiodol formulation designed to improve the efficacy and safety of transarterial chemoembolization in combination with immunotherapy. BACKGROUND Transarterial chemoembolization...
Published: 9/4/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Drug delivery, Gastrointestinal and Hepatic disease, Immunotherapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Therapy for T-Cell Lymphoma
INVENTORS Jaehyuk Choi* Jay Daniels Jurgen Ruland Tim Wartweig SHORT DESCRIPTION Targeting PD-1 related mechanisms for treatment of aggressive T-Cell lymphomas BACKGROUND T-cell non-Hodgkin lymphomas (T-NHLs) are highly aggressive cancers that can be resistant to chemotherapies. The molecular pathogenesis of these cancers remains ill defined....
Published: 8/14/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Small molecule
Category(s): Life Sciences > Therapeutics
New Targets and Methods for Treating Pulmonary Hypertension and Cardiomyopathy
LU 2020-120, LU 2021-119, LU 2021-191 INVENTOR Youyang Zhao* SHORT DESCRIPTION New targets and methods for treating pulmonary hypertension, cardiomyopathy, and heart failure. BACKGROUND Pulmonary hypertension (PH) and cardiomyopathy are deleterious diseases often characterized by excessive vasoconstriction or abnormal vascular-ventricular...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Cardiology and Cardiovascular disease, Pulmonary disease, Therapeutics
Category(s): Life Sciences > Therapeutics
A New Adjustable Applicator for Interstitial Brachytherapy
NU 2022-153 INVENTORS Shuhua Zheng* Jonathan Strauss Eric Donnelly Jooyoung Sohn SHORT DESCRIPTION A new and improved brachytherapy applicator for treating patients with gynecological cancers. This advanced device allows for precise, visualized placement of interstitial implants to improve therapeutic outcomes. ABSTRACT Gynecologic cancers, particularly...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Medical device, Obstetric/Gynecological
Category(s): Life Sciences > Therapeutics
A method to stratify subtypes of T1 bladder cancer for targeted therapeutics
NU 2020-155 INVENTORS Joshua Meeks* A Gordon Robertson Clarice S. Groeneveld Aurélien de Reyniès SHORT DESCRIPTION Using next-generation sequencing to classify patient subtypes of bladder cancer for targeted T1 tumor therapies BACKGROUND T1 bladder cancers have the highest progression and recurrence rates of all non-muscle-invasive...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Biomarker, Cancer/Oncology, Personalized medicine, Urology
Category(s): Life Sciences > Therapeutics
Exercise Induced Myokines to Target Receptor Kinases and Chromatin Architecture
A Novel Myokine Oncology Therapeutic With Companion Drug Discovery Platform NU 2019-094 INVENTORS Hemant K. Roy Vadim Backman* SHORT DESCRIPTION Novel oncology drug discovery platform using contraction-induced myokine secretion BACKGROUND Colorectal cancer is the third most commonly diagnosed cancer and second most common cause of cancer...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Drug discovery, Personalized medicine
Category(s): Life Sciences > Therapeutics
Humanized antibody targeting the tumor associated antigen, IL13Ra2
Humanized antibody targeting the tumor associated antigen, IL13Ra2 NU 2020-031 INVENTORS Irina Balyasnikova* SHORT DESCRIPTION A novel antibody that specifically targets glioblastoma cells BACKGROUND Glioblastoma is a deadly, incurable disease with a low 5 year survival rate. The current standard of care typically involves surgical resection...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Antibody, Cancer/Oncology, CAR T, Cell therapy, Gene therapy, Neurologic disease, Personalized medicine, Research tool, Therapeutics
Category(s): Life Sciences > Therapeutics
Novel Delivery System for BMP4 for the Treatment of Pediatric High-Grade Glioma
Novel Delivery System for BMP4 for the Treatment of Pediatric High-Grade Glioma NU 2020-051 INVENTORS Samuel I. Stupp SHORT DESCRIPTION A novel delivery system for bone morphogenetic protein 4 utilizing nanotechnology. BACKGROUND Pediatric high-grade glioma (HGG) is among the most formidable cancer occurring in childhood patients. Current treatments...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Drug delivery, Drug delivery, Nanomaterials
Category(s): Life Sciences > Therapeutics
Immuno-Ablation Agent for Combination Therapy Against Solid Tumors
NU 2022-058 INVENTORS Dong Hyun Kim* Kijung Kwak Bo Yu SHORT DESCRIPTION A method of co-delivering immune modulating agents during ethanol ablation of solid tumors BACKGROUND Ethanol ablation therapy is a simple and inexpensive method commonly employed to shrink solid tumors. Like other tumor ablation techniques, such as radiofrequency ablation,...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Drug delivery, Immunotherapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Novel Approach to Attenuate Anthracycline-Induced Cardiotoxicity due to Doxorubicin
NU 2018-028 INVENTORS Paul Burridge* Tarek Magdy SHORT DESCRIPTION The use of desipramine to protect against doxorubicine-induced cardiotoxitiy BACKGROUND Doxorubicin, a cytotoxic anthracycline antibiotic, is a common anti–cancer agent used to treat a wide variety of adult and childhood cancers. The cardiotoxicity of anthracyclines, however,...
Published: 7/3/2024   |   Inventor(s):  
Keywords(s): Cancer/Oncology, Cardiology and Cardiovascular disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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