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Therapeutic Neutrophils for Cardiovascular Disease
THE CHALLENGE Treating chronic inflammatory and cardiovascular diseases like atherosclerosis has proven difficult due to the lack of precision in current therapies. While these conditions are driven by complex immune responses, existing treatments rely heavily on broad, systemic anti-inflammatory drugs that often come with unwanted side effects and...
Published: 4/14/2025
|
Inventor(s):
Liwu Li
,
Shuo Geng
Keywords(s):
Category(s):
Technology Classifications > Biomedical
,
Technology Classifications > Biotechnology
,
Technology Classifications > Pharmacology and Therapeutics
Neutrophil Subsets for the Treatment of Cancer
THE CHALLENGE Developing a cancer immunotherapy platform that can effectively and safely leverage the complex role of neutrophils—an abundant, yet highly variable, type of innate immune cell continues to prove challenging. Unlike current therapies that primarily target the adaptive immune system, an approach that must navigate the dual nature...
Published: 4/14/2025
|
Inventor(s):
Liwu Li
,
Yao Zhang
Keywords(s):
Category(s):
Technology Classifications > Biomedical
,
Technology Classifications > Biotechnology
,
Technology Classifications > Pharmacology and Therapeutics
Model Predictive Control in Laser 3D Printing
THE CHALLENGE Laser powder bed fusion (LPBF) manufacturing faces significant challenges due to its traditional reliance on empirically optimized, constant processing parameters that do not adequately address layer‐wise variations in thermal history, leading to inconsistent microstructures, porosity, poor surface finishes, and geometric distortions....
Published: 4/14/2025
|
Inventor(s):
Alexander Riensche
,
Prahalada Rao
,
Kevin Cole
Keywords(s):
Category(s):
Technology Classifications > Additive Manufacturing
,
Technology Classifications
,
Technology Classifications > Engineering
LIGHTWEIGHT OUT OF ORDER SCHEDULER FOR GPUs
Lightweight Out of Order Scheduler for GPUs Princeton Docket # 24-4
0
82-1 Graphics processing units (GPUs) accelerate parallel applications, such as machine learning and autonomous vehicles. Despite abundant parallelism in these applications, many programs still exhibit significant stalls. Previous proposals suggest adding out-of-order (OoO) execution...
Published: 4/14/2025
|
Inventor(s):
Ishita Chaturvedi
,
Bhargav Godala
,
David August
Keywords(s):
Category(s):
Computer Science and Information Technology
,
Mechanical Engineering and Robotics
Design and Use of Multi-targeting DNA Nanoswitches for Increased Sensitivity Detection of Long RNAs
This technology provides a novel method for detecting COVID-19 and potentially other virus-based diseases. Background: The COVID-19 pandemic created an unprecedented need for large scale diagnostic testing. Unfortunately, the pandemic also created a number of challenges for traditional in vitro diagnostic techniques. These challenges include reagent...
Published: 4/14/2025
|
Inventor(s):
Kenneth Halvorsen
Keywords(s):
detection
,
DNA nanoswitches
,
Sensitivity
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications
,
Technology Classifications > COVID-19
,
Technology Classifications > Diagnostics
,
Technology Classifications > Research Tools and Reagents
'Martin Irrigation Head' for Solid Set Flood Irrigation
This invention is a high flow bubbler sprinkler head and method for crop irrigation. The “Martin Irrigation Head” modifies existing solid-set sprinkler irrigation pipe by replacing the sprinkler with a new irrigation head with a modification at the base that can be used to divert water flow out of the sprinkler head or out the bottom for...
Published: 4/14/2025
|
Inventor(s):
Robert Masson
,
Donald Dinwiddie
,
Hector Munoz
,
Ethan Orr
Keywords(s):
Category(s):
Technology Classifications > Agriculture & Horticulture > Crop Improvement
,
Technology Classifications > Energy, Cleantech & Environmental > Water Resource Efficiency
Ophthalmoscopic Device and Method for Capturing Images using the Same
The invention is a low-cost, portable in-vivo confocal ophthalmoscope (PICO) designed to capture microscopic images of the anterior segment of the eye and external eye structures without direct contact. The device is compact, lightweight, and capable of providing high-resolution imaging for real-time diagnostics. This ophthalmoscope can attach to standard...
Published: 4/14/2025
|
Inventor(s):
Dongkyun Kang
,
Kenneth Marcelino
,
Momoka Sugimura
,
Jaya Chidambaram
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Lens & System Design
,
Technology Classifications > Medical Devices > Diagnostic
,
Technology Classifications > Imaging & Optics > Ophthalmology
,
Technology Classifications > Healthcare Portfolios > Ophthalmology
Method and Structure for Optical Coupling in Photonic Integrated Circuits Using Etched Silicon Substrates
This invention introduces a novel method and structure for optical coupling in photonic integrated circuits (PICs) using etched silicon substrates. These etched features allow light to be introduced from beneath the substrate and efficiently coupled into on-chip waveguides. It enhances the efficiency of photonic couplings, allowing multiple input modes...
Published: 4/14/2025
|
Inventor(s):
Mohamed ElKabbash
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Materials & Fabrication
,
Technology Classifications > Imaging & Optics > Telecommunications
,
Technology Classifications > Engineering & Physical Sciences > Photonics
Targeted, Enhanced Modification Of Lipid NanoparticlesTto Improve Tumor Therapeutic Efficacy
A method to inhibit small extracellular vesicles (sEVs) released by tumor cells to enhance lipid nanoparticle (LNP) accumulation in tumors. Problem: Lipid nanoparticles (LNPs) have shown promise as drug delivery systems for various diseases with several clinically approved products. However, their ability to deliver genes specifically to tumor cells...
Published: 4/11/2025
|
Inventor(s):
Michael Mitchell
,
Ningqiang Gong
,
Wenqun Zhong
,
Wei Guo
Keywords(s):
Bioengineering
,
Drug Delivery
,
Immunoncology
,
Oncology
Category(s):
Technology Classifications > Therapeutics
A Device for Interfacing with Biological Tissue Through the Nasal Cavity
NU 2
0
23-155 INVENTORS Gregory Lane Christina Zelano* Mahmoud Omidbeigi Andrew Sheriff Bruce Kuang-Huay Tan* SHORT DESCRIPTION A versatile multi-contact electrode device capable of measuring, recording, stimulating, and modulating electrophysiological signals within or in proximity to the nasal cavity, such as the olfactory bulb. The device...
Published: 4/11/2025
|
Inventor(s):
Keywords(s):
Category(s):
Life Sciences > Healthcare Devices, Tools & IT
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