Search Results - ziwen+li

11 Results

Sort By:

Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)

Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...

Published: 10/1/2025 | Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun

Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration

Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery

Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.

Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...

Published: 5/9/2025 | Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline

Keywords(s):

Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Heavy Metal Sensing

VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...

Published: 10/9/2025 | Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Tumi Olason, Mohammad Kafi Kangi

Keywords(s):

Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement

Pipeline Inspection Robot

VALUE PROPOSITION Pipelines represent a major supporting industry for utilities and are used in a variety of applications such as for natural gas, water, and oil, as well as residential distribution. Natural gas pipelines alone travel over 2.5 million miles, delivering 28.3 trillion cubic feet of natural gas to customers in the United States alone....

Published: 3/21/2025 | Inventor(s): Xiaobo Tan, Preston Fairchild, Claudia Chen, Yiming Deng, Mohand Alzuhiri, Zi Li, Xinda Qi

Keywords(s):

Category(s): Environmental, Test and Measurement

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 9/12/2025 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

Keywords(s):

Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Implantable Neural Microelectrodes and Fabrication Method

Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...

Published: 2/17/2023 | Inventor(s): Wen Li, Yue Guo, Thomas Schuelke, Michael Becker, Robert Rechenberg, Cory Rusinek

Keywords(s):

Category(s): Advanced Materials, Biotechnology, Devices

Flexible Hybrid Diamond Biosensor

Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...

Published: 6/8/2021 | Inventor(s): Wen Li, Bin Fan, Michael Becker, Robert Rechenberg

Keywords(s):

Category(s): Advanced Materials, Devices

Wireless Intraocular Pressure Sensor to Monitor Glaucoma Patients

Executive SummaryGlaucoma is a leading cause of blindness that affects up to 3 million people in American. It can remain undetected until permanent vision loss is present. Measuring eye pressure during an office visit is a standard diagnostic tool. However, this measurement can only report on pressure during a brief time sample. Patients with variable...

Published: 6/15/2023 | Inventor(s): Wen Li, Arthur Weber, Mohammad Hossein Kouhani

Keywords(s):

Category(s): Medical, Biotechnology, Test and Measurement

Transparent Electrode Array for Optogenetics

Executive SummaryThe development of brain-machine interface technologies offer a host of opportunities for basic research, real-time therapeutic devices, and neural prosthetics. Our bi-directional communication channel provides for a more robust brain-machine interface with greater accuracy. The bi-directional communication channel is also critical...

Published: 4/24/2025 | Inventor(s): Wen Li, Ki Yong Kwon

Keywords(s):

Category(s): Medical, Biotechnology, Devices

Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers

Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources

1 2