Search Results - ziwen+li

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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025   |   Inventor(s): Li Li, Shichao Wu, Jiawei Zhao
Keywords(s):  
Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic
Low-Cost High-Performance 3D LiDAR Imaging System
Description: This innovative 3D imaging system uses time-of-flight measurement of photons with a conventional global shutter CMOS camera to generate accurate distance data converted into brightness levels. It includes a laser source, camera, delay generator, master trigger, and electronic control unit (ECU) which together capture and average multiple...
Published: 12/16/2025   |   Inventor(s): Wen Li, Suk Kyoung Lee, Blessed Oguh, Sulaiman Abubakar
Keywords(s):  
Category(s): Technology Category > Automotive & Transportation, Technology Category > Physical Sciences, Technology Category > Image Analysis (Cameras & Software), Technology Category > Revolutionizing Mobility
Interactive Systems and Methods for Identifying Target Proteins in Drug Discovery (Case No. 2025-098)
Summary: UCLA researchers from the Department of Electrical and Computer Engineering have developed a novel computational system for target protein identification, enabling integrative drug discovery. Background: Target identification (Target ID) in drug discovery involves the identification and evaluation of protein candidates that could interact...
Published: 10/1/2025   |   Inventor(s): Xiang Chen, Youngseung Jeon, Christopher Hwang, Ziwen Li, Jesus Campagna, Varghese John, Whitaker Cohn, Eunice Jun
Keywords(s): AI-driven drug discovery, Alzheimer’s disease target discovery, Bioinformatics software platform, Drug, Drug Discovery, Functional annotation of proteins, High-throughput docking, large language models (LLMs), Ligand-protein docking, Mechanism-of-action prediction, Molecular docking simulation, Multi-criteria decision support, Neurodegenerative disease therapeutics, Pathway-centric drug targeting, personalized medicine, PPI-Comparator, PPI-Explorer, Protein structure prediction, Protein-protein interaction (PPI) analysis, Rational drug design, Retrieval-augmented generation (RAG), Semantic similarity modeling, Small molecule screening, Systems biology interface, Target identification (Target ID), Therapeutic impact modeling, User-guided AI exploration
Category(s): Software & Algorithms, Software & Algorithms > AI Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Digital Health, Life Science Research Tools, Life Science Research Tools > Research Methods, Platforms, Platforms > Drug Delivery
Bioplatform to Identify and Characterize Pathogens and Therapies against Tuberculosis and Other Granulomatous Diseases.
Treatment for human tuberculosis (TB) and other granulomatous diseases would benefit from high- throughput screening (HTS)-compatible platform replicating physiological conditions in hallmark granuloma lesions. However, currently available screening platforms and 2-D and 3-D cell culture systems lack throughput and key features, and relevant microenvironments...
Published: 5/9/2025   |   Inventor(s): Suraj Sable, James Posey, Wen Li, Allison Kline
Keywords(s):  
Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Infectious Disease, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Heavy Metal Sensing
VALUE PROPOSITION Heavy metal pollution in soils is widespread in the world, resulting from both natural sources and human activities (e.g., mining and smelting, industrial emission, fossil fuel combustion, etc.). Due to their toxicity, bioaccumulation, and environmental persistence, elevated levels of heavy metals in the environment pose major threats...
Published: 10/21/2025   |   Inventor(s): Wen Li, Hasan Banna, James Siegenthaler, Mohammad Kafi Kangi, Tumi Olason
Keywords(s):  
Category(s): Agriculture, Analytical Instruments, Environment, Test and Measurement
Pipeline Inspection Robot
VALUE PROPOSITION Pipelines represent a major supporting industry for utilities and are used in a variety of applications such as for natural gas, water, and oil, as well as residential distribution. Natural gas pipelines alone travel over 2.5 million miles, delivering 28.3 trillion cubic feet of natural gas to customers in the United States alone....
Published: 3/21/2025   |   Inventor(s): Xiaobo Tan, Preston Fairchild, Claudia Chen, Yiming Deng, Mohand Alzuhiri, Zi Li, Xinda Qi
Keywords(s):  
Category(s): Environmental, Test and Measurement
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Implantable Neural Microelectrodes and Fabrication Method
Executive SummaryMicroelectrodes have become vital in the current-day attempt to map and understand the human brain, as well as delivering unique therapeutic solutions. These microelectrodes are able to work as biosensors, picking up changes in potential and electrophysiology. In particular, extracellular sensors can record data on neurotransmitter...
Published: 2/17/2023   |   Inventor(s): Wen Li, Yue Guo, Thomas Schuelke, Michael Becker, Robert Rechenberg, Cory Rusinek
Keywords(s):  
Category(s): Advanced Materials, Biotechnology, Devices
Flexible Hybrid Diamond Biosensor
Executive SummaryA unique fabrication method creates a new flexible and implantable thin film sensor for the biochemical, medical and neural engineering fields. This diamond-polymer hybrid demonstrates improved biocompatibility, durability and chemical sensing capabilities. Description of TechnologyThe rigidness and attachment incompatibilities of...
Published: 6/8/2021   |   Inventor(s): Wen Li, Bin Fan, Michael Becker, Robert Rechenberg
Keywords(s):  
Category(s): Advanced Materials, Devices
Wireless Intraocular Pressure Sensor to Monitor Glaucoma Patients
Executive SummaryGlaucoma is a leading cause of blindness that affects up to 3 million people in American. It can remain undetected until permanent vision loss is present. Measuring eye pressure during an office visit is a standard diagnostic tool. However, this measurement can only report on pressure during a brief time sample. Patients with variable...
Published: 6/15/2023   |   Inventor(s): Wen Li, Arthur Weber, Mohammad Hossein Kouhani
Keywords(s):  
Category(s): Medical, Biotechnology, Test and Measurement
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