Search Results - yucheng+zhang

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3D-printed biosensors for high-sensitivity molecular detection

This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...

Published: 7/26/2024 | Inventor(s): Mohammed Maniruzzaman, Yu Zhang

Keywords(s):

Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic

“Bio-Flex”: advanced formulation for sustainable stereolithography (SLA)

Background/problem Stereolithography (SLA) 3D printing has transformed the biomedical field with creation of highly accurate, patient-specific medical devices such as tissue scaffolds, implants, and surgical tools. This technology leverages computer-aided design and medical imaging data to produce structures with precise geometries at submicron scales....

Published: 7/26/2024 | Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Anqi Lu

Keywords(s):

Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Therapeutics > Drug delivery

Novel Small Molecule Inhibitors Targeting Clostridioides Difficile Sporulation

Advantages: The development of DBO compounds represents a novel therapeutic approach to tackling CDI. By inhibiting C. difficile sporulation, DBO compounds address a major cause of CDI recurrence, reducing the likelihood of patients experiencing repeated infections. DBO compounds improve the effectiveness of existing antibiotics used to treat...

Published: 10/2/2023 | Inventor(s): Yu Chen, Michael Sacco, James Leahy, Elena Bray, Xingmin Sun, Xiujun Zhang

Keywords(s): Drug Discovery, Infectious Diseases Treatment

Category(s): Technology Classifications > Medical > Therapeutics, Technology Classifications > Medical > Pharmaceuticals, Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Infectious Diseases, Technology Classifications > Medical > Biotechnology

Thermal Control During Additive Manufacturing

THE CHALLENGE Additive manufacturing (AM) has emerged as a powerful tool within engineering. Many AM and coating processes rely on thermal input to soften or melt the materials involved in processing. However, this melting or softening typically results in a higher thermal gradient between deposited material and the workpiece, commonly resulting in...

Published: 12/20/2023 | Inventor(s): Robert Griffiths, David Garcia, Hang Yu

Keywords(s):

Category(s): EXPERIMENT--DO NOT USE, Technology Classifications > Additive Manufacturing

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING

ONE GRAM PENNY-SIZED WIRELESS EEG RECORDING PATCH FOR LONG-TERM MENTAL HEALTH MONITORING Researchers at Stanford have developed a wearable patch that allows for continuous mental health monitoring via electroencephalogram (EEG) recording. EEG technology was developed during the advent of neuroscience nearly a century and a half ago. EEG technology...

Published: 8/17/2023 | Inventor(s): Ada Poon, Cheng Chen, Joonseok Yang, Hui Wang

Keywords(s): EEG, Neurology, Wearable

Category(s): Technology Classifications > Engineering

FIBP Knockout Potentiates Therapeutic Effects of T-cell Based Therapies in Solid Tumors

Abstract: Despite recent breakthroughs in cancer immunotherapy, T-cell based therapies achieve limited efficacy in solid tumors. Immunosuppression, antigen escape and physical barriers to entry into solid tumors are issues faced. Identifying regulators in T-cell dysfunction remains challenging due to limitations of current screening platforms. Using...

Published: 4/8/2024 | Inventor(s): Peng Jiang, Yu Zhang

Keywords(s): adoptive cell therapy, Cancer Immunotherapy, cholesterol metabolism, Computational Model, FGF1 Intracellular Binding Protein, FIBP, Jiang, solid tumors, T-Cell based Therapy, T-Cell Resilience

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics

Automated Flight Planning System for Urban Air Mobility

Advantages: AFPS uses advanced algorithms for airspace management and conflict resolution, ensuring safety in high-density Urban air mobility (UAM) environments. AFPS enhances UAM efficiency by optimizing airspace use and generating conflict-free flight paths. AFPS allows Providers of Service for UAM (PSU) to provide seamless airspace and traffic...

Published: 9/3/2024 | Inventor(s): Yu Zhang

Keywords(s): Industrial Applications, Transportation

Category(s): Technology Classifications > Engineering > Drones, Technology Classifications > Engineering > Mechanical Engineering, Technology Classifications > Engineering > Sensors, Technology Classifications > Energy & Environment

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Routes Optimization System Based on Railroad and Street Traffic Information

Reference #: 01565 The University of South Carolina is offering licensing opportunities for Routes Optimization System Based on Railroad and Street Traffic Information Background: Current navigation systems, such as Google Maps, Apple Maps, calculates the optimal route based on the street traffic information. But still, the travelers would need to...

Published: 1/31/2023 | Inventor(s): Yu Qian, Yuche Chen

Keywords(s): delay, dynamic programming, optimal route selection, Railroad crossing blockage, street traffic

Category(s): Software and Computing, Engineering and Physical Sciences

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 3/15/2023 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

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