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Quamba2: a robust and scalable post-training quantization framework for selective state space models (SSMs)
Quamba2 highlights Supports W4A8 / W4A16 / W4AX / W8A8 for Mamba1 and Mamba2 Achieves 4x memory reduction and 3x generation speedup Enables 8B model inference on Orin Nano 8G at 13 tokens/sec Outperforms W4A8KV4 Llama3-8B in both speed and quality Background Deploying state space models (SSMs), which excel at processing long sequences but demand...
Published: 4/9/2025   |   Inventor(s): Diana Marculescu, Hung-Yueh Chiang, Chi-Chih Chang, Natalia Frumkin, Mohamed Abdelfattah, Kai-Chiang Wu
Keywords(s):  
Category(s): Software > AI, Computer > AI/ML > Language processing
Use of 2-Hydroxyoleic Acid for the Treatment of Systemic Lupus Erythematosus and Other Immune Pathologies
A novel B cell tolerance pathway activated by the lipid enzyme sphingomyelin synthases 2 (SMS2). Background: Autoimmune diseases such as Systemic Lupus Erythematosus are chronic, painful and debilitating. The Lupus Foundation of America estimates that 1.5 million Americans, and at least five million people worldwide, have some form of lupus. The...
Published: 4/1/2025   |   Inventor(s): Chongmin Huan, Christopher Roman, Peiqi Ou
Keywords(s): TAF, Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Therapeutics and Vaccines
DNAzyme fluorescent sensors for bioselective imaging of Fe²⁺ and Fe³⁺ ions
Developed DNAzyme-based fluorescent sensors that specifically detect and image Fe2⁺ and Fe3⁺ ions in living cells, enabling the study of iron dynamics in biological processes and diseases like Alzheimer’s. Background Iron ions, specifically Fe2⁺ and Fe3⁺, are essential for numerous biological processes, including oxygen transport, DNA synthesis,...
Published: 1/31/2025   |   Inventor(s): Yi Lu, Seyed-Fakhreddin Torabi, Yuting Wu, Ryan Lake, Zhenglin Yang, Peiwen Wu, Whitney Lewis, Jacqueline Van Stappen, Xiangli Shao
Keywords(s):  
Category(s): Life sciences > Biomaterials
DNAzyme fluorescent sensors for bioselective imaging of Fe²⁺ and Fe³⁺ ions
Developed DNAzyme-based fluorescent sensors that specifically detect and image Fe2⁺ and Fe3⁺ ions in living cells, enabling the study of iron dynamics in biological processes and diseases like Alzheimer’s. Background Iron ions, specifically Fe2⁺ and Fe3⁺, are essential for numerous biological processes, including oxygen transport, DNA synthesis,...
Published: 1/31/2025   |   Inventor(s): Yi Lu, Seyed-Fakhreddin Torabi, Yuting Wu, Ryan Lake, Zhenglin Yang, Peiwen Wu, Whitney Lewis, Jacqueline Van Stappen, Xiangli Shao
Keywords(s):  
Category(s): Life sciences > Biomaterials
Quamba: Post-training quantization for selective state space models
Background State Space Models (SSMs) are integral to numerous advanced technologies, including natural language processing, robotics, autonomous vehicles, and edge computing systems. As these applications increasingly demand real-time processing and intelligent decision-making on devices with limited computa­tional resources, there is a pressing...
Published: 1/23/2025   |   Inventor(s): Diana Marculescu, Hung-Yueh Chiang, Chi-Chih Chang, Natalia Frumkin, Kai-Chiang Wu
Keywords(s):  
Category(s): Computer > AI/ML, Computer > AI/ML > Language processing, Software > AI > Machine learning
Cancer treatment through hTERT inhibition
Title: Cancer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025   |   Inventor(s): Laurence Hurley, Vijay Gokhale, HyunJin Kang, Kui Wu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology
A Self-Regenerative Heat Pump (Case No. 2025-042)
Summary: UCLA researchers from the Department of Materials Science and Engineering have developed an innovative device designed to optimize heat transport with improved efficiency and flexibility. Background: Heat transfer technologies play a crucial role in a wide range of applications, from thermoelectric coolers to vapor-compression systems, enabling...
Published: 2/14/2025   |   Inventor(s): Qibing Pei, Hanxiang Wu, Yuan Zhu, Wenzhong Yan, Sumanjeet Kaur
Keywords(s): Flexible Electronics, heat control, heat controlling devices, Heat Transfer, joule heating, light-to-heat conversion, Virtual Reality Braille Haptic Technology Joule Heating
Category(s): Materials, Materials > Functional Materials, Electrical, Electrical > Flexible Electronics, Medical Devices, Mechanical, Mechanical > Heat Transfer
Methods of Detecting Loss of Heterozygosity and Damaging Mutations in Immune-Related Genes Using Liquid Biopsies
Summary: The National Cancer Institute (NCI) seeks co-development partners and/or licensees for a liquid biopsy diagnostic assay capable of detecting loss of heterozygosity (LOH) and somatic mutations in genes important for antigen processing and presentation and interferon-γ response pathways. Description of Technology: Immunotherapy is...
Published: 12/9/2024   |   Inventor(s): Scott Norberg, Andrew Sinkoe, Xiaolin Wu, James Gulley
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Immunology
NetSpec: An Automatic And Fast Network Specification Synthesis Toolkit
A specification-by-example toolkit that generates formal network specifications using only input-output examples. Problem: Many modern computer systems run on networks like cloud clusters or distributed systems. However, the network protocols that support the operation and security of these systems are notoriously difficult to debug. Formal network...
Published: 11/19/2024   |   Inventor(s): Boon Loo, Haoxian Chen, Mayur Naik, Chenyuan Wu, Mukund Raghothaman
Keywords(s): Software
Category(s): Technology Classifications > Computer Information Systems
Crowd-Sourced Traffic Speed Module
The Crowd-Sourced Traffic Speed Module is one of the many fundamental components of high-performance statewide transportation analytics and visualizations tools. This new tool, using crowdsourced vehicle speed data, allows agencies and organizations to make informed decisions with comprehensive vehicle data on a state-wide level for a safer, more efficient...
Published: 3/13/2025   |   Inventor(s): Yao-Jan Wu, Gabriel Geffen, Pei-Yu Leu
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Transportation & Automotive, Technology Classifications > Software & Information Technology > Transportation
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