Search Results - you+wu

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Cancer treatment through hTERT inhibition
Title: Cancer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025   |   Inventor(s): Laurence Hurley, Vijay Gokhale, HyunJin Kang, Kui Wu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology
A Self-Regenerative Heat Pump (Case No. 2025-042)
Summary: UCLA researchers from the Department of Materials Science and Engineering have developed an innovative device designed to optimize heat transport with improved efficiency and flexibility. Background: Heat transfer technologies play a crucial role in a wide range of applications, from thermoelectric coolers to vapor-compression systems, enabling...
Published: 1/3/2025   |   Inventor(s): Qibing Pei, Hanxiang Wu, Yuan Zhu, Wenzhong Yan, Sumanjeet Kaur
Keywords(s): Flexible Electronics, heat control, heat controlling devices, Heat Transfer, joule heating, light-to-heat conversion, Virtual Reality Braille Haptic Technology Joule Heating
Category(s): Materials, Materials > Functional Materials, Electrical, Electrical > Flexible Electronics, Medical Devices, Mechanical, Mechanical > Heat Transfer
Methods of Detecting Loss of Heterozygosity and Damaging Mutations in Immune-Related Genes Using Liquid Biopsies
Summary: The National Cancer Institute (NCI) seeks co-development partners and/or licensees for a liquid biopsy diagnostic assay capable of detecting loss of heterozygosity (LOH) and somatic mutations in genes important for antigen processing and presentation and interferon-γ response pathways. Description of Technology: Immunotherapy is...
Published: 12/9/2024   |   Inventor(s): Scott Norberg, Andrew Sinkoe, Xiaolin Wu, James Gulley
Keywords(s):  
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Oncology, TherapeuticArea > Immunology
NetSpec: An Automatic And Fast Network Specification Synthesis Toolkit
A specification-by-example toolkit that generates formal network specifications using only input-output examples. Problem: Many modern computer systems run on networks like cloud clusters or distributed systems. However, the network protocols that support the operation and security of these systems are notoriously difficult to debug. Formal network...
Published: 11/19/2024   |   Inventor(s): Boon Loo, Haoxian Chen, Mayur Naik, Chenyuan Wu, Mukund Raghothaman
Keywords(s): Software
Category(s): Technology Classifications > Computer Information Systems
Crowd-Sourced Traffic Speed Module
The Crowd-Sourced Traffic Speed Module is one of the many fundamental components of high-performance statewide transportation analytics and visualizations tools. This new tool, using crowdsourced vehicle speed data, allows agencies and organizations to make informed decisions with comprehensive vehicle data on a state-wide level for a safer, more efficient...
Published: 10/21/2024   |   Inventor(s): Yao-Jan Wu, Gabriel Geffen, Pei-Yu Leu
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Transportation & Automotive, Technology Classifications > Software & Information Technology > Transportation
Predicting breast cancer response to therapy with MRI and modeling
Background/problem Neoadjuvant therapy (NAT) for cancer treatment is currently based on generalized population-based data such as receptor status, tumor grade, body surface area, and genetic markers. This approach is inherently limited, as it does not account for the unique spatial and physiological characteristics of individual tumors. Consequently,...
Published: 11/5/2024   |   Inventor(s): Thomas Yankeelov, Angela Jarrett, David Hormuth, Anum Kazerouni, Chengyue Wu, Stephanie Barnes
Keywords(s):  
Category(s): Life sciences > Imaging, Life sciences > Diagnostic
Liquid Metal Printing Technique via Optical Maskless Lithography (Case No. 2024-031)
Summary: Researchers in the UCLA Department of Materials Science and Engineering have developed a facile, rapid method to print soft, wearable electronics. Background: Soft electrical circuits have garnered significant interest in a broad range of emerging technologies, including wearable electronics, brain-machine interfaces, and soft robotics....
Published: 10/15/2024   |   Inventor(s): Ximin He, Dong Wu
Keywords(s): Coating, Coatings, Adhesives, & Inks, Electronics & Semiconductors, Fabrication Technologies, gallium-based liquid metals, General Device Coatings, Liquid metal particles, liquid metals, Metals, Microelectronics Semiconductor Device Fabrication, Polymer, Polymers, scalable fabrication, Semiconductor Device Fabrication, soft electrical circuits, soft electronics, wearable electronics, wearable sensors
Category(s): Chemical, Chemical > Polymers, Chemical > Coatings, Adhesives & Inks, Electrical, Electrical > Electronics & Semiconductors, Electrical > Sensors, Electrical > Instrumentation, Electrical > Flexible Electronics, Materials, Materials > Fabrication Technologies, Materials > Composite Materials, Materials > Metals
Small molecule inhibitor of ARID4B to combat endocrine therapy resistance in breast cancer
Large-scale genomic analyses, including data from The Cancer Genome Atlas (TCGA) and other breast cancer datasets, have identified amplification of the AT-rich interactive domain 4B (ARID4B) protein, also known as retinoblastoma binding protein 1-like 1 (RBP1L1), in approximately 22% of human breast cancer cases. Compelling clinical evidence highlights...
Published: 8/20/2024   |   Inventor(s): Samuel Awuah, Mei-Yi Wu, Ray-Chang Wu, Samuel Ofori
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Therapeutics
Small molecule inhibitor of ARID4B to combat endocrine therapy resistance in breast cancer
Large-scale genomic analyses, including data from The Cancer Genome Atlas (TCGA) and other breast cancer datasets, have identified amplification of the AT-rich interactive domain 4B (ARID4B) protein, also known as retinoblastoma binding protein 1-like 1 (RBP1L1), in approximately 22% of human breast cancer cases. Compelling clinical evidence highlights...
Published: 8/20/2024   |   Inventor(s): Samuel Awuah, Mei-Yi Wu, Ray-Chang Wu, Samuel Ofori
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Therapeutics
Improved Methods For Cryopreservation Of Cells, Tissues, And Organs
Summary: The National Eye Institute seeks research co-development partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...
Published: 12/23/2024   |   Inventor(s): Jingxing Ou, Kiyoharu Miyagishima, Guanghui Jin, Wei Li, Lihao Ge
Keywords(s):  
Category(s): Application, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, Collaboration Sought > Licensing
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