Search Results - xiaoming+liu

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BASH-GN: A New Machine Learning–Derived Questionnaire for Screening Obstructive Sleep Apnea
BASH-GN is a machine learning-based questionnaire designed to classify the risk of obstructive sleep apnea (OSA) by considering various risk factor subtypes. Compared with other commonly used OSA screening tools, the BASH-GN questionnaire demonstrated superior performance, making it a more effective option for identifying at-risk individuals. This questionnaire...
Published: 9/23/2024   |   Inventor(s): Ao Li, Jiayan Huo, Stuart Quan, Janet Roveda
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Sleep Disorders
A Transformer-Based Diffusion Probabilistic Model for Vital Signs Forecasting
The model proposed in this technology, Transformer-based Diffusion Probabilistic Model for Sparse Time Series Forecasting (TDSTF), is a novel deep-learning algorithm that can be used for vital signs forecasting, data synthesis, simulation, and digital twins. Trained and tested on data from over 46,000 patients, the TDSTF technology merges transformer...
Published: 8/23/2024   |   Inventor(s): Ao Li, Ping Chang, Huayu Li, Janet Roveda
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Software & Information Technology > Web & Internet
MTS-LOF: Medical Time-Series Representation Learning via Occlusion-Invariant Features
Medical Time Series Representation Learning, known as MTS-LOF, uses the strengths of contrastive learning and Masked Autoencoder (MAE) methods, providing more sophisticated, context-rich representations, while also clarifying the interplay between temporal and structural dependencies in healthcare data. MTS-LOF is ideal for integration into numerous...
Published: 8/23/2024   |   Inventor(s): Ao Li, Huayu Li, Ana Carreon-Rascon
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Web & Internet, Technology Classifications > Software & Information Technology > Health IT
DeScoD-ECG: Deep Score-Based Diffusion Model for ECG Baseline Wander and Noise Removal
The DeScoD-ECG model is a novel electrocardiogram (ECG) baseline wander and noise removal technology that extends the current diffusion model for reconstructing electrocardiogram signals. It establishes a new benchmark in biomedical signal processing to provide a more accurate approximation of ECG signals for detection of cardiovascular irregularities....
Published: 8/23/2024   |   Inventor(s): Ao Li, Huayu Li, Gregory Ditzler, Janet Roveda
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Communications & Networking, Technology Classifications > Software & Information Technology > Open Source, Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Diagnostics
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 6/5/2024   |   Inventor(s): Li Liu, Jingmin Shu
Keywords(s):  
Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices
Telomere assay for the detection of alternative lengthening of telomere (ALT) activity in cells
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A unique tool for distinguishing cancer cells based on telomere maintenance mechanisms, providing potential biomarkers for cancer subtypes and therapeutic responses. Description: This technology provides detailed telomere profiling from individual chromosomes, capable of differentiating...
Published: 6/28/2024   |   Inventor(s): Ming Xiao
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Quantification of On-off target gene editing by optical mapping
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A revolutionary methodology for quantifying on-target and off-target gene editing activity using CRISPR-Cas9 and optical mapping. Description: This technology comprises a single-molecule optical mapping strategy using CRISPR-Cas9 to fluorescently label the modified genes. The method involves...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Yilin Wang, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Research Tools & Materials, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering
Multicolor whole-genome mapping for genetic analysis
PAGE TITLE Overview PAGE SUMMARY Executive Statement: A novel method for precise genome mapping and sequencing using Cas9-mediated labeling within nanochannels. Description: This technology is a method for mapping a whole genome using a universal multi-color mapping strategy in nanochannels that combines a conventional sequence-motif labeling...
Published: 6/20/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Research Tools & Materials
Linked-read sequencing library preparation
PAGE TITLE Overview PAGE SUMMARY Executive Statement: Innovative methods for generating sequence-linked DNA fragments for high-quality, low-cost genome sequencing. Description: This technology describes a novel strategy to construct a long-read sequencing library such that adjacent fragments are linked with end-terminal duplications. The...
Published: 6/28/2024   |   Inventor(s): Ming Xiao, Lahari Uppuluri
Keywords(s):  
Category(s): Life Sciences, Medical Devices & Diagnostics > MDD: Diagnostic Tests, Pharmaceuticals & Therapeutics > Pharma: Genome Engineering, Pharmaceuticals & Therapeutics > Pharma: Gene Therapy, Pharmaceuticals & Therapeutics > Pharma: Cellular Therapy, Research Tools & Materials
Deep Learning Algorithm for Detection of Cortical Arousal During Sleep
This invention is an end-to-end deep learning algorithm to detect cortical arousals during sleep using a one-night single lead electrocardiogram (ECG) signal. It is used to accurately detect arousal in home sleep tests, by reducing the false negative rate. The model combines both convolutional neural networks (CNN) and recurrent neural networks (RNN). Background: Sleep...
Published: 10/8/2024   |   Inventor(s): Ao Li, Siteng Chen, Stuart Quan, Linda Powers, Janet Roveda
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Sleep Disorders, Technology Classifications > Software & Information Technology > Health IT
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