Search Results - xiaodi+yao

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Endothelium-Specific Laminin Reporter Mouse Line Laminin-mCherry/eGFP+/–; Cdh5-CreER+/– Mouse Line
Advantages Enables endothelial-specific labeling of laminin-γ1 in vivo. Tamoxifen-inducible system allows temporal control of recombination. Dual-color fluorescence distinguishes target cell-derived laminin from other cell-derived laminin. Co-localization with laminin-γ1 antibody confirms biological fidelity. Facilitates mapping...
Published: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
MicroRNAs (miRNAs) for the Treatment of Neurological Disorders
Application Oligonucleotides that target Kv4.2 miRNAs for the upregulation of Kv4.2 protein in neurological disorders. Key Benefits Increases the abundance of the neuro-protective protein, Kv4.2. Offers a potential treatment for neurological diseases, including Fragile X syndrome, autism spectrum disorders, epilepsy, and Alzheimer's disease. Market...
Published: 10/3/2025   |   Inventor(s): Gary Bassell, Xiaodi Yao, Christina Gross
Keywords(s): Cell Therapy, Neurology and Pain Treatments
Category(s): TechPub Algolia > Drug Discovery