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Search Results - xiangsheng+liu
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IRF4-Engineered T Cells Induce T Cell Function As a Treatment Strategy for Solid Tumors
Asset/Technology Type New Therapeutic Strategy Description of Invention The invention includes compositions and methods of delivering therapeutic anti-tumor T cells by forcing them to overexpress interferon regulatory factor (IRF4) as a treatment for various solid tumors, including but not limited to melanoma, lymphoma, and colon cancer. The inventors...
Published: 4/11/2025
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Inventor(s):
Wenhao Chen
,
Xian Li
Keywords(s):
Category(s):
Clinical Area > Transplantation
,
Clinical Area > Cancer
,
Clinical Area > Metabolic Disease, Inflammation, and Immunology
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Research Area > Cancer
,
Research Area > Immunobiology and Inflammation
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Technology Classifications > Therapeutic > Cell and Gene Therapies
Novel Helical Peptodomimetics that Prevent the Formation of Aβ Oligomerization in Alzheimer’s Disease (AD)
Advantages: Developed sulfonyl-γ-AA peptide helical peptidomimetics that can prevent the formation of neurotoxic Aβ oligomerization. High Specificity: The lead sulfonyl-γ-AApeptide helical foldamer, Ab-6, exhibits precise targeting to the central region of Aβ42 and induces α-helix conformation in Aβ. Sequence-Specific...
Published: 2/19/2025
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Inventor(s):
Jianfeng Cai
,
Heng Liu
Keywords(s):
Alzheimer's Disease
,
Biotechnology
,
Neurodegenerative Diseases
Category(s):
Technology Classifications > Medical > Biomedical Engineering
,
Technology Classifications > Medical > Biotechnology
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Technology Classifications > Medical > Neuroscience
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 2/13/2025
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Inventor(s):
Li Liu
,
Jingmin Shu
Keywords(s):
Category(s):
Applied Technologies
,
Genomic Assays/Reagents/Tools
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Life Science (All LS Techs)
,
Diagnostic Assays/Devices
Automated Failure Prediction System for Transportation Infrastructure
se; } Automated Infrastructure: Integration of Diverse Data Invention Summary: The degradation monitoring of transportation infrastructure such as roads and railways, in the US faces challenges due to the vastness of the network and limited resources for continuous inspection. There is a need for predictive maintenance and life-cycle management...
Published: 1/29/2025
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Inventor(s):
Xiang Liu
Keywords(s):
Data Science
Category(s):
Technology Classifications > Software & Copyright
,
Technology Classifications > Software & Algorithms
2022-116-1 Electrolyte Modulator Additive for Lithium-Ion Batteries
Summary: UCLA researchers in the Department of Chemical and Biomolecular Engineering have designed a MOF-based electrolyte modulator to mitigate the polarization of electrolytes in lithium-ion batteries for energy efficient electric vehicles. Background: To ensure a successful transition to electric vehicles, it is essential to develop low-cost...
Published: 2/14/2025
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Inventor(s):
Yunfeng Lu
,
Li Shen
,
Xinru Li
Keywords(s):
Charge Carrier
,
Electric Vehicle
,
Energy Density
,
Energy Efficiency
,
Hybrid Electric Vehicle
,
Lithium Battery
,
Lithium-Ion Battery
,
Metal-Organic Framework
,
Polarizer
,
Rechargeable Battery
,
Rechargeable Battery Thermal Conductivity
Category(s):
Electrical
,
Energy & Environment > Energy Storage
,
Energy & Environment > Energy Storage > Batteries
Intelligent Multi-Beam Medium Access Control in Ku-Band for Mission-Oriented Mobile Mesh Networks
The Problem: There are existing similar technologies, but these technologies are not designed for mobile mission-oriented applications. The use of Ku-band frequency on two separate information transmission levels reduces interference common with current multi-beam antennas. Also, the Ku-band frequency is not the currently used frequency range...
Published: 2/27/2023
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Inventor(s):
Fei Hu
,
xI Li
,
Sunil Kumar
Keywords(s):
Category(s):
Technology Classifications > Communication
Improving the Efficacy of Immunotherapy
Improving the Efficacy of Immunotherapyhttps://sites.google.com/slu.edu/intellectualproperty/2022/22-026
Published: 8/18/2023
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Inventor(s):
Guangyong Peng
,
Xia Liu
Keywords(s):
Category(s):
Therapeutics
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 2/18/2025
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
JobViz: User Interface for Visualization of Majors & Jobs
Invention Summary: University (and industry) career search portals and web-based job search engines allow users to search on many items (e.g., education, location, level, etc.) and then present a text based list of potential job opportunities. University career portals are not as conductive to exploration by job and career searchers as they could...
Published: 9/8/2022
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Inventor(s):
Deborah Silver
,
Li Liu
Keywords(s):
Category(s):
Technology Classifications > Software & Copyright
,
Technology Classifications > Software & Algorithms
Improving Tumor Immunotherapy
Improving Tumor Immunotherapy
Published: 6/14/2021
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Inventor(s):
Guangyong Peng
,
Xia Liu
Keywords(s):
Category(s):
Therapeutics
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