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Search Results - william+lowry
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Development of Novel Compounds to Suppress Neuronal Stress and Cross the Blood Brain Barrier (UCLA Case No. 2021-165)
SUMMARY: An interdisciplinary group of UCLA researchers have developed and validated a library of compounds that alleviate symptoms of Rett Syndrome and hold enormous therapeutic potential for the long-term treatment of other intellectual disability syndromes. BACKGROUND: Intellectual disability (ID) affects more than 100 million people globally and...
Published: 5/8/2024
|
Inventor(s):
William Lowry
,
Michael Jung
,
Xiaoguang Liu
,
Elena Korsakova
Keywords(s):
blood-brain barrier
,
Drug
,
intellectual disability
,
Organoids
,
senescence
Category(s):
Therapeutics > CNS and Neurology
,
Life Science Research Tools
,
Diagnostic Markers > Targets And Assays
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
2020-777: Correcting Neuronal Dysfunction in Intellectual Disability Syndromes
UCLA researchers in the department of Molecular, Cellular, and Developmental Biology have developed a treatment that could mitigate some mental issues related to various intellectual disabilities syndromes. BACKGROUND: Approximately 6.5 million people in the United states have an intellectual disability syndrome, classified as an IQ of less than 70....
Published: 9/20/2023
|
Inventor(s):
William Lowry
Keywords(s):
Cns
,
Genetic Disease
,
Therapeutics & Vaccines
Category(s):
Therapeutics
,
Therapeutics > CNS and Neurology
2019-720: Preventing Senescence to Improve Neuronal Function in Intellectual Disability Disorders
UCLA researchers in the Department of Molecular and Cell & Developmental Biology have developed novel therapeutic strategy to treat intellectual disability disorders discovered via a screening platform for drug discovery in a human model of brain development. BACKGROUND: Rett syndrome is an X-linked genetic neurological disease associated...
Published: 9/20/2023
|
Inventor(s):
William Lowry
Keywords(s):
Cns
,
Genetic Disease
,
Therapeutics & Vaccines
Category(s):
Therapeutics > CNS and Neurology
Inhibition of Pyruvate Oxidation to Promote Hair Growth
Case 2018-189UCLA researchers in the departments of Molecular, Cell & Developmental Biology and Biological Chemistry have elucidated a novel mechanism by which pyruvate oxidation can be inhibited in order to promote hair growth.BACKGROUNDThe global market for aging-related hair loss will grow to over $1.4 billion by 2020. However, commercially available...
Published: 7/19/2023
|
Inventor(s):
William Lowry
,
Heather Christofk
Keywords(s):
Category(s):
Therapeutics > Metabolism And Endocrinology
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
,
Jacques Albert
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Fiber Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources