Search Results - wei+(helena)+he

290 Results Sort By:
Small-Molecule IL-6 Inhibitors Targeting gp130 for Anti-Cancer Therapy
Blocks IL-6-gp130 Signaling for Cost-Effective Treatment of Autoimmune Diseases and IL-6–Driven Cancers These small-molecule interleukin-6 (IL-6) inhibitors target glycoprotein 130 (gp130) by blocking IL-6-gp130 signaling, delivering a cost-effective therapy for autoimmune diseases and IL-6-driven cancers. IL-6-gp130 signaling drives tumor growth...
Published: 3/2/2026   |   Inventor(s): Chenglong Li, Liguang Mao, Daniel Schultz, Zhihang Shen, Xiaozhi Yang, Wei Zhou
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Compositions and Methods to Modulate MAVS-Mediated Immunity (UCLA Case No. 2026-096)
UCLA researchers in the Department of Microbiology, Immunology, and Molecular Genetics have developed methods to target TOM70, a mitochondrial outer membrane protein, to selectively modulate innate immune signaling and control pathological or protective immune responses across a range of clinical conditions. BACKGROUND: Innate immune detection of viral...
Published: 2/18/2026   |   Inventor(s): Lena Pernas
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology, Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Autoimmune, Therapeutics > Vaccines
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Ultrasonic Process for Selective Extraction of Lithium and Magnesium From Suitable Geological Precursors and Alkaline Indust (Case No. 2022-135)
Summary UCLA researchers have developed new methods for designing and synthesizing inorganic porous materials and extracting valuable metal ions from natural and waste sources. The first technology uses metal cations as inorganic structure-directing agents to control the formation of zeolite (phillipsite) and silicate hydrate (tobermorite) phases without...
Published: 9/11/2025   |   Inventor(s): Gaurav Sant, Ross Arnold, Mathieu Bauchy, Dante Simonetti, Xin Chen, David Jassby, Lawrence Anovitz, Elena Tajuelo Rodriguez
Keywords(s):  
Category(s): Materials, Materials > Metals, Materials > Functional Materials, Energy & Environment
Reagents Targeting Neurodegenerative Diseases and Traumatic Brain Injury
Misfolding and aggregation of proteins, such as beta-amyloid (Aß), alpha-synuclein (a-syn), tau and TAR DNA-binding protein 43 (TDP-43), have been strongly correlated with early onset of neurodegenerative diseases such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Frontotemporal Dementia (FTD), amyotrophic lateral sclerosis (ALS) and...
Published: 2/26/2026   |   Inventor(s): Michael Sierks, Lalitha Venkataraman, Wei Xin
Keywords(s): Alzheimer's Disease, CNS Therapeutics, Dementias, Neurodegenerative Disorders, Neurological Disorders, Phage display
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools
SECURE BIOMETRIC RECOGNITION USING EFFICIENT NEURAL NETWORKS
Value proposition Face Recognition (FR) has become integral to identity management in many practical applications, from unlocking personal devices to facilitating law enforcement and accessing financial services. These systems process sensitive biometric data that, if compromised, can lead to privacy invasions, identity theft, and unauthorized surveillance....
Published: 3/2/2026   |   Inventor(s): Vishnu Boddeti, Wei Ao
Keywords(s):  
Category(s): Computer Software, Informatics, Data Processing/Analysis
Reducing Ischemic Kidney Injury Through Synchronization Modulation Electric Field (SMEF)
Advantages SMEF enables ATP regeneration under ischemic conditions Non-invasive, broad-spectrum applicability to multiple cell and tissue types Enhances organ viability during transplantation Broad Applicability: mechanism is relevant to other ischemic injuries (e.g., heart, brain, liver), opening doors to multi-organ applications Summary Kidney...
Published: 8/8/2025   |   Inventor(s): Wei Chen, Ruisheng Liu
Keywords(s): Organ Transplantation, Renal / Kidney
Category(s): Technology Classifications > Medical > Cell & Tissue Engineering
Just-In-Time Analytics on Large File and Storage Systems
Traditional file systems, such as NTFS and ext3, often struggle to support complex analytics due to limited metadata and the absence of global views. Performing aggregate or top-k queries typically requires exhaustive scanning or pre-built indexes, which are time-consuming and resource-intensive. These limitations hinder efficient data management and...
Published: 1/9/2026   |   Inventor(s): Hao (Howie) Huang, Nan Zhang, Gautam Das, Alexander Szalay, Wei Wang
Keywords(s):  
Category(s): Technology Classifications > Computers Electronics & Software > Computing Architecture, Technology Classifications > Computers Electronics & Software > Databases
Chip-based Nano-optoelectrodes for Optical Voltage Sensing
THE CHALLENGE The challenge in developing reliable, scalable optical voltage sensors lies at the intersection of technical complexity and commercial viability. Current solutions—ranging from fluorescent dyes to random plasmonic nanostructures—face critical limitations: they either require invasive labeling, suffer from photobleaching,...
Published: 10/22/2025   |   Inventor(s): Yuming Zhao, Chuan Xiao, Wei Zhou
Keywords(s):  
Category(s): Technology Classifications > Electronics
Micro-/nano-optoelectrode Arrays by Hierarchical Modular Design
THE CHALLENGE The growing demand for real-time monitoring of complex biological systems—like brain networks, stem-cell growth, and mini-organs—has exposed a major gap in the market: the lack of scalable, integrated sensor platforms that can simultaneously capture both electrical signals and chemical changes in 3D environments. Current...
Published: 10/20/2025   |   Inventor(s): Elieser Mejia, Wei Zhou
Keywords(s):  
Category(s): Technology Classifications > Biotechnology
1 2 3 4 5 6 7 8 9 10 ...