Search Results - tsung-fu+yao

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From Muscle to Mind: Harnessing the Muscle–Brain Axis with Scalable, Muscle-Derived Extracellular Vesicles to Treat Alzheimer’s Disease
Advantages Harnesses the muscle-brain axis, turning human muscle progenitor cells into a renewable source of brain-targeting therapeutic vesicles. Enables scalable, high-yield vesicle production in a compact bioreactor system. Uses a fully xeno-free process for safer, clinically ready, biocompatible manufacturing. Crosses the blood-brain barrier...
Published: 7/15/2026   |   Updated: 7/15/2026   |   Inventor(s): Wanling Xuan, Yao Yao
Keywords(s): Alzheimer's Disease
Category(s): Technology Classifications > Medical > Neuroscience
Novel Laminin Reporter Mouse Line for in vivo Imaging and Laminin Biology Research (Laminin-mCherry/eGFP+/-) Pre-Cre
Advantages First-ever dual-color laminin reporter mouse line. Enables visualization of laminin-γ1 expression in vivo with high fidelity. mCherry signal replicates endogenous laminin distribution without Cre activation. No background eGFP signal ensures clean baseline imaging. Targets the widely expressed γ1 subunit, enhancing...
Published: 7/1/2026   |   Updated: 10/9/2025   |   Inventor(s): Yao Yao
Keywords(s): Animal Models, Neuroscience, Research Tools
Category(s): Technology Classifications > Research Tools/Copyright > Animal Models
Wafer alignment with AFM metrology
Background One of the major challenges in nanoscale manufacturing is defect control. Optical inspection is not an option at the nanoscale level due to the diffraction limit of light, and without inspection high scrap rates can occur. One solution to this problem is inline metrology using atomic force microscopes (AFM). Single chip MEMS based AFMs have...
Published: 1/13/2026   |   Updated: 11/9/2022   |   Inventor(s): Michael Cullinan, Tsung-Fu Yao, Andrew Duenner
Keywords(s):  
Category(s): Physical sciences > Testing equipment, Computer > Semiconductors