Search Results - tnbc

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Use of Acetalax for Treatment of Triple Negative Breast Cancer
Abstract: Triple negative (progesterone receptor (PR)-, estrogen receptor (ER)-, human epidermal growth receptor 2 (HER2)-) breast cancer (TNBC) is an aggressive subtype that affects 15-20% of the 1.7 million cases of breast cancer occurring annually.  Currently, standard treatments of TNBC include cytotoxic chemotherapies, surgery, and radiation. However,...
Published: 4/8/2024   |   Inventor(s): William Reinhold, Matthew Garnett, Vinodh Rajapakse, Yves Pommier, Augustin Luna
Keywords(s): Acetalax, Oxyphenisatin Acetate, Pommier, TNBC, Triple Negative Breast Cancer, Uterine Cancer
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology
METHODS FOR TREATING TRIPLE NEGATIVE BREAST CANCER
METHODS FOR TREATING TRIPLE NEGATIVE BREAST CANCER Researchers at Stanford, funded in part by the Chan Zuckerberg Biohub, have developed a method for treating and predicting treatment efficacy of triple negative breast cancer (TNBC). TNBC is an aggressive subtype of breast cancer that is characterized by a lack of expression of three receptors commonly...
Published: 3/17/2023   |   Inventor(s): Michael Clarke, Robert Hsieh
Keywords(s): Breast Cancer, Cancer, CDK19, Oncology, TNBC, Triple Negative Breast Cancer
Category(s): Technology Classifications > Biology
Targeting LASP1, eIF4A1, eIF4B, and CXC4 with Modulators for treating cancer
Project ID: D2019-32 Background: Breast cancer (BC) is a heterogeneous disease and is the second leading cause of death in women among the cancer mortalities. With the new estimates in 2019, 3 out of 10 women will develop BC in her lifetime and 1 in 7 will succumb to BC. Mortality in BC patients is mainly due to metastasis to the lungs, bone, and brain....
Published: 5/9/2024   |   Inventor(s): Dayanidhi Raman, Cory Howard, John Nemunaitis, F. Charles Brunicardi, Shi-He Liu, Amit Tiwari
Keywords(s): Cancer, CXCL12, CXCL8, CXCLB, CXCR4, eIF4A, LASP1, mTNBC, NACT, pCR, TNBC, Triple negative breast cancer
Category(s): Oncology