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Targeting LASP1, eIF4A1, eIF4B, and CXC4 with Modulators for treating cancer
Project ID: D2019-32 Background: Breast cancer (BC) is a heterogeneous disease and is the second leading cause of death in women among the cancer mortalities. With the new estimates in 2019, 3 out of 10 women will develop BC in her lifetime and 1 in 7 will succumb to BC. Mortality in BC patients is mainly due to metastasis to the lungs, bone, and brain....
Published: 5/9/2024   |   Inventor(s): Dayanidhi Raman, Cory Howard, John Nemunaitis, F. Charles Brunicardi, Shi-He Liu, Amit Tiwari
Keywords(s): Cancer, CXCL12, CXCL8, CXCLB, CXCR4, eIF4A, LASP1, mTNBC, NACT, pCR, TNBC, Triple negative breast cancer
Category(s): Oncology