Search Results - christopher+o%27bryan

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Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 3/4/2025   |   Inventor(s): Yong Zeng, He Yan
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Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
Charge-Neutral Microgels for 3D Cell Culture and Printing
Improves permeability, allowing for easier perfusion than previous compositions These charge-neutral microgels allow for 3D cell culture and printing. Bioprinting, or placement of biological samples into 3D support media, models cellular morphology, heterogeneity, and genetic profiles in a more accurate and reproducible fashion than traditional 2D...
Published: 5/17/2023   |   Inventor(s): Thomas Angelini, Brent Sumerlin, Christopher O'Bryan, Georg Scheutz
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Category(s): Technology Classifications > Engineering > Materials, Technology Classifications > Human Health Care > Diagnostics
Large-Scale 3D Printing of High-Quality Tissue Cells
Automates 3D Tissue Cell Production that Controls Cell Phenotypes, Gene Expression and Stem-Cell Differentiation This automated 3D-cell-culture platform enables industrial-scale manufacturing of high-quality tissue cells. The culture conditions can control cell phenotype, gene expression, and stem-cell differentiation. As tissue engineering and 3D...
Published: 6/27/2021   |   Inventor(s): Thomas Angelini, Cameron Morley, Christopher O'Bryan, Peter McFetridge, Malisa Sarntinoranont, Tanmay Lele, Naohiro Terada
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Category(s): Technology Classifications > Engineering > Mechanical