Search Results - simone+difilippantonio

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Metastatic ovarian cancer mouse models and cell lines for preclinical studies

Abstract: The high mortality rate from ovarian cancers can be attributed to late-stage diagnosis and lack of effective treatment. Despite enormous effort to develop better targeted therapies, platinum-based chemotherapy still remains the standard of care for ovarian cancer patients, and resistance occurs at a high rate. One of the rate limiting factors...

Published: 4/8/2024 | Inventor(s): Simone Difilippantonio, Terry Van Dyke, Ludmila Szabova, Chaoying Yin, Yurong Song

Keywords(s): GDA, GEM Derived Allograft Mouse Model, Genetically Engineered Mouse (GEM) Model, OVARIAN CANCER, SEOC, Serous Epithelial Ovarian Cancer

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials

A Preclinical Model for Mutant Human EGFR-driven Lung Adenocarcinoma

Abstract: Previously described epidermal growth factor receptor- (EGFR) driven tumor mouse models develop diffuse tumors, which are dissimilar to human lung tumor morphology and difficult to measure by CT and MRI scans. Scientists at the National Cancer Institute (NCI) have developed and characterized a genetically engineered mouse (GEM) model of human...

Published: 4/8/2024 | Inventor(s): Simone Difilippantonio, Lionel Feigenbaum, Deborah Householder, Philip Martin, Zoe Ohler, Terry Van Dyke

Keywords(s): EGFR, Epidermal Growth Factor Receptor, GEM, Genetically Engineered Mouse, Lung adenocarcinoma, lung cancer, mouse model, Ohler Weaver, respiratory

Category(s): Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Oncology

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

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Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers

Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources

All-Fiber Multicore Fiber Laser Devices

Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li

Keywords(s):

Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources