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A Preclinical Model for Mutant Human EGFR-driven Lung Adenocarcinoma
Abstract: Previously described epidermal growth factor receptor- (EGFR) driven tumor mouse models develop diffuse tumors, which are dissimilar to human lung tumor morphology and difficult to measure by CT and MRI scans. Scientists at the National Cancer Institute (NCI) have developed and characterized a genetically engineered mouse (GEM) model of human...
Published: 4/8/2024   |   Inventor(s): Simone Difilippantonio, Lionel Feigenbaum, Deborah Householder, Philip Martin, Zoe Ohler, Terry Van Dyke
Keywords(s): EGFR, Epidermal Growth Factor Receptor, GEM, Genetically Engineered Mouse, Lung adenocarcinoma, lung cancer, mouse model, Ohler Weaver, respiratory
Category(s): Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Oncology