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Exploiting Vulnerabilities and Security Threats in Retrieval-Augmented Generative Models: The LIAR Attack Framework
Invention Description Retrieval-Augmented Generative (RAG) models boost generative AI’s accuracy by connecting large language models (LLMs) with the most current, external, knowledge sources. RAG models are widely used in fact-checking, information retrieval, and AI-driven search engines. Despite their utility, adversarial threats can exploit...
Published: 1/30/2026   |   Inventor(s): Zhen Tan, Chengshuai Zhao, Raha Moraffah, Huan Liu
Keywords(s): Artificial Intelligence, Data Mining, Large Language Models, Machine Learning, Natural Language Processing
Category(s): Artificial Intelligence/Machine Learning, Cybersecurity, Computing & Information Technology, Intelligence & Security, Physical Science
Supercharged fluorescent protein biosensors for real-time lanthanide monitoring
Background Rare earth elements—particularly lanthanides like terbium, thulium, and dysprosium—are essential to technologies underpinning renewable energy, electrified transportation, high-performance magnets, and medical imaging. As demand accelerates, sustainable extraction and recycling processes require precise monitoring of these valuable...
Published: 1/30/2026   |   Inventor(s): Andrew Ellington, Kevin Huang, David Walker
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Physical sciences > Environmental & sustainable solutions
Genetically engineered microbes for resilient biomanufacturing in space environments
Background As space missions grow longer and more complex, the need for sustainable biomanufacturing systems becomes increasingly urgent. Biological production of materials, nutrients, and pharmaceuticals offers a self-sufficient approach to supporting human exploration and settlement beyond Earth. However, wild-type microorganisms used in terrestrial...
Published: 1/30/2026   |   Inventor(s): Hal Alper, Mayur Bansal, Sangdo Yook
Keywords(s):  
Category(s): Life sciences > Metabolic engineering
Wearable electronic tattoo for real-time hydration monitoring
Background Accurate hydration assessment is essential for maintaining health, perfor­mance, and safety; even mild dehydration can impair cognition, physical function, and cardiovascular stability. Populations such as older adults, athletes, outdoor laborers, military personnel, and individuals with limited access to clinical care are particularly...
Published: 1/30/2026   |   Inventor(s): Nanshu Lu, Matija Jankovic, Sarnab Bhattacharya, Seungmin Kang, Edward Coyle
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Personalized ASR system for accurate recognition of dysarthric speech
Background Dysarthria is a neurological speech disorder that affects the clarity and intelligibility of spoken language, often resulting from conditions such as stroke, ALS, Parkinson’s disease, or cerebral palsy. Individuals with dysarthria experience slurred or slowed speech, making verbal communication difficult and impacting quality of life. While...
Published: 1/30/2026   |   Inventor(s): Jun Wang, Beiming Cao
Keywords(s):  
Category(s): Life sciences > Medical technology > TechBio (software innovation in healthcare), Life sciences > Medical technology
Wearable ultrasound and EEG patch for noninvasive REM sleep enhancement
Background Sleep is essential for emotional regulation, cognitive function, and overall health. Chronic sleep disruption, prevalent among individuals with PTSD, shift workers, and military personnel, affects tens of millions and contributes to serious long-term health consequences. Despite growing awareness, most existing sleep aid technologies fail...
Published: 1/30/2026   |   Inventor(s): Huiliang Wang, Kai Wing Tang, Jinmo Jeong, Mengmeng Yao
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Microfluidic evaporator concentrator for increasing analyte concentration in small-volume aqueous samples
Background Point-of-care diagnostics, environmental monitoring, and biomanufacturing increasingly require the detection of low concentrations of biomolecules and other non-volatile analytes in aqueous samples, yet many portable analytical systems lack sufficient sensitivity without a preconcentration step. Existing methods such as centrifugal evaporation,...
Published: 1/30/2026   |   Inventor(s): Tanya Hutter, Yufeng Su
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Diagnostic
Bifunctional fusion protein for biofilm degradation and quorum sensing disruption
Background Bacterial biofilms pose a major challenge in clinical and industrial environments due to their dense extracellular matrix and heightened tolerance to antibiotics and immune responses. Infections involving biofilms, particularly those caused by Pseudomonas aeruginosa, are difficult to eradicate and contribute to chronic wounds, persistent...
Published: 1/30/2026   |   Inventor(s): Hugh Smyth, Tom Smisek, Rex Moore, Nila Murali, John Schroeder, Walter Fast
Keywords(s):  
Category(s): Life sciences > Therapeutics > Biologic
Dual-stiffness passive prosthetic ankle for direction-dependent stability
Background Lower-limb amputees often struggle to maintain balance and stability during everyday activities, particularly when turning or navigating uneven surfaces, because the loss of natural ankle musculature and proprioception limits their ability to adapt to changing loads and directions. Most prosthetic ankles provide a single fixed stiffness,...
Published: 1/30/2026   |   Inventor(s): Richard Neptune, Kendrick Neptune
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Real-time optical microdialysis sensor for continuous metabolite monitoring
Background Continuous, real-time monitoring of small molecule metabolites in living tissue is critical for managing conditions like traumatic brain injury (TBI), where rapid shifts in metabolism can precede clinical deterioration. Traditional methods such as microdialysis allow for extracellular fluid sampling of metabolites like glucose, lactate,...
Published: 1/30/2026   |   Inventor(s): Tanya Hutter, Tse-Ang Lee
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
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