Search Results - new+chemical+entity

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Compounds and Methods for Treating Cancer by Destroying Cancer Stem Cells (UCLA Case No. 2021-286)
Researchers from UCLA’s Department of Chemistry and Biochemistry and the Department of Radiation Oncology have synthesized a set of compounds for the eradication of cancer stem cells. These compounds are predicted to cross the blood brain barrier and show promise as effective interventions for glioblastoma in both in vitro and in vivo assays. BACKGROUND:...
Published: 7/11/2024   |   Inventor(s): Michael Jung, Frank Pajonk
Keywords(s): blood-brain barrier, Brain, Cancer, Cancer stem cells, drug screening, GBM, Glioblastoma, Glioma, new chemical entity
Category(s): Therapeutics > Oncology, Therapeutics > CNS and Neurology, Therapeutics > Stem Cells And Regenerative Medicine
Monomeric and Oligomeric Compounds as Contraceptives and Endocrine Therapeutics
Abstract: The options for male contraceptives are limited. Research is ongoing to develop a male contraceptive based on hormonal activity. Testosterone is one of the hormones necessary in producing sperm. Testosterone is absolutely required as a hormone for male fertility. Derivatives of testosterone for male contraceptives currently in clinical trials...
Published: 4/8/2024   |   Inventor(s): Min Lee, Diana Blithe, Pranab Gupta, Bashir Kaskar, Ming-Teh Lin
Keywords(s): Blithe, CONTRACEPTIVE, Estrogenic Activity, Eunice Kennedy Shriver National Institute of Child Health an, Lee, Male Contraceptive, MONOMERIC, NCE, New Chemical Entity, NICHD, OLIGOMERIC
Category(s): Application > Therapeutics, TherapeuticArea > Reproductive Health, TherapeuticArea > Endocrinology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing