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Search Results - liyuan+ma
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Transgenic Mouse Model for Marfan Syndrome Research
Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...
Published: 12/23/2025
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Inventor(s):
Li Li
,
Shichao Wu
,
Jiawei Zhao
Keywords(s):
Category(s):
Technology Category > Research tools
,
Technology Category > Animal models
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Technology Category > Biology
,
Technology Category > Diagnostic
Glanceability in Augmented Reality Systems
THE CHALLENGE Challenge in developing head-worn augmented reality (AR) devices lies in creating systems that can deliver timely, context-aware digital content without disrupting the user’s primary tasks. While there is strong market demand for hands-free, real-time information access—especially in sectors like manufacturing, healthcare,...
Published: 7/9/2025
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Inventor(s):
Doug Bowman
,
Feiyu Lu
,
Wallace Santos Lages
,
Shakiba Davari-Najafabadi
,
Lorance Lisle
,
Yuan Li
Keywords(s):
Category(s):
Technology Classifications > Consumer Products
DNA aptamer technology for Coenzyme A detection and cellular imaging
Researchers developed a DNA aptamer that specifically targets Coenzyme A, enabling easy and accurate detection in cells. This technology is more specific and simpler than current methods, supporting diagnostics, research, and treatments for diseases involving CoA imbalance. Background The field of biochemical research and medical diagnostics increasingly...
Published: 1/13/2026
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Inventor(s):
Yi Lu
,
Whitney Besetzny
,
Yuan Ma
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug screening
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Life sciences > Research tools > Tool/assay/screening platform
ARPLA: a revolutionary glycoRNA imaging tool with precision and power
Background/problem Glycosylated RNAs (GlycoRNAs) are a newly discovered class of molecules involved in glycosylation. They have been found on the surfaces of various cell types, organisms, and species, further advancing the role of RNA in biological processes. Despite this, our knowledge of glycoRNAs and their functions remains limited, primarily...
Published: 1/13/2026
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Inventor(s):
Yi Lu
,
Yuan Ma
,
Weijie Guo
,
Quanbing Mou
Keywords(s):
Category(s):
Life sciences > Research tools > Tool/assay/screening platform
SPACX- A silicon-based Photonic accelerator for DNN Chiplets architecture
The continuous increase in size and complexity of deep neural network (DNN) models leads to rapidly increasing demand for computing capacity which has outpaced the scaling capability of conventional monolithic chips. Chiplet-based DNN accelerators have emerged as a promising solution for continuous scaling. Nevertheless, the metallic-based interconnects...
Published: 1/9/2026
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Inventor(s):
Yuan Li
,
Ahmed Louri
Keywords(s):
Category(s):
Technology Classifications
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Technology Classifications > Computers Electronics & Software
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Technology Classifications > Computers Electronics & Software > Artificial Intelligence
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Technology Classifications > Computers Electronics & Software > Processing Chips
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Technology Classifications > Computers Electronics & Software > Computing Architecture
Real-Time RT-PCR Assay for the Rapid Detection of Rabies and Other Lyssaviruses
Rabies occurs in more than 150 countries and territories, resulting in at least 55,000 human deaths per year worldwide according to World Health Organization estimates. Rabies is a vaccine-preventable viral disease caused by numerous lyssaviruses that are found in a variety of animal species throughout the world. Rabies virus infects the central nervous...
Published: 4/24/2025
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Inventor(s):
Yu Li
Keywords(s):
assay
,
DA4XXX
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DDXXXX
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Diagnostics
,
LYSSAVIRUSES
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Modified
,
NCEZID
,
NCEZID-DHCPP
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Non-rabies
,
Probe
,
rabies
,
REAL-TIME
,
RT-PCR
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VLXXXX
,
VOXXXX
,
WBXXXX
,
WGXXXX
,
WHXXXX
,
WIXXXX
,
XEXXXX
,
YBXXXX
,
YGXXXX
Category(s):
Collaboration Sought > Collaboration
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Collaboration Sought > Licensing
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Application > Occupational Safety and Health
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TherapeuticArea > Infectious Disease
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Application > Consumer Products
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Application > Therapeutics
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Application > Research Materials
,
Application > Diagnostics
Universal Diagnostic Assay for Detection and Identification of Poxviruses in Clinical Samples
CDC researchers have developed an assay for detection and diagnosis of poxviruses within clinical samples or from lab culture-systems. The assay specifically targets chordopoxviruses (except avipoxviruses) for PCR-based identification; an improvement upon the current standard of cell culturing methodologies. Individual chordopoxvirus species can cause...
Published: 4/24/2025
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Inventor(s):
Inger Damon
,
Hui Zhao
,
Yu Li
Keywords(s):
ASSAYS
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CDC Docket Import
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CDC Docket Import CDC Prosecuting
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CHORDOPOXVIRUSES
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DA4BXX
,
DA4XXX
,
DAXXXX
,
diagnostic
,
DXXXXX
,
OID-NCEZID-DHCPP
,
VLXXXX
,
VOXXXX
,
WBXXXX
,
WFXXXX
,
WIXXXX
,
WMXXXX
,
XCXXXX
,
XEXXXX
,
YBXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Occupational Safety and Health
,
Application > Therapeutics
,
TherapeuticArea > Infectious Disease
,
Application > Consumer Products
,
Application > Diagnostics
,
Application > Research Materials
Method for 3D Nonlinear Structured Illumination Super-resolution Imaging
Researchers at the University of Arizona have developed a super-resolution microscopy method that is faster, easier to use, and has less artifacts than current super-resolution methods. The result is a 3D dual-color stimulated emission depletion (STED) nonlinear structured illumination (NL-SIM) microscope. Using a combination of low coherent light and...
Published: 4/3/2023
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Inventor(s):
Leilei Peng
,
Yu Li
,
Han Zhang
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
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Technology Classifications > Imaging & Optics > Medical Imaging
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Technology Classifications > Imaging & Optics > Microscopy, Spectroscopy, Polarimetry
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 1/9/2026
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Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
High throughput toxicity assay on coordinately ordered single cells with individual identity
INV-18104 Background Cytotoxicity plays an important role in understanding biological mechanisms, detecting diseases, and screening therapeutics. Cytotoxicity measurement is usually carried out by incubating cells in different sized wells with a specific treatment, which yields results based on the average response of cells in the same well. However,...
Published: 8/20/2025
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Inventor(s):
Ming Su
,
Qingxuan Li
,
Liyuan Ma
Keywords(s):
Category(s):
Technology Classifications > 1. Life Science > Therapeutics
,
Technology Classifications > 1. Life Science > Drug Discovery
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