Search Results - liuwei+jiang

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Hybrid Lighting Phosphors with High Quantum Efficiency, and Enhanced Thermal and Photostability

This rare-earth element-free invention can be used in LEDs to generate the entire visible spectrum Invention Summary: The use of rare earth elements in the phosphor coating of light-emitting diodes (LEDs) and compact fluorescent lamps (CFLs) raises environmental...

Published: 11/7/2024 | Inventor(s): Jing Li, Yang Fang, Wei Liu

Keywords(s): LEDs, Photonics and photovoltaics

Category(s): Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Polymers/Composites/Materials, Technology Classifications > Electronics/Semiconductor

Improved Methods For Cryopreservation Of Cells, Tissues, And Organs

Summary: The National Eye Institute seeks research co-development partners and/or licensees for novel methods of cryopreserving cells, tissues, and organs via FOXO1 activation and other mechanisms. Description of Technology: The cornea is a critical part of the eye that helps prevent debris from entering and refracts light for proper vision. Corneal...

Published: 9/9/2024 | Inventor(s): Jingxing Ou, Kiyoharu Miyagishima, Guanghui Jin, Wei Li, Lihao Ge

Keywords(s):

Category(s): Application, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Eye / Ear / Nose / Throat

Biomimetic high-strength bone implant polymer material

Problem Bone defects are a global issue affecting millions, caused by factors such as trauma, aging, disease, surgical resections, and congenital abnormalities. There are natural and synthetic options for bone grafts or replacement. A natural bone graft may come from the patient or a donor and is surgically inserted and provides a surface for the remaining...

Published: 4/12/2024 | Inventor(s): Wei Li, Hanyu Zhu, Vincent Wang

Keywords(s):

Category(s): Life sciences > Biomaterials, Life sciences > Therapeutics > Synthetic biology

DNA Methylation Barriers

In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...

Published: 6/5/2024 | Inventor(s): Li Liu, Jingmin Shu

Keywords(s):

Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices

Knitted strain sensor for pharyngeal rehabilitation

Problem Dysphagia, or swallowing dysfunction, affects 9.5 million people in the United States. Dysphagia poses significant risks including malnutrition, dehydration, aspiration pneumonia, and death. Dysphagia is associated with diseases including stroke, muscular dystrophy, and throat cancer. The impact of dysphagia extends beyond physical discomfort,...

Published: 2/15/2024 | Inventor(s): Jonathan Chen, James Sulzer, Corinne Jones, David Zhang, Drake Rowland, Wei Li

Keywords(s):

Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Diagnostic

Vapor-Deposited Perovskite Film for Photovoltaic Applications

Background Perovskites have been widely considered as promising next-generation materials for future display and solid-state lighting applications. Most perovskite LEDS are mainly produced via solution processing, and over 20% external quantum efficiencies (EQE) in LEDs have been achieved in recent studies. However, vacuum-based deposition has attracted...

Published: 12/14/2023 | Inventor(s): Jian Li

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Semiconductors, Materials & Processes, Physical Science, Manufacturing/Construction/Mechanical, Energy & Power, Alternative Energy

Nutraceuticals for Preventing Leaky Gut

Image Legend: Control intestinal organoids and organoids conditioned to have a leak, or more permeable barrier, were treated with nutraceuticals which clearly prevented increased permeability in the “leaky” organoids. Similar findings were observed in cell culture and in vivo Invention Summary: More than 22 million Americans...

Published: 10/21/2024 | Inventor(s): Ronaldo Ferraris, Nan Gao, Wei Li

Keywords(s):

Category(s): Technology Classifications > Food, Nutrition and Nutraceuticals, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

Vapor Deposited and Doped Perovskite Thin Film for LED Applications

Background Perovskites have widely been considered as promising next-generation materials for future display and solid-state lighting applications. Most current perovskite LEDs are produced using solution processing, and over 20% external quantum efficiencies (EQE) in LEDs have been achieved in recent studies. Vacuum-based deposition has also attracted...

Published: 10/1/2024 | Inventor(s): Tianxin Li, Jian Li, Lin Song Li

Keywords(s): Fuel Cells, Energy, Materials and Electronics

Category(s): Physical Science, Manufacturing/Construction/Mechanical, Advanced Materials/Nanotechnology, Energy & Power

Strategies to Protect Mammalian Neural Tissue Against Cold and Potentially Other Metabolic Stresses and Physical Damages

Abstract: Researchers at the National Eye Institute (NEI) have discovered an invention describing a composition and method(s) of using such composition for preserving viability of cells, tissues, or organs at a low temperature (around 4ºC). Current cold storage solutions or methods for cells, tissues, and organs are suboptimal due to irreversible...

Published: 4/8/2024 | Inventor(s): Jingxing Ou, Wei Li, Kiyoharu Miyagishima

Keywords(s): Cold Storage, Cold-sensitive, Hypothermia, lysosome, Mitochondria, National Eye Institute, NEI, neural injury, Ou, Protein Degradation, TRANSPLANTATION

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Cardiology, Application > Research Materials, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat, TherapeuticArea > Nephrology

Establishment of Induced Pluripotent Stem Cells (iPSC) from the Thirteen-lined Ground Squirrel

Abstract: The limited choice in cell types available for in vitro studies has become an obstacle in hibernation research. Researchers at the National Eye Institute for the first time have successfully established iPSC line(s) from a mammalian hibernator, which can be potentially used to generate various cell types and tissue models for in-depth mechanistic...

Published: 4/8/2024 | Inventor(s): Jingxing Ou, Barbara Mallon, Wei Li

Keywords(s): cellular stress, coldness, hibernation, Induced Pluripotent Stem Cell (iPSC), Li, neural injury, Squirrel

Category(s): Application > Research Materials, Collaboration Sought > Licensing, TherapeuticArea > Neurology

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