Search Results - life+sciences+%3e+therapeutics

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Biomimetic HDL Nanoparticles for Treatment of Cancer, Immune and Inflammatory Disorders, and Cardiovascular Disease

SHORT DESCRIPTION Self-assembling biomimetic high-density lipoprotein nanoparticle (HDL NP) platform technology with a soft organic core, designed to more closely replicate key functional properties of mature human HDL for therapeutic use in cardiovascular disease, cancer, and inflammatory/immune disorders. INVENTORS Colby Thaxton* Northwestern...

Published: 6/16/2026 | Updated: 6/16/2026 | Inventor(s):

Keywords(s): Atherosclerosis, Autoimmune disease, Breast cancer, Cancer/Oncology, Cardiology and Cardiovascular disease, Gene therapy, Immunology, Immunotherapy, Inflammation, Nanomaterials, Nanoparticle, Nanotechnology, Nucleic Acids, Platform technology, Prostate cancer, Research tool, Small molecule, Targeted therapy, Therapeutics

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics

Protein Degraders of NSD2 for Targeted Treatment of Head and Neck Cancers

SHORT DESCRIPTION Targeted protein degraders that selectively eliminate NSD2 for improved treatment of head and neck cancers. INVENTORS Gary Schiltz* Weinberg College of Arts and Sciences, Department of Chemistry Yanis Boumber * Principal Investigator NU Tech ID: NU 2023-140 IP STATUS U.S....

Published: 6/16/2026 | Updated: 6/16/2026 | Inventor(s):

Keywords(s): Cancer/Oncology, Head and neck cancer, PROTAC, Small molecule, Targeted protein degradation, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

A Targeted Pharmacotherapy Approach to Aid Opioid Tapering

SHORT DESCRIPTION A pharmacotherapy to improve opioid tapering success by countering opioid-induced adaptations in cortical receptor activity. INVENTORS Apkar Apkarian* Principal Investigator Marwan Baliki * Principal Investigator NU Tech ID: NU 2025-023 IP STATUS US Patent Pending DEVELOPMENT...

Published: 6/16/2026 | Updated: 6/10/2026 | Inventor(s):

Keywords(s):

Category(s): Life Sciences > Therapeutics

Retargetable and Metabolically Tunable CAR Cell Platforms for Durable, Antigen‑Specific Cancer Therapy

SHORT DESCRIPTION A modular immunotherapy platform that combines hapten‑redirectable chimeric antigen receptor (CAR) constructs with itaconate‑programmed, memory‑like immune cells to deliver safer, more durable, and tunable antigen‑specific responses across hematologic and solid tumors. NU TECH ID NU 2023-021, NU 2024-077 INVENTORS Ashima...

Published: 6/10/2026 | Updated: 6/10/2026 | Inventor(s):

Keywords(s): Autoimmune disease, Cancer Treatment, Cancer/Oncology, Cell therapy, Immunology, Immunotherapy, Inflammation, Leukemia, Lymphoma, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

Recombinant Annexin Therapy for Muscle, Cardiac, and Neuronal Cell Membrane Repair

SHORT DESCRIPTION An annexin-based biological therapeutic that enhances the body's natural cell membrane repair process to reduce skeletal muscle, cardiac, and neuronal cell death and preserve tissue function. INVENTORS INVENTORS Elizabeth McNally* Feinberg School of Medicine, Department of Medicine (Cardiology Division) Alexis...

Published: 6/10/2026 | Updated: 6/10/2026 | Inventor(s):

Keywords(s): Biologic, Cardiomyopathy, DMD - Duchenne muscular dystrophy, Inflammation, Membrane injury and repair, Neurodegenerative disease, Rare diseases, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics

Category(s): Life Sciences > Therapeutics

A CSF-Derived Therapy for Psychiatric Disorders

SHORT DESCRIPTION A synthetic soluble ⍺2δ-1-Fc protein to restore brain function in schizophrenia and autism. INVENTORS Peter Penzes* Northwestern University Feinberg School of Medicine, Department of Physiology Marc Dos Santos * Principal Investigator NU Tech ID: NU 2023-196 IP STATUS US...

Published: 6/10/2026 | Updated: 6/10/2026 | Inventor(s):

Keywords(s): ASD - Autism Spectrum Disorder, Biologic, Neurologic disease, Neurology, PSD - Psychotic spectrum disorder, Psychiatric disorder, Schizophrenia, Therapeutics

Category(s): Life Sciences > Therapeutics

Human-Enzyme Mediated, Depletion of Homocysteine for Treating Patients with Homocysteinemia/Homocystinuria

This technology uses engineered human enzymes with enhanced activity to efficiently break down toxic homocysteine, offering improved treatment for metabolic disorders like homocystinuria and hyperhomocysteinemia through enzyme therapy, gene therapy, or pharmaceutical formulations. Background Homocystinuria and hyperhomocysteinemia are inherited or...

Published: 6/4/2026 | Updated: 6/4/2026 | Inventor(s): Everett Stone, George Georgiou

Keywords(s):

Category(s): Life sciences > Therapeutics, Life sciences > Therapeutics > Biologic

Bioactive Supramolecular Peptide Amphiphile Platforms for CNS In Vitro Models, CNS Regeneration, and Neurotherapeutic Delivery

SHORT DESCRIPTION A suite of self‑assembling peptide amphiphile nanostructures and hydrogels that mimic key neurotrophic factors, modulate ionic and electrical microenvironments, and protect therapeutic peptides to enhance neural survival, maturation, and regeneration across CNS diseases and injuries INVENTORS Samuel I Stupp Weinberg...

Published: 6/2/2026 | Updated: 6/2/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, ALS - Amyotrophic Lateral Sclerosis, Biomaterials, CNS - Central Nervous System, Drug delivery, Drug discovery, Drug screening, Hydrogel, In vitro models, Neurology, PD - Parkinson's Disease, Regenerative medicine, Research tool, Scaffold, SCI - Spinal cord injury, Smart/Functional materials, Therapeutics

Category(s): Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics

Micro-Ovary: A Self-Assembled Ovary at Microscale Resolution

fidelity drug screening and reproductive applications. INVENTORS Francesca Duncan* Aubrey Converse Lauren Haky * Principal Investigator NU Tech ID: NU 2025-292 IP STATUS Pending DEVELOPMENT STAGE TRL-4 Prototype Validated in Lab: Self-assembly and follicle encapsulation have been demonstrated...

Published: 6/2/2026 | Updated: 6/2/2026 | Inventor(s):

Keywords(s):

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics

Novel Aminotransferase Inhibitor Platform for the Treatment of Cancer and Neurological Disorders

SHORT DESCRIPTION Novel Aminotransferase Mechanism-Based Inhibitor (MBI) Platform Targeting OAT and GABA-AT as Novel Treatments for Cancer and Neurological Disorders. INVENTORS Richard Silverman* Weinberg College of Arts and Sciences, Department of Chemistry * Principal Investigator DEVELOPMENT...

Published: 6/1/2026 | Updated: 6/1/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, Cancer/Oncology, CNS - Central Nervous System, Colon cancer, Epilepsy, Gastric cancer, Liver cancer, Lung cancer, Neurodegenerative disease, Neurologic disease, Neurology, Pancreatic cancer, PD - Parkinson's Disease, Psychiatric disorder, Small molecule, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

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