Search Results - life+sciences+%3e+therapeutics

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A targeted pharmacotherapy approach to aid opioid tapering
SHORT DESCRIPTION A pharmacotherapy to improve opioid tapering success by countering opioid-induced adaptations in cortical receptor activity. INVENTORS Apkar Apkarian* Principal Investigator Marwan Baliki * Principal Investigator NU Tech ID: NU 2025-023 IP STATUS US Patent Pending DEVELOPMENT...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Therapeutics
Retargetable and Metabolically Tunable CAR Cell Platforms for Durable, Antigen‑Specific Cancer Therapy
SHORT DESCRIPTION A modular immunotherapy platform that combines hapten‑redirectable chimeric antigen receptor (CAR) constructs with itaconate‑programmed, memory‑like immune cells to deliver safer, more durable, and tunable antigen‑specific responses across hematologic and solid tumors. NU TECH ID NU 2023-021, NU 2024-077 INVENTORS Ashima...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s): Autoimmune disease, Cancer Treatment, Cancer/Oncology, Cell therapy, Immunology, Immunotherapy, Inflammation, Leukemia, Lymphoma, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Recombinant Annexin Therapy for Muscle, Cardiac, and Neuronal Cell Membrane Repair
SHORT DESCRIPTION An annexin-based biological therapeutic that enhances the body's natural cell membrane repair process to reduce skeletal muscle, cardiac, and neuronal cell death and preserve tissue function. INVENTORS INVENTORS Elizabeth McNally* Feinberg School of Medicine, Department of Medicine (Cardiology Division) Alexis...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s): Biologic, Cardiomyopathy, DMD - Duchenne muscular dystrophy, Inflammation, Membrane injury and repair, Neurodegenerative disease, Rare diseases, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
A CSF-Derived Therapy for Psychiatric Disorders
SHORT DESCRIPTION A synthetic soluble ⍺2δ-1-Fc protein to restore brain function in schizophrenia and autism. INVENTORS Peter Penzes* Northwestern University Feinberg School of Medicine, Department of Physiology Marc Dos Santos * Principal Investigator NU Tech ID: NU 2023-196 IP STATUS US...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s): ASD - Autism Spectrum Disorder, Biologic, Neurologic disease, Neurology, PSD - Psychotic spectrum disorder, Psychiatric disorder, Schizophrenia, Therapeutics
Category(s): Life Sciences > Therapeutics
Human-Enzyme Mediated, Depletion of Homocysteine for Treating Patients with Homocysteinemia/Homocystinuria
This technology uses engineered human enzymes with enhanced activity to efficiently break down toxic homocysteine, offering improved treatment for metabolic disorders like homocystinuria and hyperhomocysteinemia through enzyme therapy, gene therapy, or pharmaceutical formulations. Background Homocystinuria and hyperhomocysteinemia are inherited or...
Published: 6/4/2026   |   Updated: 6/4/2026   |   Inventor(s): Everett Stone, George Georgiou
Keywords(s):  
Category(s): Life sciences > Therapeutics, Life sciences > Therapeutics > Biologic
Bioactive Supramolecular Peptide Amphiphile Platforms for CNS In Vitro Models, CNS Regeneration, and Neurotherapeutic Delivery
SHORT DESCRIPTION A suite of self‑assembling peptide amphiphile nanostructures and hydrogels that mimic key neurotrophic factors, modulate ionic and electrical microenvironments, and protect therapeutic peptides to enhance neural survival, maturation, and regeneration across CNS diseases and injuries INVENTORS Samuel I Stupp Weinberg...
Published: 6/2/2026   |   Updated: 6/2/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, ALS - Amyotrophic Lateral Sclerosis, Biomaterials, CNS - Central Nervous System, Drug delivery, Drug discovery, Drug screening, Hydrogel, In vitro models, Neurology, PD - Parkinson's Disease, Regenerative medicine, Research tool, Scaffold, SCI - Spinal cord injury, Smart/Functional materials, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics
Micro-Ovary: A Self-Assembled Ovary at Microscale Resolution
fidelity drug screening and reproductive applications. INVENTORS Francesca Duncan* Aubrey Converse Lauren Haky * Principal Investigator NU Tech ID: NU 2025-292 IP STATUS Pending DEVELOPMENT STAGE TRL-4 Prototype Validated in Lab: Self-assembly and follicle encapsulation have been demonstrated...
Published: 6/2/2026   |   Updated: 6/2/2026   |   Inventor(s):  
Keywords(s):  
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics
Novel Aminotransferase Inhibitor Platform for the Treatment of Cancer and Neurological Disorders
SHORT DESCRIPTION Novel Aminotransferase Mechanism-Based Inhibitor (MBI) Platform Targeting OAT and GABA-AT as Novel Treatments for Cancer and Neurological Disorders. INVENTORS Richard Silverman* Weinberg College of Arts and Sciences, Department of Chemistry * Principal Investigator DEVELOPMENT...
Published: 6/1/2026   |   Updated: 6/1/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Cancer/Oncology, CNS - Central Nervous System, Colon cancer, Epilepsy, Gastric cancer, Liver cancer, Lung cancer, Neurodegenerative disease, Neurologic disease, Neurology, Pancreatic cancer, PD - Parkinson's Disease, Psychiatric disorder, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Fatty-Acid Modified Cytotoxins and Peptides for Improved Efficacy, Safety, and Dosing Flexibility
SHORT DESCRIPTION A suite of four complementary technologies for a long-chain fatty‑acid–guided drug delivery platform to achieve superior therapeutic outcomes with reduced toxicity across both oncology and critical care applications. INVENTORS Nathan Gianneschi*, and others Weinberg College of Arts and Sciences,...
Published: 6/2/2026   |   Updated: 6/1/2026   |   Inventor(s):  
Keywords(s): Adjunct therapy, BIO2026, Biologic, Breast cancer, Cancer/Oncology, Chemotherapy, Colon cancer, Lung cancer, Ovarian cancer, Pancreatic cancer, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Small Molecule Inhibitors of Pleckstrin-2 for Treating Myeloproliferative Neoplasms
SHORT DESCRIPTION Small molecule inhibitors of Pleckstrin-2 (Plek2) for treating cell proliferative diseases and disorders, particularly myeloproliferative neoplasms (MPNs). NU Tech IDs: NU 2018-169, NU 2021-005 PRINCIPAL INVESTIGATOR Peng Ji Northwestern University Feinberg School of Medicine, Department of Pathology IP...
Published: 5/27/2026   |   Updated: 5/27/2026   |   Inventor(s):  
Keywords(s): Breast cancer, Cancer/Oncology, Colon cancer, Leukemia, Lung cancer, Pancreatic cancer, Small molecule, Therapeutics
Category(s): Life Sciences > Therapeutics
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