Search Results - georg+mohr

3 Results Sort By:
Thermotargetron for modifying thermophilic microorganisms
The Thermotargetron is a genetic tool for modifying thermophilic micro­organisms using a type-II intron element, TeI3c‑4c. It allows efficient gene inactivation across a broad host range without needing selection markers and can target short gene sequences. Background Renewable fuels like bioethanol are increasingly vital due to rising global...
Published: 8/9/2024   |   Inventor(s): Alan Lambowitz, Georg Mohr, Wei Hong, Qui Cui, Ya-Jun Liu
Keywords(s):  
Category(s): Life sciences > Immunology > Genomics/genetics, Life sciences > Research tools > Tool/assay/screening platform, Physical sciences > Energy > Renewable
Fusion protein technology for site‑specific integration of RNA into DNA genomes
The technology integrates target RNA into DNA genomes by adding short DNA tails to RNA. Direct RNA integration into CRISPR arrays eliminates the use of harsh transfection methods that fragment DNA sequences. Background The development of CRISPR-Cas systems, which are widely used for precise genetic modifications, has advanced the field of genome...
Published: 7/25/2024   |   Inventor(s): Alan Lambowitz, Georg Mohr
Keywords(s):  
Category(s): Life sciences, Life sciences > Therapeutics > Gene editing
Engineered Group II Intron reverse transcriptase for high-resolution RNA analysis
Background The patent portfolio covering group II intron and related reverse transcriptase developed by Dr. Alan Lambowitz at UT Austin, including the highly efficient Thermostable Group II Intron Reverse Transcriptase (TGIRT) enzyme, is available for licensing and commercialization. As many high-profile publications have demonstrated, TGIRT has higher...
Published: 5/29/2024   |   Inventor(s): Alan Lambowitz, Jennifer Stamos, Alfred Lentzsch, Seung Park, Georg Mohr
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform