Search Results - kinase+inhibitor

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Use of Neuronal NOS Inhibitors for Alzheimer's Therapeutic Intervention
PROPOSED TITLE (cut & paste into Alternate Title): Use of Neuronal NOS Inhibitors for Alzheimer's Therapeutic Intervention NU 2023-007 SHORT DESCRIPTION A small molecule based approach that mitigates Alzheimer's neurodegeneration by inhibiting neuronal nitric oxide synthase to prevent tau phosphorylation and reduce Aβ oligomer formation. INVENTORS Richard...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Covalent inhibitor, Kinase Inhibitor, Neurodegenerative disease, Neurology, nNOS, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
CDK19- SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF
CDK19- SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF Researchers at Stanford University have identified new CDK19-selective inhibitors for the treatment of triple negative breast cancer. Breast cancer remains the leading cause of cancer-related mortality among women worldwide. While early cancer detection methods such as genetic biomarker screening...
Published: 3/17/2023   |   Updated: 3/15/2023   |   Inventor(s): Robert Hsieh, Mark Smith, Michael Clarke, Vincent Alford, Andrew Amant
Keywords(s): CDK19, CDK8, Cyclin Dependent Kinases, Kinase Inhibitor, Triple Negative Breast Cancer
Category(s): Technology Classifications > Chemistry