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DNA Nanocaged Enzymes
Compartmentalization increases the overall activity and specificity of encapsulated enzymes by protecting the enzymes, maintaining a high concentration of enzymes and substrates, and promoting substrate channeling. While there have been artificial enzymatic particles that have been created using compartmentalization by virus-like proteins, liposomes,...
Published: 2/13/2025
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Inventor(s): Jinglin Fu, Hao Yan, Neal Woodbury, Zhao Zhao
Keywords(s): Bioanalysis, Catalysis, Enzymes
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
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Controlled Vapor-phase ion-gating (VPIG) and ion capping of Nanomaterials
INV-17050
Background
The investigation of charged particles is a fundamental aspect of several disciplines including physics, astronomy, atmospheric science, and geophysics, and, in addition to ion gauge based pressure metrology, forms a critical component of numerous advanced applications such as mass spectroscopy, plasma acceleration, oncology,...
Published: 9/10/2024
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Inventor(s): Swastik Kar, Ji Hao, Daniel Rubin, Yung Joon Jung
Keywords(s): Carbon nanotubes, nanoparticles
Category(s): Technology Classifications > 2. Physical Science > Electronics/Semiconductors, Not in use > -Materials, Not in use > -Nanotechnology
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Vapour-phase gating induced single-ion detection in graphene and single-wall carbon nanotube networks
INV-17012
Background
Miniaturized devices having ultrasensitive ion detection capability are useful as ion detectors in diverse applications, including detection of radioactive material or other sources of radiation, electron/ion beam calibration, monitoring of pressure or vacuum, and detection of energetic particles from outer space. Carbon nanotubes...
Published: 9/10/2024
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Inventor(s): Swastik Kar, Ji Hao, Yung Joon Jung
Keywords(s):
Category(s): Not in use > -Sensors tech, Not in use > -Materials
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A method for highly selective nucleic acid enrichment for sensitive detection of mutations in cancer and genectic conditions.
This technology increases the fraction of clinically relevant, rare mutant alleles (DNA and/or RNA) to enable high sensitivity detection with common downstream methods such as capped (XNA or PNA) PCR, ddPCR, and sequencing.
Problem:
Liquid biopsy is a simple, minimally invasive, rapidly developing diagnostic method to analyze cell-free nucleic...
Published: 1/8/2025
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Inventor(s): Jinzhao Song, Haim Bau, Michael Mauk, Jorrit Hegge, John van der Oost
Keywords(s):
Category(s): Technology Classifications > Animal Health, Technology Classifications > Diagnostics, Technology Classifications > Medical Devices, Technology Classifications > Research Tools & Reagents
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