Search Results - jian+he

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A Sensitive 3D Lateral Flow Device
This technology is a lateral flow device (LFD), that enables the processing of significantly larger sample volumes while maintaining rapid detection times. By reimagining the structure of the nitrocellulose (NC) membrane—the heart of LFDs—in 3-dimensional structures, this invention incorporates shorter, thinner, and more focused flow sensing...
Published: 4/8/2026   |   Updated: 4/8/2026   |   Inventor(s): Jian Gu, Frederic Zenhausern
Keywords(s):  
Category(s): Technology Classifications > Sensors & Controls > Biologic, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Agriculture & Horticulture, Technology Classifications > Energy, Cleantech & Environmental, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 3/23/2026   |   Updated: 3/23/2026   |   Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
Organ-on-Chip Apparatus for Studying and Monitoring Acoustic Wave Interaction with Gas Bubbles and Disruption of Cellular Barriers
This invention relates to an ultrasound-transparent organ-on-chip platform and a method to study and monitor acoustic wave interaction with gas bubbles and disruption of cellular barriers. The invention can be used for drug screening for ultrasound gas bubble disruption of the blood-brain-barrier (BBB) for brain drug delivery and can be used as a product...
Published: 3/9/2026   |   Updated: 3/9/2026   |   Inventor(s): Jian Gu, Nabhan Fakrudin
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Research Tools > Screening assays
Development of SelU Inhibitors as New Antibiotics
Scientists discovered that special chemical modifications on bacterial tRNA help control protein production and stress responses. They have also developed novel compounds that take advantage of this mechanism to produce antibiotic effects. Background: The field of epitranscriptomics focuses on the chemical modifications of RNA molecules, which are...
Published: 3/5/2026   |   Updated: 3/5/2026   |   Inventor(s): Jia Sheng, Thomas Begley
Keywords(s): antibiotics, inhibitors, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Drug Design and Synthesis
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Updated: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 3/10/2026   |   Updated: 11/7/2025   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 3/20/2026   |   Updated: 10/24/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Direct Carrier Fractional Frequency Synthesizer Using a DiCAD-Based Digital-To-Phase Modulator (Case No. 2025-9AA)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a low-noise, DiCAD-based fractional frequency synthesis system that enables fine frequency resolution and enhanced signal stability for millimeter-wave applications. Background: Millimeter-wave (mmW) communication and radar systems demand carrier frequency...
Published: 10/16/2025   |   Updated: 10/16/2025   |   Inventor(s): Mau-Chung Chang, Christopher Chen, Adrian Tang, Jia Zhou
Keywords(s): 5G, Automotive, Bandwidth (Signal Processing), Communications Satellite, efficiency bandwidth products, electrically-mediated sensing, Extremely High Frequency, Frequency conversion, frequency modulation, high frequency electronics, high-frequency signals, high-speed communications, Imaging, millimeter-wave, Millimeterwave network, Quantum Computer, Radar, satellite imaging, Signal-To-Noise Ratio, Telecommunication
Category(s): Electrical, Electrical > Signal Processing, Software & Algorithms > Communication & Networking, Electrical > Electronics & Semiconductors > Circuits, Software & Algorithms
Systems and Methods for Analyzing Genetic Data for Assessment of Gene Regulatory Activity in Disease Prediciton, Diagnosis and Treatment
Systems and Methods for Analyzing Genetic Data for Assessment of Gene Regulatory Activity in Disease Prediction, Diagnosis and Treatment Princeton Docket # 21-3806 Sequence is at the basis of how the genome and its variations shape chromatin organization, regulate gene expression, and impact traits and diseases. Epigenomic profiling efforts have...
Published: 2/5/2026   |   Updated: 9/29/2025   |   Inventor(s): Olga Troyanskaya, Kathleen Chen, Jian Zhou
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Computer Science and Information Technology
Predicting Genomic Variation Effects on Human Gene Transcription
De novo prediction of tissue-specific expression effect and disease risk for every mutation in a human genome - ExpectoPrinceton Docket # 18-3423Sequence-based models, with their scalability and usage of sequence dependencies, enable a new era of mutation analysis at unprecedented scale that can yield a new perspective on human variation in human diseases...
Published: 9/29/2025   |   Updated: 9/29/2025   |   Inventor(s): Olga Troyanskaya, Jian Zhou, Chandra Theesfeld
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Computer Science and Information Technology
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