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Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 11/7/2025   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
RNA-aptamer-mediated Bacteriophage Purification
A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...
Published: 11/6/2025   |   Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen
Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines
Direct Carrier Fractional Frequency Synthesizer Using a DiCAD-Based Digital-To-Phase Modulator (Case No. 2025-9AA)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a low-noise, DiCAD-based fractional frequency synthesis system that enables fine frequency resolution and enhanced signal stability for millimeter-wave applications. Background: Millimeter-wave (mmW) communication and radar systems demand carrier frequency...
Published: 10/16/2025   |   Inventor(s): Mau-Chung Chang, Christopher Chen, Adrian Tang, Jia Zhou
Keywords(s): 5G, Automotive, Bandwidth (Signal Processing), Communications Satellite, efficiency bandwidth products, electrically-mediated sensing, Extremely High Frequency, Frequency conversion, frequency modulation, high frequency electronics, high-frequency signals, high-speed communications, Imaging, millimeter-wave, Millimeterwave network, Quantum Computer, Radar, satellite imaging, Signal-To-Noise Ratio, Telecommunication
Category(s): Electrical, Electrical > Signal Processing, Software & Algorithms > Communication & Networking, Electrical > Electronics & Semiconductors > Circuits, Software & Algorithms
Systems and Methods for Analyzing Genetic Data for Assessment of Gene Regulatory Activity in Disease Prediciton, Diagnosis and Treatment
Systems and Methods for Analyzing Genetic Data for Assessment of Gene Regulatory Activity in Disease Prediction, Diagnosis and Treatment Princeton Docket # 21-3806 Sequence is at the basis of how the genome and its variations shape chromatin organization, regulate gene expression, and impact traits and diseases. Epigenomic profiling efforts have...
Published: 9/29/2025   |   Inventor(s): Olga Troyanskaya, Kathleen Chen, Jian Zhou
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Medical Devices/Diagnostics, Computer Science and Information Technology
Predicting Genomic Variation Effects on Human Gene Transcription
De novo prediction of tissue-specific expression effect and disease risk for every mutation in a human genome - ExpectoPrinceton Docket # 18-3423Sequence-based models, with their scalability and usage of sequence dependencies, enable a new era of mutation analysis at unprecedented scale that can yield a new perspective on human variation in human diseases...
Published: 9/29/2025   |   Inventor(s): Olga Troyanskaya, Jian Zhou, Chandra Theesfeld
Keywords(s):  
Category(s): Biotechnology/Pharmaceuticals, Computer Science and Information Technology
DeepSEA and Seqweaver: Deep learning frameworks for the identification of de novo disease-causing mutations in noncoding sequences
DeepSEA and Seqweaver: Deep learning frameworks for the identification of de novo disease-causing mutations in noncoding sequences Princeton Docket #s 18-3426, 18-3440 Researchers at Princeton University and Rockefeller University have collaborated to establish methods for the identification of de novo mutations in the vast noncoding genomic sequences....
Published: 9/29/2025   |   Inventor(s): Jian Zhou, Olga Troyanskaya, Christopher Park, Robert Darnell, Chandra Theesfeld
Keywords(s):  
Category(s): Computer Science and Information Technology
Enhancing Luminescent Properties of Vapor-Deposited Perovskite Films Through Vapor Exposure
The industry of perovskite materials has been highly sought out for next generation technology and devices. Perovskite thin films have been used in a large array of applications including light-emitting diodes (LEDs), solar cells, lasers and photodetectors. However, within recent years the widely existing defects (from significant intrinsic point defects...
Published: 10/1/2025   |   Inventor(s): Jian Li
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Physical Science, Semiconductor Devices, Semiconductors, Materials & Processes
Antimicrobial Antibody Signatures of IBD
The incidence of inflammatory bowel disease (IBD), which includes Chron’s disease (CD) and ulcerative colitis (UC), is increasing globally, as is the healthcare burden, with studies showing it as one of the top 5 most expensive GI conditions. Early and accurate diagnosis is strongly associated with better patient outcomes. However, the common...
Published: 8/27/2025   |   Inventor(s): Mahasish Shome, Lusheng Song, Yunro Chung, Jonathan Leighton, Joshua LaBaer, Ji Qiu
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools
Switchable Magnetic Device Holder
The Problem: The prolific use of mobile devices has driven demand for secure, convenient mounting solutions across various environments. Traditional docking stations often rely on adhesive pads and mechanical clamps can be bulky, not universally compatible, and difficult to operate with one hand. Suction based holders are prone to stability issues....
Published: 8/4/2025   |   Inventor(s): Greg Berkeley, Ian Shen
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Lifestyle & Leisure
Boosting Stem Cell Editing with CRISPR Nanoparticles
​ Invention Summary: Gene editing in hematopoietic stem cells (HSCs) holds immense promise for curing genetic blood disorders such as sickle cell anemia and β-thalassemia. However, a major hurdle lies in the safe, efficient, and targeted delivery of CRISPR/Cas9 systems into these delicate stem cells. There is a critical need for innovative...
Published: 8/12/2025   |   Inventor(s): Jinglin Fu, Jian Huang
Keywords(s):  
Category(s): Technology Classifications > Cell Therapy, Technology Classifications > Cancer, Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Nanotechnology, Technology Classifications > Therapeutics
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