Search Results - invasion

2 Results Sort By:
Antisense Oligonucleotides against Cancer Cell Migration and Invasion
Summary: NCI is seeking parties interested in co-developing and/or licensing therapeutic antisense oligonucleotides that target cell migration and cancer metastasis. Description of Technology: Advanced stage cancers are typically marked by metastases of the primary cancer to secondary sites such as lungs, liver, and bones. Such metastatic cancers...
Published: 4/24/2026   |   Updated: 8/2/2023   |   Inventor(s): Stavroula Mili
Keywords(s): Antisense, APC, CANCER, Invasion, Metastasis, MIGRATION, Mili, Net1, OLIGO, oligonucleotide, Oncology, Rab13, RNA
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Application > Therapeutics
Targeting mDia formins to halt tumor microtube formation, invasion, and proliferation in brain tumors
Project ID D2019-34 Tumor therapies must overcome complex obstacles, such as cellular invasion, chemoresistance, and radioresistance. Cells within a brain tumor often form specialized ultralong cellular projections called tumor microtube (TM) projections that allow them to invade new areas of the brain. The networks formed by TMs interconnect with...
Published: 4/15/2026   |   Updated: 1/11/2021   |   Inventor(s): Kathryn Eisenmann, Krista Pettee, Kathryn Becker
Keywords(s): Tumor microtubes, Cancer, Formin, Glioblastoma, High-grade glioma, Invasion, mDia
Category(s): Oncology, Neuroscience