Search Results - ifn-gamma

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Peptide Inhibitors for Viral Infections and as Anti-inflammatory Agents
Abstract: IFN-gamma and IL-10 are cytokine signaling molecules that play fundamental roles in inflammation, cancer growth and autoimmune diseases.  Unfortunately, there are no specific inhibitors of IFN-gamma or IL-10 on the market to date. NCI investigators at the Cancer and Inflammation Program have synthesized short peptides that selectively interfere...
Published: 4/8/2024   |   Inventor(s): Nadya Tarasova, Giorgio Trinchieri, Howard Young, C. Andrew Stewart, Marco Cardone, Alan Perantoni
Keywords(s): IFN-gamma, Interferon gamma, INTERLEUKIN, Peptide, Peptidometic, psoriasis, Synthetic Peptide Inhibitors
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Oncology, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology
Vaccines Comprising Sand Fly Salivary Proteins for Control of Leishmania Infection
This invention relates to the use of several peptides from the salivary glands of various sand fly species for the control of leishmania infection. Many of these peptides were shown to be effective in eliciting potent immune responses in animal models and are excellent candidates for the development of vaccines against the disease. A vaccine comprising...
Published: 10/28/2024   |   Inventor(s): Jesus Valenzuela
Keywords(s): Adn, America, ARIASI, Cellular, Chagase, DA2XXX, DAXXXX, DB2XXX, DBXXXX, DC2XXX, DCXXXX, DDXXXX, Dogs, DXXXXX, Efficient, ELICIT, Fly, Identification, IFN-gamma, Immunity, Infantum, KILLING, Latin, LEISHMANIA, LEISHMANIASIS, Leishmaniasis (Leishmania sp.), Listed LPM Stansberry as of 4/15/2015, LJL143, LJM17, Longipalpis, Lutzomyiz, Method, P., Patent Category - Biotechnology, PERNICIOSUS, POLYPEPTIDES, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, production, proteins, RESULTING, Salivary, SAND, That, Vector, Visceral, WIPO Re:search
Category(s): Collaboration Sought > Collaboration, Application > Research Materials, Application > Diagnostics, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease